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Obstructive Sleep Apnea Syndrome

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Pipeline Programs
4
Companies
5
Clinical Trials
0
Approved Products

Pipeline by Development Stage

Preclinical
Phase 1
Phase 1/2
Phase 2
Phase 2/3
Phase 3
On Market
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Early DiscoveryClinical DevelopmentMarket

Competitive Landscape

4 companies ranked by most advanced pipeline stage

ResMed
ResMedSAN DIEGO, CA
2 programs
Mandibular Retention DeviceN/A1 trial
ORM Narval MRDN/A1 trial
Active Trials
NCT02755662Completed12Est. Jul 2017
NCT01326143Completed360Est. Feb 2019
Inspire Medical Systems
Inspire Medical SystemsMN - Golden Valley
1 program
Activated Inspire® Upper Airway Stimulation SystemN/A1 trial
Active Trials
NCT03844295Completed7Est. Oct 2023
LivaNova
LivaNovaUK - London
1 program
Kinesthetic stimulationN/A1 trial
Active Trials
NCT02789748Completed42Est. Oct 2017
Jazz Pharmaceuticals
Jazz PharmaceuticalsCA - Palo Alto
1 program
XyremPHASE_41 trial
Active Trials
NCT00086281Completed60Est. Nov 2005

Trial Timeline

Clinical trial activity over time

2021
2022
2023
2024
2025
2026
Jazz PharmaceuticalsXyrem
Inspire Medical SystemsActivated Inspire® Upper Airway Stimulation System
LivaNovaKinesthetic stimulation
ResMedMandibular Retention Device
ResMedORM Narval MRD

Clinical Trials (5)

Total enrollment: 481 patients across 5 trials

NCT00086281Jazz PharmaceuticalsXyrem

Trial of Effects of Oral Xyrem and Zolpidem on Sleep-Disordered Breathing in Obstructive Sleep Apnea Patients

Start: Nov 2003Est. completion: Nov 200560 patients
Phase 4Completed
NCT03844295Inspire Medical SystemsActivated Inspire® Upper Airway Stimulation System

Obstructive Sleep Apnea Therapy by Stimulation of the Hypoglossal Nerve

Start: Mar 2019Est. completion: Oct 20237 patients
N/ACompleted
NCT02789748LivaNovaKinesthetic stimulation

PErsonalized and Adaptive Kinesthetic stImulation Therapy, Based on Cardio-respiratory Holter moNitoring, for Sleep Apnea syndrOmes

Start: Jun 2016Est. completion: Oct 201742 patients
N/ACompleted
NCT02755662ResMedMandibular Retention Device

Clinical Impact of 2 Types of Mandibular Retention Devices - Narval O.R.M CadCam Design vs Narval O.R.M Traditional Design - on Obstructive Sleep Apnea (OSA) Therapy: ESTAMPS Study

Start: May 2016Est. completion: Jul 201712 patients
N/ACompleted
NCT01326143ResMedORM Narval MRD

Narval CC Mandibular Repositioning Device in the Second-line Treatment of Severe Obstructive Sleep Apnea Hypopnea (OSAH)

Start: May 2011Est. completion: Feb 2019360 patients
N/ACompleted

Phase Legend

Preclinical— Lab & animal studies
Phase 1— Safety & dosing
Phase 2— Efficacy testing
Phase 3— Large-scale trials
On Market— Approved & available

Key Insights

4 companies competing in this space

The information on this page is for informational purposes only and should not be used as a substitute for professional medical advice. Drug information is sourced from FDA, DailyMed, and other government databases. Adverse event data from FAERS does not establish causation. Always consult a healthcare professional for medical decisions.