Skip to main content

Normal Healthy Volunteers

2
Pipeline Programs
3
Companies
4
Clinical Trials
0
Approved Products

Pipeline by Development Stage

Preclinical
Phase 1
Phase 1/2
Phase 2
Phase 2/3
Phase 3
On Market
0
2
0
0
0
0
0
Early DiscoveryClinical DevelopmentMarket

Competitive Landscape

3 companies ranked by most advanced pipeline stage

NImmune Biopharma
NImmune BiopharmaVA - Blacksburg
1 program
1
NIM-1324Phase 11 trial
Active Trials
NCT05019950Completed56Est. Apr 2022
Bausch Health
Bausch HealthQUEBEC, Quebec, Canada
1 program
1
Oral methylnaltrexonePhase 11 trial
Active Trials
NCT01366339Completed37Est. Dec 2003
US WorldMeds
US WorldMedsKY - Louisville
2 programs
LofexidinePHASE_11 trial
Lofexidine hydrochloridePHASE_11 trial
Active Trials
NCT04188730Completed16Est. Mar 2021
NCT01629446Completed6Est. Jun 2012

Trial Timeline

Clinical trial activity over time

2021
2022
2023
2024
2025
2026
NImmune BiopharmaNIM-1324
US WorldMedsLofexidine
US WorldMedsLofexidine hydrochloride
Bausch HealthOral methylnaltrexone

Clinical Trials (4)

Total enrollment: 115 patients across 4 trials

NCT05019950NImmune BiopharmaNIM-1324

Safety Tolerability and Pharmacokinetics of Oral NIM-1324 in Healthy Adult Male and Female Volunteers

Start: Oct 2021Est. completion: Apr 202256 patients
Phase 1Completed
NCT04188730US WorldMedsLofexidine

A Study Evaluating the Relative Bioavailability of Lofexidine Granules for Reconstitution Compared to LUCEMYRA (Lofexidine) Tablets and the Effect of Food on the Bioavailability of the Lofexidine Granules for Reconstitution

Start: Feb 2021Est. completion: Mar 202116 patients
Phase 1Completed
NCT01629446US WorldMedsLofexidine hydrochloride

Lofexidine Mass Balance in Volunteers

Start: May 2012Est. completion: Jun 20126 patients
Phase 1Completed
NCT01366339Bausch HealthOral methylnaltrexone

Tolerance and Pharmacokinetics Study of MNTX Tablets

Start: Oct 2003Est. completion: Dec 200337 patients
Phase 1Completed

Phase Legend

Preclinical— Lab & animal studies
Phase 1— Safety & dosing
Phase 2— Efficacy testing
Phase 3— Large-scale trials
On Market— Approved & available

Key Insights

3 companies competing in this space

The information on this page is for informational purposes only and should not be used as a substitute for professional medical advice. Drug information is sourced from FDA, DailyMed, and other government databases. Adverse event data from FAERS does not establish causation. Always consult a healthcare professional for medical decisions.