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Osteoarthritis Pain

3
Pipeline Programs
4
Companies
3
Clinical Trials
0
Approved Products

Pipeline by Development Stage

Preclinical
Phase 1
Phase 1/2
Phase 2
Phase 2/3
Phase 3
On Market
0
2
0
1
0
0
0
Early DiscoveryClinical DevelopmentMarket

Competitive Landscape

4 companies ranked by most advanced pipeline stage

Acadia Pharmaceuticals
1 program
1
ACP-044Phase 22 trials
Active Trials
NCT05008835Terminated61Est. Nov 2022
NCT04855240Completed239Est. Mar 2022
MSD
MSDIreland - Ballydine
1 program
1
Comparator: Iontophoresis and Laser Doppler with ATPPhase 11 trial
Active Trials
NCT00917696Completed44Est. Jun 2011
Sharp Therapeutics
Sharp TherapeuticsPA - Pittsburgh
1 program
1
Comparator: Iontophoresis and Laser Doppler with ATPPhase 1
Merck & Co.
Merck & Co.RAHWAY, NJ
1 program
Comparator: Iontophoresis and Laser Doppler with ATPPHASE_1

Trial Timeline

Clinical trial activity over time

2021
2022
2023
2024
2025
2026
Acadia PharmaceuticalsACP-044
Acadia PharmaceuticalsACP-044
MSDComparator: Iontophoresis and Laser Doppler with ATP

Clinical Trials (3)

Total enrollment: 344 patients across 3 trials

NCT05008835Acadia PharmaceuticalsACP-044

Evaluate the Efficacy and Safety of ACP-044 in Subjects With Pain Associated With Osteoarthritis of the Knee

Start: Jul 2021Est. completion: Nov 202261 patients
Phase 2Terminated
NCT04855240Acadia PharmaceuticalsACP-044

Evaluate the Efficacy and Safety of ACP-044 for the Treatment of Acute Postoperative Pain Following Bunionectomy

Start: Mar 2021Est. completion: Mar 2022239 patients
Phase 2Completed
NCT00917696MSDComparator: Iontophoresis and Laser Doppler with ATP

Study to Evaluate ATP-induced Pain and ATP-induced Dermal Vasodilation by Iontophoresis (0000-118)(COMPLETED)

Start: Oct 2009Est. completion: Jun 201144 patients
Phase 1Completed

Phase Legend

Preclinical— Lab & animal studies
Phase 1— Safety & dosing
Phase 2— Efficacy testing
Phase 3— Large-scale trials
On Market— Approved & available

Key Insights

4 companies competing in this space

The information on this page is for informational purposes only and should not be used as a substitute for professional medical advice. Drug information is sourced from FDA, DailyMed, and other government databases. Adverse event data from FAERS does not establish causation. Always consult a healthcare professional for medical decisions.