Mitral Regurgitation
Pipeline by Development Stage
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24 companies ranked by most advanced pipeline stage
Trial Timeline
Clinical trial activity over time
Showing 15 of 49 trials with date data
Clinical Trials (49)
Total enrollment: 8,192 patients across 49 trials
(MitraClip in Non-Responders to Cardiac Resynchronization Therapy)
A Clinical Study Evaluating the Replacement of the Native Mitral Valve Using the ReValve System
Mitral Insufficiency Reduction With Biventricular Pacing
ALLIANCE Mitral: Safety and Effectiveness of SAPIEN X4 Transcatheter Heart Valve - Mitral
Mitral Valve Repair With the Chord-X System: A Long Term Evaluation
EFS of Posterior Leaflet Replacement to Reduce Mitral Regurgitation (United States)
Reduction of Elimination of Mitral Regurgitation With the SATURN TMVR System (CASSINI-US)
Abbott Cephea Mitral Valve Disease Registry
Cephea South America Feasibility Study
Sutra Hemi-valve First-in-Human Study
Capstan Medical TMVR Study: FIH
AltaValve Pivotal Trial
Feasibility Study of the Tioga TMVR System
TEER for Severe DMR of Low to Intermediate Surgery Risk
Early Discharge After Mitral and Tricuspid Edge-to-edge Repair: an Assessment of Feasibility and Safety
Transcatheter Mitral Valve Replacement in Patients With Severe Symptomatic Mitral Regurgitation - APOLLO-EU Trial
Safety and Efficacy of the GeminiOne Transcatheter Valve Edge-to-Edge Repair System in Patients With Moderate-severe or Severe Degenerative Mitral Regurgitation
Safety and Efficacy of the HighLife Transcatherter Mitral Valve Replacement System in Patients With Moderate-severe or Severe Mitral Regurgitation in China
Cephea Early Feasibility Study
Structural Mitral Valve Project
MitraClip China PMS
Carillon Mitral Contour System for Treatment of Exercise Induced Functional Mitral Regurgitation
Mi-STITCH™ and Mi-KNOT™ Device Technologies - Improvement of Mitral Valve Repair
EFS of the CardioMech MVRS
Annuloplasty Rings and Band Post-Market Clinical Follow-Up Study
In Search of Best Practices for Patients With Heart Failure and Secondary Mitral Regurgitation: An Evaluation of the Inova Heart Failure Treatment Algorithm
Beating Heart Mitral Valve Repair With the HARPOON™ System
The ENCIRCLE Trial
CHoice of OptImal transCatheter trEatment for Mitral Insufficiency Registry
Treatment of Mitral Regurgitation Using a Minimally Invasive Approach With the HARPOON Device.
SATURN Transcatheter Mitral Valve Replacement for Functional Mitral Regurgitation
Multicenter Post-Market Observational Registry of the NeoChord Artificial Chordae Delivery System
Early Feasibility EXperience of Posterior Leaflet RestOration to REduce Mitral Regurgitation
AltaValve Early Feasibility Study Protocol
MitraClip for the Treatment of Moderate Functional Mitral Regurgitation: EVOLVE-MR
Feasibility Study of the Tendyne Mitral Valve System in Mitral Annular Calcification
Clinical Trial to Evaluate the Safety and Effectiveness of Using the Tendyne Transcatheter Mitral Valve System for the Treatment of Symptomatic Mitral Regurgitation
Edwards Cardioband European Post-Market Study, MiBAND
MitraClip NT System Post-marketing Surveillance Study - Japan
Epicardial Mitral Repair Trial - ENRAPT-MR
Cardiovascular Outcomes Assessment of the MitraClip Percutaneous Therapy for Heart Failure Patients With Functional MR
SAPIEN M3 EFS: Early Feasibility Study of the Edwards SAPIEN M3 System for the Treatment of Mitral Regurgitation
MitraClip in Acute Mitral Regurgitation
Remote Monitoring of Patients With Functional Mitral Regurgitation Undergoing Mitraclip Transcatheter Repair
AMENDTM Mitral Valve Repair System, Annuloplasty Ring Applied in a Transcatheter Method
Cardiovascular Outcomes Assessment of the MitraClip Percutaneous Therapy for Heart Failure Patients With Functional Mitral Regurgitation (The COAPT Trial) and COAPT CAS
MitraClip System in Australia and New Zealand
Cardioband With Transfemoral Delivery System
A Study of Percutaneous Repair of Functional Mitral Regurgitation Using the Ancora Heart, Inc. AccuCinch® Ventricular Repair System - The CINCH-2 Study
Phase Legend
Key Insights
The information on this page is for informational purposes only and should not be used as a substitute for professional medical advice. Drug information is sourced from FDA, DailyMed, and other government databases. Adverse event data from FAERS does not establish causation. Always consult a healthcare professional for medical decisions.