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Mycobacterium Avium-intracellulare Infection

1
Pipeline Programs
3
Companies
19
Clinical Trials
0
Approved Products

Pipeline by Development Stage

Preclinical
Phase 1
Phase 1/2
Phase 2
Phase 2/3
Phase 3
On Market
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1
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Early DiscoveryClinical DevelopmentMarket

Competitive Landscape

3 companies ranked by most advanced pipeline stage

Abbott
AbbottABBOTT PARK, IL
1 program
1
clarithromycinPhase 25 trials
Active Trials
NCT00000644Completed100
NCT00000971Completed24
NCT01354938Completed220Est. Jan 2012
+2 more trials
Amgen
AmgenTHOUSAND OAKS, CA
1 program
trifluridineN/A3 trials
Active Trials
NCT00002037Completed15
NCT06680622Active Not Recruiting126Est. Mar 2028
NCT05198934Completed160Est. Apr 2026
Allergy Therapeutics
Allergy TherapeuticsUK - West Sussex
1 program
ClarithromycinPHASE_2

Trial Timeline

Clinical trial activity over time

2021
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Abbottclarithromycin
Abbottclarithromycin
Amgentrifluridine
Abbottclarithromycin
Abbottclarithromycin
Abbottclarithromycin
Amgentrifluridine
Abbottclarithromycin
Abbottclarithromycin
Abbottclarithromycin
Abbottclarithromycin
Abbottclarithromycin
Abbottclarithromycin
Abbottclarithromycin
Abbottclarithromycin

Showing 15 of 16 trials with date data

Clinical Trials (19)

Total enrollment: 10,725 patients across 19 trials

NCT00598897Abbottclarithromycin

Use of Clarithromycin and Rifabutin for the Treatment of M. Avium Complex (MAC) Lung Disease

Start: Aug 1995Est. completion: May 201789 patients
Phase 4Completed
NCT00600769Abbottclarithromycin

Clarithromycin for the Treatment of Infections Caused by Nontuberculous Mycobacteria (NTM)

Start: Jan 1991Est. completion: May 2017210 patients
Phase 4Completed
NCT05198934Amgentrifluridine

Sotorasib and Panitumumab Versus Investigator's Choice for Participants With Kirsten Rat Sarcoma (KRAS) p.G12C Mutation

Start: Apr 2022Est. completion: Apr 2026160 patients
Phase 3Completed
NCT00644553Abbottclarithromycin

Comparative Study of the Safety and Efficacy of Clarithromycin Extended-Release Tablets Versus Amoxicillin-Clavulanate for the Treatment of Acute Bacterial Sinusitis

Start: May 2003437 patients
Phase 3Completed
NCT00645086Abbottclarithromycin

Comparative Study of 5 Days of M02-472 Clarithromycin Extended-Release Tablets to 7 Days of Clarithromycin Immediate-Release Tablets for the Treatment of Exacerbation of Chronic Bronchitis

Start: Dec 2002465 patients
Phase 3Completed
NCT00121550Abbottclarithromycin

The CLARICOR Trial: Effect of Clarithromycin on Mortality and Morbidity in Patients With Ischemic Heart Disease

Start: Oct 1999Est. completion: Sep 20024,372 patients
Phase 3Completed
NCT00000644Abbottclarithromycin

A Phase II Safety and Efficacy Study of Clarithromycin in the Treatment of Disseminated M. Avium Complex (MAC) Infections in Patients With AIDS

100 patients
Phase 2Completed
NCT06680622Amgentrifluridine

Bemarituzumab in FGFR2b+ Patients With Advanced or Metastatic Adenocarcinoma of the Stomach or Gastroesophageal Junction, Who Failed at Least One Prior Line of Palliative Chemotherapy

Start: Mar 2025Est. completion: Mar 2028126 patients
Phase 2Active Not Recruiting
NCT00205634Abbottclarithromycin

Macrolide Antibiotic Therapy for Patients With Cystic Fibrosis

Start: Dec 2000Est. completion: Oct 200450 patients
Phase 2Completed
NCT00000971Abbottclarithromycin

The Safety and Effectiveness of Clarithromycin Plus Zidovudine or Dideoxyinosine in the Treatment of Mycobacterium Avium Complex (MAC) Infections in Children With AIDS

24 patients
Phase 1Completed
NCT00002037Amgentrifluridine

Evaluation of the Therapeutic Benefit of r-metHuIFN- Gamma in AIDS Patients With Disseminated Mycobacterium Avium-Intracellulare (MAI) Infection: A Multi-Centered Pilot Study

15 patients
N/ACompleted
NCT01354938Abbottclarithromycin

Outcome Study to Evaluate Klaricid XL® (Clarithromycin Modified Release) in Patients With Acute Exacerbation of Chronic Bronchitis

Start: May 2011Est. completion: Jan 2012220 patients
N/ACompleted
NCT01075204Abbottclarithromycin

Clarithromycin Modified Release Observational Study for Evaluation of Treatment, Tolerability & Recovery Time in Saudi & Egyptian Clinical Settings (CLOSER)

Start: Jan 2011Est. completion: Jan 2012335 patients
N/ACompleted
NCT01095978Abbottclarithromycin

Evaluation of the Treatment With Klacid SR in Patients With Acute Tracheitis, Tracheobronchitis and Bronchitis, Acute Exacerbation of Chronic Bronchitis and Mild Community-acquired Pneumonia in Common Clinical Practice in Ukraine

Start: Aug 2009Est. completion: May 20102,822 patients
N/ACompleted
NCT01076166Abbottclarithromycin

Recovery Time in Children With Lower Respiratory Tract Infections Treated With Klacid® Granules for Oral Suspension.

Start: Apr 2009Est. completion: Jan 2010337 patients
N/ACompleted
NCT01076153Abbottclarithromycin

Recovery Time in Thai Patients With Upper or Lower Respiratory Tract Infections Treated With Klacid MR

Start: Dec 2008Est. completion: Apr 2010760 patients
N/ACompleted
NCT00354952Abbottclarithromycin

Selection of Antibiotic Resistance by Azithromycin and Clarithromycin in the Oral Flora

Start: Jul 2002Est. completion: Oct 2003203 patients
N/ACompleted
NCT00002331Abbottclarithromycin

The Safety and Effectiveness of Clarithromycin Plus Ethambutol Used With or Without Clofazimine in the Treatment of MAC in Patients With AIDS

Start: Jan 1994Est. completion: Mar 1995
N/ACompleted
NCT00002336Abbottclarithromycin

The Safety and Effectiveness of Clarithromycin in the Prevention of Mycobacterium Avium Complex (MAC) Infection in HIV-Infected Patients

Start: Nov 1992Est. completion: Nov 1994
N/ACompleted

Phase Legend

PreclinicalLab & animal studies
Phase 1Safety & dosing
Phase 2Efficacy testing
Phase 3Large-scale trials
On MarketApproved & available

Key Insights

3 companies competing in this space

The information on this page is for informational purposes only and should not be used as a substitute for professional medical advice. Drug information is sourced from FDA, DailyMed, and other government databases. Adverse event data from FAERS does not establish causation. Always consult a healthcare professional for medical decisions.