MPS IIIA

4
Pipeline Programs
2
Companies
2
Clinical Trials
1 recruiting
0
Approved Products

Pipeline by Development Stage

Preclinical
Phase 1
Phase 1/2
Phase 2
Phase 2/3
Phase 3
On Market
0
0
2
0
2
0
0
Early DiscoveryClinical DevelopmentMarket

Competitive Landscape

2 companies ranked by most advanced pipeline stage

Ultragenyx Pharmaceutical
2 programs
1
1
UX111Phase 2/3
ABO-102Phase 1/2
Abeona Therapeutics
Abeona TherapeuticsCLEVELAND, OH
2 programs
1
1
UX111Phase 2/31 trial
ABO-102Phase 1/21 trial
Active Trials
NCT04088734Terminated5Est. Mar 2022
NCT02716246Recruiting36Est. Jul 2027

Trial Timeline

Clinical trial activity over time

2021
2022
2023
2024
2025
2026
2027
Abeona TherapeuticsUX111
Abeona TherapeuticsABO-102

Clinical Trials (2)

Total enrollment: 41 patients across 2 trials

Phase I/II/III Gene Transfer Clinical Trial of scAAV9.U1a.hSGSH

Start: Apr 2016Est. completion: Jul 202736 patients
Phase 2/3Recruiting

Gene Transfer Study of ABO-102 in Patients With Middle and Advanced Phases of MPS IIIA Disease

Start: Sep 2019Est. completion: Mar 20225 patients
Phase 1/2Terminated

Phase Legend

PreclinicalLab & animal studies
Phase 1Safety & dosing
Phase 2Efficacy testing
Phase 3Large-scale trials
On MarketApproved & available

Key Insights

1 actively recruiting trials targeting 41 patients
2 companies competing in this space