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Norovirus Infections

0
Pipeline Programs
1
Companies
7
Clinical Trials
0
Approved Products

Pipeline by Development Stage

Preclinical
Phase 1
Phase 1/2
Phase 2
Phase 2/3
Phase 3
On Market
0
0
0
0
0
0
0
Early DiscoveryClinical DevelopmentMarket

Drug Modality Breakdown

Vaccine
1100%
+ 6 programs with unclassified modality

Competitive Landscape

1 companies ranked by most advanced pipeline stage

Vaxart
VaxartSOUTH SAN FRANCISCO, CA
7 programs
VXA-G1.1-NNPHASE_11 trial
VXA-G1.1-NNPHASE_11 trial
VXA-G1.1-NNPHASE_11 trial
VXA-GI.1.NNPHASE_11 trial
VXA-G1.1-NNPHASE_1_21 trial
+2 more programs
Active Trials
NCT07254728Completed76Est. Dec 2024
NCT05213728Completed8Est. Feb 2022
NCT06944717Active Not Recruiting60Est. May 2026
+4 more trials

Trial Timeline

Clinical trial activity over time

2021
2022
2023
2024
2025
2026
VaxartOpen label Bivalent GII.4/GI.1 high dose vaccine 2×10 to the power 11 IU/dose
VaxartVXA-G1.1-NN
VaxartVXA-G1.1-NN
VaxartVXA-G1.1-NN
VaxartVXA-G1.1-NN
VaxartVXA-G1.1-NN
VaxartVXA-GI.1.NN

Clinical Trials (7)

Total enrollment: 540 patients across 7 trials

NCT05626803VaxartOpen label Bivalent GII.4/GI.1 high dose vaccine 2×10 to the power 11 IU/dose

A Study to Determine the Safety and Immunogenicity of Bivalent GI.1 and GII.4 Vaccines in Healthy Volunteers

Start: Jan 2023Est. completion: Oct 2023135 patients
Phase 2Completed

Norovirus Challenge Study

Start: Dec 2021Est. completion: Oct 2023165 patients
Phase 1/2Completed

Immunogenicity & Safety Study of Adenovirus Type 5 (AD5) Based Oral Norovirus Vaccines

Start: Apr 2021Est. completion: Feb 202230 patients
Phase 1/2Completed

A Trial of a Norovirus G1.1 and G2.4 Vaccine Administered Orally to Healthy Participants Aged ≥ 18 Years and ≤ 80 Years Old

Start: Mar 2025Est. completion: May 202660 patients
Phase 1Active Not Recruiting

A Study to Evaluate Vaxart's Oral Bivalent GI.1/GII.4 Norovirus Vaccine in Healthy Lactating Females and Their Nursing Infants

Start: Oct 2023Est. completion: Dec 202476 patients
Phase 1Completed

A Phase 1, Open-label, Safety and Immunogenicity Study of an Oral Multi-dose Administration Regimen With an Adenoviral-vector Based Tablet Norovirus Vaccine (VXA-G1.1-NN) Administered to Healthy Adult Volunteers

Start: Jan 2022Est. completion: Feb 20228 patients
Phase 1Completed

Ph 1b: Safety & Immunogenicity of Ad5 Based Oral Norovirus Vaccine

Start: Apr 2021Est. completion: Jan 202266 patients
Phase 1Completed

Phase Legend

PreclinicalLab & animal studies
Phase 1Safety & dosing
Phase 2Efficacy testing
Phase 3Large-scale trials
On MarketApproved & available

Key Insights

1 companies competing in this space

The information on this page is for informational purposes only and should not be used as a substitute for professional medical advice. Drug information is sourced from FDA, DailyMed, and other government databases. Adverse event data from FAERS does not establish causation. Always consult a healthcare professional for medical decisions.