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Medulloblastoma, Childhood

3
Pipeline Programs
4
Companies
3
Clinical Trials
0
Approved Products

Pipeline by Development Stage

Preclinical
Phase 1
Phase 1/2
Phase 2
Phase 2/3
Phase 3
On Market
0
1
2
0
0
0
0
Early DiscoveryClinical DevelopmentMarket

Drug Modality Breakdown

Monoclonal Antibody
1100%
+ 2 programs with unclassified modality

Competitive Landscape

3 companies ranked by most advanced pipeline stage

Y-mAbs Therapeutics
Y-mAbs TherapeuticsNY - New York
1 program
1
177Lu-DTPA-omburtamabPhase 1/2Monoclonal Antibody1 trial
Active Trials
NCT04167618Terminated2Est. Aug 2022
Senhwa Biosciences
Senhwa BiosciencesCA - San Diego
1 program
1
CX 4945Phase 1/21 trial
Active Trials
NCT03904862Terminated21Est. Aug 2025
Prevail Therapeutics
1 program
1
LY2940680Phase 11 trial
Active Trials
NCT01697514Withdrawn0Est. Jul 2016

Trial Timeline

Clinical trial activity over time

2021
2022
2023
2024
2025
2026
Y-mAbs Therapeutics177Lu-DTPA-omburtamab
Senhwa BiosciencesCX 4945
Prevail TherapeuticsLY2940680

Clinical Trials (3)

Total enrollment: 23 patients across 3 trials

NCT04167618Y-mAbs Therapeutics177Lu-DTPA-omburtamab

177Lu-DTPA-Omburtamab Radioimmunotherapy for Recurrent or Refractory Medulloblastoma

Start: Sep 2021Est. completion: Aug 20222 patients
Phase 1/2Terminated

Testing the Safety and Tolerability of CX-4945 in Patients With Recurrent Medulloblastoma Who May or May Not Have Surgery

Start: Jul 2019Est. completion: Aug 202521 patients
Phase 1/2Terminated

A Study of LY2940680 in Pediatric Medulloblastoma or Rhabdomyosarcoma

Start: Jul 2013Est. completion: Jul 20160
Phase 1Withdrawn

Phase Legend

PreclinicalLab & animal studies
Phase 1Safety & dosing
Phase 2Efficacy testing
Phase 3Large-scale trials
On MarketApproved & available

Key Insights

4 companies competing in this space

The information on this page is for informational purposes only and should not be used as a substitute for professional medical advice. Drug information is sourced from FDA, DailyMed, and other government databases. Adverse event data from FAERS does not establish causation. Always consult a healthcare professional for medical decisions.