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Muscle Weakness

2
Pipeline Programs
4
Companies
4
Clinical Trials
1 recruiting
0
Approved Products

Pipeline by Development Stage

Preclinical
Phase 1
Phase 1/2
Phase 2
Phase 2/3
Phase 3
On Market
0
0
0
1
0
0
1
Early DiscoveryClinical DevelopmentMarket

Competitive Landscape

4 companies ranked by most advanced pipeline stage

Spine BioPharma
Spine BioPharmaNY - New York
1 program
1
Depo-MedrolPhase 41 trial
Active Trials
NCT05929755Recruiting80Est. May 2027
Prevail Therapeutics
1 program
1
LY2495655Phase 21 trial
Active Trials
NCT01604408Completed201Est. Dec 2013
Defence Therapeutics
Defence TherapeuticsBC - Vancouver
1 program
Low load resistance training with blood flow restrictionN/A1 trial
Active Trials
NCT06334224Unknown18Est. Sep 2024
Stimit AG
Stimit AGSwitzerland - Biel
1 program
Non-invasive electromagnetic stimulationN/A1 trial
Active Trials
NCT05238753Terminated10Est. May 2022

Trial Timeline

Clinical trial activity over time

2021
2022
2023
2024
2025
2026
2027
Spine BioPharmaDepo-Medrol
Prevail TherapeuticsLY2495655
Defence TherapeuticsLow load resistance training with blood flow restriction
Stimit AGNon-invasive electromagnetic stimulation

Clinical Trials (4)

Total enrollment: 309 patients across 4 trials

NCT05929755Spine BioPharmaDepo-Medrol

Depo-Medrol on Psoas After LLIF

Start: May 2023Est. completion: May 202780 patients
Phase 4Recruiting
NCT01604408Prevail TherapeuticsLY2495655

A Study in Older Participants Who Have Fallen and Have Muscle Weakness

Start: May 2012Est. completion: Dec 2013201 patients
Phase 2Completed
NCT06334224Defence TherapeuticsLow load resistance training with blood flow restriction

Acute Physiological Responses to Twice Daily Blood Flow Restriction Training

Start: Nov 2023Est. completion: Sep 202418 patients
N/AUnknown
NCT05238753Stimit AGNon-invasive electromagnetic stimulation

Electromagnetic Stimulation of the Phrenic Nerve in Critically Ill Mechanically Ventilated Patients (STIMIT-II)

Start: Jan 2022Est. completion: May 202210 patients
N/ATerminated

Phase Legend

Preclinical— Lab & animal studies
Phase 1— Safety & dosing
Phase 2— Efficacy testing
Phase 3— Large-scale trials
On Market— Approved & available

Key Insights

1 actively recruiting trials targeting 309 patients
4 companies competing in this space

The information on this page is for informational purposes only and should not be used as a substitute for professional medical advice. Drug information is sourced from FDA, DailyMed, and other government databases. Adverse event data from FAERS does not establish causation. Always consult a healthcare professional for medical decisions.