Nearsightedness

1
Pipeline Programs
2
Companies
2
Clinical Trials
0
Approved Products

Pipeline by Development Stage

Preclinical
Phase 1
Phase 1/2
Phase 2
Phase 2/3
Phase 3
On Market
0
0
0
0
0
1
0
Early DiscoveryClinical DevelopmentMarket

Competitive Landscape

2 companies ranked by most advanced pipeline stage

Sydnexis
SydnexisCA - Del Mar
1 program
1
SYD-101 0.01%Phase 31 trial
Active Trials
NCT03918915CompletedEst. May 2025
Bausch + Lomb
Bausch + LombNJ - Bridgewater
1 program
Experimental: Myopic defocus soft lens designN/A1 trial
Active Trials
NCT06527274Active Not Recruiting25Est. Mar 2025

Trial Timeline

Clinical trial activity over time

2021
2022
2023
2024
2025
2026
SydnexisSYD-101 0.01%
Bausch + LombExperimental: Myopic defocus soft lens design

Clinical Trials (2)

Total enrollment: 25 patients across 2 trials

NCT03918915SydnexisSYD-101 0.01%

The Safety and Efficacy of SYD-101 in Children With Myopia

Start: Apr 2019Est. completion: May 2025
Phase 3Completed
NCT06527274Bausch + LombExperimental: Myopic defocus soft lens design

Effect of Defocus in Soft Contact Lenses on Internal Retinal Vascularization

Start: Jun 2024Est. completion: Mar 202525 patients
N/AActive Not Recruiting

Phase Legend

PreclinicalLab & animal studies
Phase 1Safety & dosing
Phase 2Efficacy testing
Phase 3Large-scale trials
On MarketApproved & available

Key Insights

1 late-stage (Phase 3) programs — potential near-term approvals
2 companies competing in this space