Mitral Regurgitation

0
Pipeline Programs
2
Companies
9
Clinical Trials
5 recruiting
0
Approved Products

Pipeline by Development Stage

Preclinical
Phase 1
Phase 1/2
Phase 2
Phase 2/3
Phase 3
On Market
0
0
0
0
0
0
0
Early DiscoveryClinical DevelopmentMarket

Competitive Landscape

2 companies ranked by most advanced pipeline stage

Abbott
AbbottABBOTT PARK, IL
8 programs
Abbott Cephea Mitral Valve Disease RegistryN/A1 trial
Abbott SJM Rigid Saddle RingN/A1 trial
Cephea Mitral Valve SystemN/A1 trial
Cephea Mitral Valve SystemN/A1 trial
HERMES tabletN/A1 trial
+3 more programs
Active Trials
NCT07069673Recruiting1,000Est. Dec 2028
NCT04761120Recruiting550Est. Mar 2031
NCT05061004Recruiting50Est. Mar 2031
+5 more trials
FP
Fosun PharmaAustralia - Sydney
1 program
ultrasonic cardiographyN/A1 trial
Active Trials
NCT06162780Recruiting160Est. Dec 2026

Trial Timeline

Clinical trial activity over time

2021
2022
2023
2024
2025
2026
2027
2028
2029
2030
2031
AbbottAbbott Cephea Mitral Valve Disease Registry
AbbottCephea Mitral Valve System
Fosun Pharmaultrasonic cardiography
AbbottCephea Mitral Valve System
AbbottAbbott SJM Rigid Saddle Ring
AbbottTranscatheter mitral valve repair
AbbottTendyne Mitral Valve System
AbbottMitraClip® NT System
AbbottHERMES tablet

Clinical Trials (9)

Total enrollment: 2,182 patients across 9 trials

NCT07069673AbbottAbbott Cephea Mitral Valve Disease Registry

Abbott Cephea Mitral Valve Disease Registry

Start: Aug 2025Est. completion: Dec 20281,000 patients
N/ARecruiting
NCT07244939AbbottCephea Mitral Valve System

Cephea South America Feasibility Study

Start: Jun 2025Est. completion: Sep 202820 patients
N/ARecruiting
NCT06162780Fosun Pharmaultrasonic cardiography

TEER for Severe DMR of Low to Intermediate Surgery Risk

Start: Jan 2024Est. completion: Dec 2026160 patients
N/ARecruiting
NCT05061004AbbottCephea Mitral Valve System

Cephea Early Feasibility Study

Start: Apr 2022Est. completion: Mar 203150 patients
N/ARecruiting
NCT04761120AbbottAbbott SJM Rigid Saddle Ring

Annuloplasty Rings and Band Post-Market Clinical Follow-Up Study

Start: Feb 2021Est. completion: Mar 2031550 patients
N/ARecruiting
NCT03705312AbbottTranscatheter mitral valve repair

MitraClip for the Treatment of Moderate Functional Mitral Regurgitation: EVOLVE-MR

Start: Feb 2019Est. completion: Jan 2022174 patients
N/AUnknown
NCT03539458AbbottTendyne Mitral Valve System

Feasibility Study of the Tendyne Mitral Valve System in Mitral Annular Calcification

Start: Oct 2018Est. completion: Jun 202411 patients
N/ACompleted
NCT07227675AbbottMitraClip® NT System

Cardiovascular Outcomes Assessment of the MitraClip Percutaneous Therapy for Heart Failure Patients With Functional MR

Start: Oct 2017Est. completion: Mar 2024162 patients
N/ACompleted
NCT02698150AbbottHERMES tablet

Remote Monitoring of Patients With Functional Mitral Regurgitation Undergoing Mitraclip Transcatheter Repair

Start: Mar 2016Est. completion: Oct 201855 patients
N/AUnknown

Phase Legend

Preclinical— Lab & animal studies
Phase 1— Safety & dosing
Phase 2— Efficacy testing
Phase 3— Large-scale trials
On Market— Approved & available

Key Insights

5 actively recruiting trials targeting 2,182 patients
2 companies competing in this space