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Oral Hygiene

4
Pipeline Programs
2
Companies
5
Clinical Trials
0
Approved Products

Pipeline by Development Stage

Preclinical
Phase 1
Phase 1/2
Phase 2
Phase 2/3
Phase 3
On Market
0
0
0
3
0
0
1
Early DiscoveryClinical DevelopmentMarket

Competitive Landscape

2 companies ranked by most advanced pipeline stage

ViiV Healthcare
ViiV HealthcareNC - Durham
5 programs
3
1
Sodium bicarbonate/ Sodium FluoridePhase 4
5% KNO3 / 0.2542% NaF dentifrice with 0.5% spherical silicaPhase 2
Sodium bicarbonate and sodium fluoridePhase 2
Sodium bicarbonate plus sodium fluoridePhase 2
Sodium fluorideN/A
GSK
GSKLONDON, United Kingdom
5 programs
Sodium fluorideN/A1 trial
5% KNO3 / 0.2542% NaF dentifrice with 0.5% spherical silicaPHASE_21 trial
Sodium bicarbonate and sodium fluoridePHASE_21 trial
Sodium bicarbonate plus sodium fluoridePHASE_21 trial
Sodium bicarbonate/ Sodium FluoridePHASE_41 trial
Active Trials
NCT02195583Completed62Est. Aug 2014
NCT03267511Completed123Est. Dec 2017
NCT02207400Completed246Est. Apr 2015
+2 more trials

Trial Timeline

Clinical trial activity over time

2021
2022
2023
2024
2025
2026
GSKSodium bicarbonate/ Sodium Fluoride
GSK5% KNO3 / 0.2542% NaF dentifrice with 0.5% spherical silica
GSKSodium bicarbonate and sodium fluoride
GSKSodium bicarbonate plus sodium fluoride
GSKSodium fluoride

Clinical Trials (5)

Total enrollment: 838 patients across 5 trials

NCT01962493GSKSodium bicarbonate/ Sodium Fluoride

An Efficacy Study of Stain Control of a 67% Sodium Bicarbonate Containing Toothpaste on Chlorhexidine Tooth Staining

Start: Sep 2013Est. completion: Nov 2013160 patients
Phase 4Completed
NCT03267511GSK5% KNO3 / 0.2542% NaF dentifrice with 0.5% spherical silica

A Study to Investigate the Stain and Plaque Removal Capability of Two Experimental Potassium Nitrate Dentifrices

Start: Sep 2017Est. completion: Dec 2017123 patients
Phase 2Completed
NCT02207400GSKSodium bicarbonate and sodium fluoride

To Evaluate Efficacy and Tolerability of Sodium Bicarbonate Toothpaste and Its Effect on Opportunistic or Resistant Organisms

Start: Aug 2014Est. completion: Apr 2015246 patients
Phase 2Completed
NCT02207907GSKSodium bicarbonate plus sodium fluoride

To Evaluate the Efficacy and Tolerability of Sodium Bicarbonate Toothpaste

Start: Aug 2014Est. completion: Mar 2015247 patients
Phase 2Completed
NCT02195583GSKSodium fluoride

The Effect of Experimental Dentifrices on Remineralization of Caries Lesions In-situ

Start: Jun 2014Est. completion: Aug 201462 patients
N/ACompleted

Phase Legend

Preclinical— Lab & animal studies
Phase 1— Safety & dosing
Phase 2— Efficacy testing
Phase 3— Large-scale trials
On Market— Approved & available

Key Insights

2 companies competing in this space

The information on this page is for informational purposes only and should not be used as a substitute for professional medical advice. Drug information is sourced from FDA, DailyMed, and other government databases. Adverse event data from FAERS does not establish causation. Always consult a healthcare professional for medical decisions.