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Non-Hematologic Malignancy

0
Pipeline Programs
2
Companies
3
Clinical Trials
0
Approved Products

Pipeline by Development Stage

Preclinical
Phase 1
Phase 1/2
Phase 2
Phase 2/3
Phase 3
On Market
0
0
0
0
0
0
0
Early DiscoveryClinical DevelopmentMarket

Drug Modality Breakdown

Small Molecule
1100%
+ 1 programs with unclassified modality

Competitive Landscape

2 companies ranked by most advanced pipeline stage

Guardant Health
Guardant HealthPALO ALTO, CA
1 program
Guardant360® Test-Related Clinical Outcomes in Patients Who Share Medical RecordsN/A1 trial
Active Trials
NCT03625557Completed30Est. Apr 2020
Takeda
TakedaTOKYO, Japan
1 program
SapanisertibPHASE_1Small Molecule2 trials
Active Trials
NCT02725268Completed241Est. Oct 2020
NCT02412722Completed61Est. May 2018

Trial Timeline

Clinical trial activity over time

2021
2022
2023
2024
2025
2026
TakedaSapanisertib
TakedaSapanisertib
Guardant HealthGuardant360® Test-Related Clinical Outcomes in Patients Who Share Medical Records

Clinical Trials (3)

Total enrollment: 332 patients across 3 trials

NCT02725268TakedaSapanisertib

A Study of Sapanisertib, Combination of Sapanisertib With MLN1117, Paclitaxel and Combination of Sapanisertib With Paclitaxel in Women With Endometrial Cancer

Start: Apr 2016Est. completion: Oct 2020241 patients
Phase 2Completed
NCT02412722TakedaSapanisertib

A Safety, Tolerability, and Pharmacokinetics Study of MLN0128 as a Single Agent and in Combination With Paclitaxel in Adults With Advanced Nonhematologic Malignancies

Start: Mar 2015Est. completion: May 201861 patients
Phase 1Completed
NCT03625557Guardant HealthGuardant360® Test-Related Clinical Outcomes in Patients Who Share Medical Records

Guardant360® Test-Related Clinical Outcomes in Patients Who Share Medical Records

Start: Apr 2019Est. completion: Apr 202030 patients
N/ACompleted

Phase Legend

PreclinicalLab & animal studies
Phase 1Safety & dosing
Phase 2Efficacy testing
Phase 3Large-scale trials
On MarketApproved & available

Key Insights

2 companies competing in this space

The information on this page is for informational purposes only and should not be used as a substitute for professional medical advice. Drug information is sourced from FDA, DailyMed, and other government databases. Adverse event data from FAERS does not establish causation. Always consult a healthcare professional for medical decisions.