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Neurofibromatosis

2
Pipeline Programs
3
Companies
3
Clinical Trials
1 recruiting
0
Approved Products

Pipeline by Development Stage

Preclinical
Phase 1
Phase 1/2
Phase 2
Phase 2/3
Phase 3
On Market
0
1
0
1
0
0
0
Early DiscoveryClinical DevelopmentMarket

Drug Modality Breakdown

Small Molecule
1100%
+ 2 programs with unclassified modality

Competitive Landscape

3 companies ranked by most advanced pipeline stage

Pfizer
PfizerNEW YORK, NY
1 program
1
Sutent®/SunitinibPhase 2Small Molecule1 trial
Active Trials
NCT01402817Terminated19Est. Feb 2018
Sandoz
SandozAustria - Kundl
1 program
1
TasignaPhase 11 trial
Active Trials
NCT01275586Completed6Est. Oct 2016
AstraZeneca
AstraZenecaCAMBRIDGE, United Kingdom
1 program
Clinical and Demographic Characteristics of Adult p Atients With NEurofibromatosis in RUSsiaN/A1 trial
Active Trials
NCT07088991Recruiting200Est. Mar 2028

Trial Timeline

Clinical trial activity over time

2021
2022
2023
2024
2025
2026
2027
2028
PfizerSutent®/Sunitinib
SandozTasigna
AstraZenecaClinical and Demographic Characteristics of Adult p Atients With NEurofibromatosis in RUSsia

Clinical Trials (3)

Total enrollment: 225 patients across 3 trials

NCT01402817PfizerSutent®/Sunitinib

Study of Sutent®/Sunitinib (SU11248) in Subjects With NF-1 Plexiform Neurofibromas

Start: Mar 2012Est. completion: Feb 201819 patients
Phase 2Terminated

Study of Tasigna®/Nilotinib (AMN107) in Neurofibromatosis (NF1) Patients With Plexiform Neurofibromas

Start: Jan 2011Est. completion: Oct 20166 patients
Phase 1Completed
NCT07088991AstraZenecaClinical and Demographic Characteristics of Adult p Atients With NEurofibromatosis in RUSsia

Clinical and Demographic Characteristics of Adult p Atients With NEurofibromatosis in RUSsia

Start: Jun 2025Est. completion: Mar 2028200 patients
N/ARecruiting

Related Jobs

Phase Legend

PreclinicalLab & animal studies
Phase 1Safety & dosing
Phase 2Efficacy testing
Phase 3Large-scale trials
On MarketApproved & available

Key Insights

1 actively recruiting trials targeting 225 patients
3 companies competing in this space

The information on this page is for informational purposes only and should not be used as a substitute for professional medical advice. Drug information is sourced from FDA, DailyMed, and other government databases. Adverse event data from FAERS does not establish causation. Always consult a healthcare professional for medical decisions.