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Obstructive Sleep Apnea (OSA)

3
Pipeline Programs
12
Companies
16
Clinical Trials
3 recruiting
0
Approved Products

Pipeline by Development Stage

Preclinical
Phase 1
Phase 1/2
Phase 2
Phase 2/3
Phase 3
On Market
0
2
0
0
0
0
1
Early DiscoveryClinical DevelopmentMarket

Competitive Landscape

12 companies ranked by most advanced pipeline stage

Medtronic
MedtronicNJ - Phillipsburg
1 program
1
Pillar Palatal Implant SystemPhase 41 trial
Active Trials
NCT00730041Terminated51Est. Mar 2009
MSD
MSDIreland - Ballydine
1 program
1
GefapixantPhase 11 trial
Active Trials
NCT03882801Completed24Est. Oct 2019
Sharp Therapeutics
Sharp TherapeuticsPA - Pittsburgh
1 program
1
GefapixantPhase 1
ResMed
ResMedSAN DIEGO, CA
7 programs
CPAP maskN/A1 trial
CPAP maskN/A1 trial
CPAP with min-max recommender toolN/A1 trial
Modified AutoSet AlgorithmN/A1 trial
Positive Airway PressureN/A1 trial
+2 more programs
Active Trials
NCT02805777Withdrawn0Est. Dec 2017
NCT00773721Completed20Est. May 2009
NCT07400861Not Yet Recruiting90Est. Mar 2027
+4 more trials
Human BioSciences
Human BioSciencesWV - Martinsburg
1 program
CPAPN/A1 trial
Active Trials
NCT00706511Completed27Est. Aug 2012
Cryosa
CryosaBRENTWOOD, TN
1 program
Cryosa ProcedureN/A1 trial
Active Trials
NCT07021833Not Yet Recruiting30Est. Feb 2027
Biocorp
BiocorpFrance - Issoire
1 program
Home Respiratory PolygraphyN/A1 trial
Active Trials
NCT03415633Completed251Est. Sep 2018
Inspire Medical Systems
Inspire Medical SystemsMN - Golden Valley
1 program
Inspire® UAS SystemN/A1 trial
Active Trials
NCT07113288Recruiting70Est. Jan 2032
Masimo
MasimoIRVINE, CA
1 program
SedLine EEGN/A1 trial
Active Trials
NCT02639884Completed51Est. Oct 2017
XII Medical
XII MedicalCA - Union City
1 program
XII Medical HGNS SystemN/A1 trial
Active Trials
NCT07049744Recruiting30Est. Jun 2029
UNEEG Medical
UNEEG MedicalDenmark - Allerod
1 program
continuous positive airway pressureN/A1 trial
Active Trials
NCT06711159Recruiting15Est. Dec 2025
T-Therapeutics
T-TherapeuticsUK - Cambridge
1 program
continuous positive airway pressureN/A

Trial Timeline

Clinical trial activity over time

2021
2022
2023
2024
2025
2026
2027
2028
2029
2030
2031
MedtronicPillar Palatal Implant System
MSDGefapixant
ResMedCPAP with min-max recommender tool
CryosaCryosa Procedure
Inspire Medical SystemsInspire® UAS System
XII MedicalXII Medical HGNS System
ResMedfacial scans, videos and heart rate variability measurements
UNEEG Medicalcontinuous positive airway pressure
ResMedPositive Airway Pressure
ResMedPositive Airway Pressure
ResMedCPAP mask
MasimoSedLine EEG
BiocorpHome Respiratory Polygraphy
ResMedCPAP mask
Human BioSciencesCPAP

Showing 15 of 16 trials with date data

Clinical Trials (16)

Total enrollment: 1,114 patients across 16 trials

NCT00730041MedtronicPillar Palatal Implant System

Palatal Implants in Combination With Continuous Positive Airway Pressure to Treat Obstructive Sleep Apnea

Start: Nov 2007Est. completion: Mar 200951 patients
Phase 4Terminated
NCT03882801MSDGefapixant

Safety and Tolerability of Gefapixant (MK-7264) in Participants With Obstructive Sleep Apnea (MK-7264-039)

Start: Apr 2019Est. completion: Oct 201924 patients
Phase 1Completed
NCT07400861ResMedCPAP with min-max recommender tool

Study of Min-Max APAP Recommender Tool

Start: Apr 2026Est. completion: Mar 202790 patients
N/ANot Yet Recruiting
NCT07021833CryosaCryosa Procedure

Clinical Trial of the Cryosa System for the Treatment of Obstructive Sleep Apnea (ARCTIC_AUS)

Start: Aug 2025Est. completion: Feb 202730 patients
N/ANot Yet Recruiting
NCT07113288Inspire Medical SystemsInspire® UAS System

Inspire UAS High Apnea Hypopnea Index (AHI)/High Body Mass Index (BMI) Post-Approval Study

Start: Jul 2025Est. completion: Jan 203270 patients
N/ARecruiting
NCT07049744XII MedicalXII Medical HGNS System

Hypoglossal Nerve Stimulation for the Treatment of Adult Obstructive Sleep Apnea

Start: Jun 2025Est. completion: Jun 202930 patients
N/ARecruiting
NCT06930404ResMedfacial scans, videos and heart rate variability measurements

Data Collection Study to Review Novel Methods for Diagnosing Obstructive Sleep Apnea

Start: Apr 2025Est. completion: Oct 2025300 patients
N/ANot Yet Recruiting
NCT06711159UNEEG Medicalcontinuous positive airway pressure

SLEEPINESS - a Search for a Biomarker of Excessive Daytime Sleepiness in Severe Obstructive Sleep Apnoea - An Explorative Study

Start: Oct 2024Est. completion: Dec 202515 patients
N/ARecruiting
NCT04741854ResMedPositive Airway Pressure

Development of Advanced Leak Detection Technologies for Positive Airway Pressure Devices Therapies

Start: Aug 2020Est. completion: Mar 202127 patients
N/ACompleted
NCT04744038ResMedPositive Airway Pressure

Evaluating the Efficacy of PAP Therapy for Treating OSA in the Home Environment

Start: Aug 2020Est. completion: Mar 2021108 patients
N/ACompleted
NCT02805777ResMedCPAP mask

Vent Flow Study of Prototype Nasal CPAP Mask

Start: May 2017Est. completion: Dec 20170
N/AWithdrawn
NCT02639884MasimoSedLine EEG

Correlation Endoscopic View of Airway Obstruction With RRa in OSA Patients Under DEX Monitored With SedLine EEG

Start: Dec 2015Est. completion: Oct 201751 patients
N/ACompleted
NCT03415633BiocorpHome Respiratory Polygraphy

Validity of a Home Respiratory Polygraphy for the Diagnosis of Obstructive Sleep Apnea

Start: Sep 2015Est. completion: Sep 2018251 patients
N/ACompleted
NCT00773721ResMedCPAP mask

Foam Mask - Assessment of Bioburden in a New Mask Seal Material

Start: Oct 2008Est. completion: May 200920 patients
N/ACompleted
NCT00706511Human BioSciencesCPAP

Metabolic Study of Sleep Apnea in Men and Women

Start: Dec 2007Est. completion: Aug 201227 patients
N/ACompleted
NCT00850434ResMedModified AutoSet Algorithm

Improved Automatic CPAP Algorithm to Treat Obstructive Sleep Apnea (OSA)

Start: Nov 2005Est. completion: Nov 200820 patients
N/ACompleted

Phase Legend

Preclinical— Lab & animal studies
Phase 1— Safety & dosing
Phase 2— Efficacy testing
Phase 3— Large-scale trials
On Market— Approved & available

Key Insights

3 actively recruiting trials targeting 1,114 patients
12 companies competing in this space

The information on this page is for informational purposes only and should not be used as a substitute for professional medical advice. Drug information is sourced from FDA, DailyMed, and other government databases. Adverse event data from FAERS does not establish causation. Always consult a healthcare professional for medical decisions.