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Ocular Redness

6
Pipeline Programs
3
Companies
4
Clinical Trials
2
Approved Products

Pipeline by Development Stage

Preclinical
Phase 1
Phase 1/2
Phase 2
Phase 2/3
Phase 3
On Market
0
0
0
0
0
4
2
Early DiscoveryClinical DevelopmentMarket

On Market (2)

Approved therapies currently available

Bausch + Lomb
LUMIFY PRESERVATIVE FREEApproved
brimonidine tartrate
Bausch + Lomb
ophthalmic2024
Bausch + Lomb
LUMIFYApproved
brimonidine tartrate
Bausch + Lomb
ophthalmic2017

Competitive Landscape

3 companies ranked by most advanced pipeline stage

Bausch + Lomb
Bausch + LombNJ - Bridgewater
1 program
1
1
LUMIFY(brimonidine tartrate)Phase 3
Bausch Health
Bausch HealthQUEBEC, Quebec, Canada
2 programs
2
BTOS-HAPhase 31 trial
Brimonidine tartrate ophthalmic solution 0.025% preservative-free formulationPhase 31 trial
Active Trials
NCT06803654Completed578Est. Jun 2025
NCT05360784Completed380Est. Nov 2022
Alcon
AlconFORT WORTH, TX
1 program
1
FID 123320Phase 32 trials
Active Trials
NCT06538662Completed283Est. Apr 2025
NCT06444529Completed159Est. Jan 2025

Trial Timeline

Clinical trial activity over time

2022
2023
2024
2025
2026
Bausch HealthBTOS-HA
AlconFID 123320
AlconFID 123320
Bausch HealthBrimonidine tartrate ophthalmic solution 0.025% preservative-free formulation

Clinical Trials (4)

Total enrollment: 1,400 patients across 4 trials

A Study Comparing the Efficacy and Safety of Brimonidine Tartrate Ophthalmic Solution 0.025% With Sodium Hyaluronate Relative to Lumify in Adult Subjects With Ocular Redness

Start: May 2025Est. completion: Jun 2025578 patients
Phase 3Completed

An Investigation of FID 123320 for the Reduction of Ocular Redness in Pediatric and Adult Populations

Start: Oct 2024Est. completion: Apr 2025283 patients
Phase 3Completed

A Double-Masked Comparison of FID 123320 Ophthalmic Solution to Vehicle for the Reduction of Ocular Redness

Start: Aug 2024Est. completion: Jan 2025159 patients
Phase 3Completed
NCT05360784Bausch HealthBrimonidine tartrate ophthalmic solution 0.025% preservative-free formulation

"Efficacy and Safety of Brimonidine Tartrate Preservative-Free Formulation in Adults With Ocular Redness"

Start: May 2022Est. completion: Nov 2022380 patients
Phase 3Completed

Phase Legend

PreclinicalLab & animal studies
Phase 1Safety & dosing
Phase 2Efficacy testing
Phase 3Large-scale trials
On MarketApproved & available

Key Insights

4 late-stage (Phase 3) programs, potential near-term approvals
3 companies competing in this space

The information on this page is for informational purposes only and should not be used as a substitute for professional medical advice. Drug information is sourced from FDA, DailyMed, and other government databases. Adverse event data from FAERS does not establish causation. Always consult a healthcare professional for medical decisions.