Normal Healthy Volunteers
3
Pipeline Programs
2
Companies
3
Clinical Trials
0
Approved Products
Pipeline by Development Stage
Preclinical
Phase 1
Phase 1/2
Phase 2
Phase 2/3
Phase 3
On Market
0
3
0
0
0
0
0
Early DiscoveryClinical DevelopmentMarket
Competitive Landscape
2 companies ranked by most advanced pipeline stage
US WorldMedsKY - Louisville
2 programs2
LofexidinePhase 11 trial
Lofexidine hydrochloridePhase 11 trial
Active Trials
Trial Timeline
Clinical trial activity over time
2021
2022
2023
2024
2025
2026
US WorldMedsLofexidine
US WorldMedsLofexidine hydrochloride
Bausch HealthOral methylnaltrexone
Clinical Trials (3)
Total enrollment: 22 patients across 3 trials
A Study Evaluating the Relative Bioavailability of Lofexidine Granules for Reconstitution Compared to LUCEMYRA (Lofexidine) Tablets and the Effect of Food on the Bioavailability of the Lofexidine Granules for Reconstitution
Start: Feb 2021Est. completion: Mar 202116 patients
Phase 1Completed
Lofexidine Mass Balance in Volunteers
Start: May 2012Est. completion: Jun 20126 patients
Phase 1Completed
Tolerance and Pharmacokinetics Study of MNTX Tablets
Start: Oct 2003Est. completion: Dec 2003
Phase 1Completed
Phase Legend
Preclinical— Lab & animal studies
Phase 1— Safety & dosing
Phase 2— Efficacy testing
Phase 3— Large-scale trials
On Market— Approved & available
Key Insights
2 companies competing in this space