Opioid Withdrawal (Disorder)

2
Pipeline Programs
1
Companies
2
Clinical Trials
0
Approved Products

Pipeline by Development Stage

Preclinical
Phase 1
Phase 1/2
Phase 2
Phase 2/3
Phase 3
On Market
0
1
0
1
0
0
0
Early DiscoveryClinical DevelopmentMarket

Competitive Landscape

1 companies ranked by most advanced pipeline stage

US WorldMeds
US WorldMedsKY - Louisville
2 programs
1
1
LofexidinePhase 21 trial
LUCEMYRAPhase 11 trial
Active Trials
NCT06711640Withdrawn0Est. Feb 2026
NCT04070157Terminated4Est. Nov 2019

Trial Timeline

Clinical trial activity over time

2021
2022
2023
2024
2025
2026
US WorldMedsLofexidine
US WorldMedsLUCEMYRA

Clinical Trials (2)

Total enrollment: 4 patients across 2 trials

Randomized, Double-Blind, Placebo-Controlled Pilot Study on the Safety and Effectiveness of LUCEMYRA During an Opioid Taper in Treatment of Withdrawal

Start: Aug 2019Est. completion: Nov 20194 patients
Phase 2Terminated

A Pharmacokinetic, Safety, and Tolerability Study of LUCEMYRA in the Treatment of Opioid Withdrawal Management in Adolescent Subjects

Start: Jun 2025Est. completion: Feb 20260
Phase 1Withdrawn

Phase Legend

PreclinicalLab & animal studies
Phase 1Safety & dosing
Phase 2Efficacy testing
Phase 3Large-scale trials
On MarketApproved & available

Key Insights

1 companies competing in this space