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NPC

5
Pipeline Programs
6
Companies
2
Clinical Trials
0
Approved Products

Pipeline by Development Stage

Preclinical
Phase 1
Phase 1/2
Phase 2
Phase 2/3
Phase 3
On Market
0
1
0
4
0
0
0
Early DiscoveryClinical DevelopmentMarket

Drug Modality Breakdown

Monoclonal Antibody
1100%
+ 5 programs with unclassified modality

Competitive Landscape

6 companies ranked by most advanced pipeline stage

Otsuka
OtsukaJapan - Tokushima
1 program
1
OPB-111077Phase 21 trial
Active Trials
NCT03158324Unknown52Est. Nov 2020
MSD
MSDIreland - Ballydine
1 program
1
Pembrolizumab & MRG003Phase 2
Sharp Therapeutics
Sharp TherapeuticsPA - Pittsburgh
1 program
1
Pembrolizumab & MRG003Phase 2
UNION therapeutics
UNION therapeuticsDenmark - Hellerup
1 program
1
Pembrolizumab & MRG003Phase 2
Innovent Biologics
Innovent BiologicsChina - Jiangsu
1 program
1
SintilimabPhase 1Monoclonal Antibody1 trial
Active Trials
NCT04945421Completed30Est. Feb 2023
Lepu Biopharma
Lepu BiopharmaChina - Shanghai
1 program
Pembrolizumab & MRG003PHASE_2

Trial Timeline

Clinical trial activity over time

2021
2022
2023
2024
2025
2026
OtsukaOPB-111077
Innovent BiologicsSintilimab

Clinical Trials (2)

Total enrollment: 82 patients across 2 trials

Phase IIa Dose-Expansion and Biomarker Study of OPB-111077

Start: May 2017Est. completion: Nov 202052 patients
Phase 2Unknown

IBI310 in Combination With Siltilimab in Subjects With Anti-PD-1/PD-L1 Resistance R/M NPC

Start: Jul 2021Est. completion: Feb 202330 patients
Phase 1Completed

Phase Legend

PreclinicalLab & animal studies
Phase 1Safety & dosing
Phase 2Efficacy testing
Phase 3Large-scale trials
On MarketApproved & available

Key Insights

6 companies competing in this space

The information on this page is for informational purposes only and should not be used as a substitute for professional medical advice. Drug information is sourced from FDA, DailyMed, and other government databases. Adverse event data from FAERS does not establish causation. Always consult a healthcare professional for medical decisions.