Mucopolysaccharidosis IV A

1
Pipeline Programs
1
Companies
3
Clinical Trials
0
Approved Products

Pipeline by Development Stage

Preclinical
Phase 1
Phase 1/2
Phase 2
Phase 2/3
Phase 3
On Market
0
0
0
0
0
1
0
Early DiscoveryClinical DevelopmentMarket

Competitive Landscape

1 companies ranked by most advanced pipeline stage

BioMarin Pharmaceutical
3 programs
1
BMN 110 - WeeklyPhase 31 trial
Elosulfase Alfa 1 MG/ML Intravenous Solution [VIMIZIM]N/A1 trial
Enzyme testingN/A1 trial
Active Trials
NCT03204370Completed7Est. Sep 2025
NCT01707433Completed22Est. Jun 2015
NCT01415427Completed173Est. Jun 2016

Trial Timeline

Clinical trial activity over time

2021
2022
2023
2024
2025
2026
BioMarin PharmaceuticalBMN 110 - Weekly
BioMarin PharmaceuticalElosulfase Alfa 1 MG/ML Intravenous Solution [VIMIZIM]
BioMarin PharmaceuticalEnzyme testing

Clinical Trials (3)

Total enrollment: 202 patients across 3 trials

Long-Term Efficacy and Safety Extension Study of BMN 110 in Patients With Mucopolysaccharidosis IVA (Morquio A Syndrome)

Start: Jul 2011Est. completion: Jun 2016173 patients
Phase 3Completed
NCT03204370BioMarin PharmaceuticalElosulfase Alfa 1 MG/ML Intravenous Solution [VIMIZIM]

Natural History of Atypical Morquio A Disease

Start: Feb 2018Est. completion: Sep 20257 patients
N/ACompleted

Diagnosis of Mucopolysaccharidosis Disorders in Patients Presenting With Bilateral Hip Disease

Start: Oct 2012Est. completion: Jun 201522 patients
N/ACompleted

Phase Legend

PreclinicalLab & animal studies
Phase 1Safety & dosing
Phase 2Efficacy testing
Phase 3Large-scale trials
On MarketApproved & available

Key Insights

1 late-stage (Phase 3) programs — potential near-term approvals
1 companies competing in this space