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Neurofibromatosis Type 2

1
Pipeline Programs
3
Companies
3
Clinical Trials
0
Approved Products

Pipeline by Development Stage

Preclinical
Phase 1
Phase 1/2
Phase 2
Phase 2/3
Phase 3
On Market
0
0
0
1
0
0
0
Early DiscoveryClinical DevelopmentMarket

Competitive Landscape

3 companies ranked by most advanced pipeline stage

Sandoz
SandozAustria - Kundl
1 program
1
RAD001, everolimusPhase 21 trial
Active Trials
NCT01345136Terminated4Est. Feb 2024
Heidelberg Pharma
Heidelberg PharmaGermany - Ladenburg
1 program
Whole exome sequencingN/A1 trial
Active Trials
NCT03210285Completed70Est. Jul 2018
Recursion Pharmaceuticals
Recursion PharmaceuticalsSALT LAKE CITY, UT
1 program
REC-2282PHASE_2_31 trial
Active Trials
NCT05130866Terminated25Est. Aug 2025

Trial Timeline

Clinical trial activity over time

2021
2022
2023
2024
2025
2026
Recursion PharmaceuticalsREC-2282
SandozRAD001, everolimus
Heidelberg PharmaWhole exome sequencing

Clinical Trials (3)

Total enrollment: 99 patients across 3 trials

Efficacy and Safety of REC-2282 in Patients With Progressive Neurofibromatosis Type 2 (NF2) Mutated Meningiomas

Start: Jun 2022Est. completion: Aug 202525 patients
Phase 2/3Terminated
NCT01345136SandozRAD001, everolimus

Study of RAD001 for Treatment of NF2-related Vestibular Schwannoma

Start: Jul 2015Est. completion: Feb 20244 patients
Phase 2Terminated
NCT03210285Heidelberg PharmaWhole exome sequencing

WES of NF2-associated in Comparison to Sporadic Vestibular Schwannomas - Correlation With Clinical Data

Start: Jul 2017Est. completion: Jul 201870 patients
N/ACompleted

Phase Legend

PreclinicalLab & animal studies
Phase 1Safety & dosing
Phase 2Efficacy testing
Phase 3Large-scale trials
On MarketApproved & available

Key Insights

3 companies competing in this space

The information on this page is for informational purposes only and should not be used as a substitute for professional medical advice. Drug information is sourced from FDA, DailyMed, and other government databases. Adverse event data from FAERS does not establish causation. Always consult a healthcare professional for medical decisions.