Out-Of-Hospital Cardiac Arrest

1
Pipeline Programs
4
Companies
8
Clinical Trials
2 recruiting
0
Approved Products

Pipeline by Development Stage

Preclinical
Phase 1
Phase 1/2
Phase 2
Phase 2/3
Phase 3
On Market
0
0
0
0
1
0
0
Early DiscoveryClinical DevelopmentMarket

Competitive Landscape

4 companies ranked by most advanced pipeline stage

One Biosciences
One BiosciencesFrance - Paris
1 program
1
Rapid infusion of 2 liters of 4oC normal salinePhase 2/31 trial
Active Trials
NCT00391469CompletedEst. Aug 2013
Zoll
ZollCA - San Jose
4 programs
AMSAN/A1 trial
Audiovisual FeedbackN/A1 trial
Automated External DefibrillatorN/A1 trial
Target Temperature Management of 34°CN/A1 trial
Active Trials
NCT03237910TerminatedEst. Jul 2021
NCT01258244CompletedEst. Feb 2015
NCT04446585RecruitingEst. Jan 2027
+1 more trials
PEEL Therapeutics
PEEL TherapeuticsUT - Salt Lake City
2 programs
Double Sequential DefibrillationN/A1 trial
ER-REBOA catheterN/A1 trial
Active Trials
NCT04080986CompletedEst. Aug 2022
NCT06071910RecruitingEst. Dec 2026
Egle Therapeutics
Egle TherapeuticsFrance - Paris
1 program
Dispatcher protocol changeN/A1 trial
Active Trials
NCT04784117CompletedEst. Dec 2022

Trial Timeline

Clinical trial activity over time

2021
2022
2023
2024
2025
2026
2027
One BiosciencesRapid infusion of 2 liters of 4oC normal saline
PEEL TherapeuticsER-REBOA catheter
ZollAutomated External Defibrillator
PEEL TherapeuticsDouble Sequential Defibrillation
ZollAMSA
Egle TherapeuticsDispatcher protocol change
ZollTarget Temperature Management of 34°C
ZollAudiovisual Feedback

Clinical Trials (8)

NCT00391469One BiosciencesRapid infusion of 2 liters of 4oC normal saline

Induction of Mild Hypothermia Following Out-of-hospital Cardiac Arrest

Start: Dec 2007Est. completion: Aug 2013
Phase 2/3Completed
NCT06071910PEEL TherapeuticsER-REBOA catheter

Emergency Resuscitative Endovascular Balloon Occlusion of the Aorta in Out of Hospital Cardiac Arrest

Start: Jun 2024Est. completion: Dec 2026
N/ARecruiting
NCT04446585ZollAutomated External Defibrillator

Cardiac Arrest in Residential Areas With Mobile First-responder Activation

Start: Dec 2021Est. completion: Jan 2027
N/ARecruiting
NCT04080986PEEL TherapeuticsDouble Sequential Defibrillation

DOuble SEquential External Defibrillation for Refractory VF

Start: Sep 2019Est. completion: Aug 2022
N/ACompleted
NCT03237910ZollAMSA

Real Time Amplitude Spectrum Area to Guide Defibrillation

Start: Apr 2019Est. completion: Jul 2021
N/ATerminated
NCT04784117Egle TherapeuticsDispatcher protocol change

Out-of-hospital Cardiac Arrest Epidemiology and Outcomes in Kaunas 2016-2021

Start: Jan 2016Est. completion: Dec 2022
N/ACompleted
NCT02035839ZollTarget Temperature Management of 34°C

Finding the Optimal Cooling tempeRature After Out-of-HoSpiTal Cardiac Arrest

Start: Mar 2014Est. completion: Apr 2016
N/ACompleted
NCT01258244ZollAudiovisual Feedback

Arizona Prehospital CPR Quality Improvement Project

Start: Dec 2010Est. completion: Feb 2015
N/ACompleted

Phase Legend

Preclinical— Lab & animal studies
Phase 1— Safety & dosing
Phase 2— Efficacy testing
Phase 3— Large-scale trials
On Market— Approved & available

Key Insights

2 actively recruiting trials
4 companies competing in this space