Myotonic Dystrophy 1

2
Pipeline Programs
4
Companies
3
Clinical Trials
1 recruiting
0
Approved Products

Pipeline by Development Stage

Preclinical
Phase 1
Phase 1/2
Phase 2
Phase 2/3
Phase 3
On Market
0
0
1
1
0
0
0
Early DiscoveryClinical DevelopmentMarket

Competitive Landscape

3 companies ranked by most advanced pipeline stage

Harmony Biosciences
Harmony BiosciencesPLYMOUTH MEETING, PA
1 program
1
Pitolisant Oral TabletPhase 21 trial
Active Trials
NCT04886518Completed30Est. Oct 2024
Arrowhead Pharmaceuticals
1 program
1
ARO-DM1 IntravenousPhase 1/21 trial
Active Trials
NCT06138743Recruiting78Est. Dec 2026
Life & Brain
Life & BrainGermany - Bonn
1 program
medical historyN/A1 trial
Active Trials
NCT02729597CompletedEst. Aug 2015

Trial Timeline

Clinical trial activity over time

2021
2022
2023
2024
2025
2026
Harmony BiosciencesPitolisant Oral Tablet
Arrowhead PharmaceuticalsARO-DM1 Intravenous
Life & Brainmedical history

Clinical Trials (3)

Total enrollment: 108 patients across 3 trials

NCT04886518Harmony BiosciencesPitolisant Oral Tablet

Safety and Efficacy of Pitolisant on Excessive Daytime Sleepiness and Other Non-Muscular Symptoms in Patients With Myotonic Dystrophy Type 1

Start: Jun 2021Est. completion: Oct 202430 patients
Phase 2Completed

Study of ARO-DM1 in Subjects With Type 1 Myotonic Dystrophy

Start: Mar 2024Est. completion: Dec 202678 patients
Phase 1/2Recruiting

Tracking the Brain in Myotonic Dystrophies: a 5-year Longitudinal Follow-up Study

Start: May 2007Est. completion: Aug 2015
N/ACompleted

Phase Legend

PreclinicalLab & animal studies
Phase 1Safety & dosing
Phase 2Efficacy testing
Phase 3Large-scale trials
On MarketApproved & available

Key Insights

1 actively recruiting trials targeting 108 patients
4 companies competing in this space