Mature B-cell Malignancies

3
Pipeline Programs
2
Companies
3
Clinical Trials
1 recruiting
0
Approved Products

Pipeline by Development Stage

Preclinical
Phase 1
Phase 1/2
Phase 2
Phase 2/3
Phase 3
On Market
0
2
1
0
0
0
0
Early DiscoveryClinical DevelopmentMarket

Drug Modality Breakdown

Small Molecule
1100%
+ 2 programs with unclassified modality

Competitive Landscape

2 companies ranked by most advanced pipeline stage

BeOne Medicines
BeOne MedicinesCA - San Carlos
2 programs
1
1
ZanubrutinibPhase 1/2Small Molecule1 trial
BGB-11417Phase 11 trial
Active Trials
NCT04883957Active Not RecruitingEst. Apr 2026
NCT04172246CompletedEst. Jun 2025
InnoCare
InnoCareChina - Beijing
1 program
1
ICP-248Phase 11 trial
Active Trials
NCT06351527Recruiting78Est. Oct 2027

Trial Timeline

Clinical trial activity over time

2021
2022
2023
2024
2025
2026
2027
BeOne MedicinesZanubrutinib
InnoCareICP-248
BeOne MedicinesBGB-11417

Clinical Trials (3)

Total enrollment: 78 patients across 3 trials

Study of Zanubrutinib in Japanese Participants With B-Cell Malignancies

Start: Jan 2020Est. completion: Jun 2025
Phase 1/2Completed

Evaluate the Safety, Tolerability, Pharmacokinetics, and Preliminary Efficacy of ICP-248 as Monotherapy or in Combination With Anti-CD20 Monoclonal Antibody in Mature B-cell Malignancies

Start: Apr 2024Est. completion: Oct 202778 patients
Phase 1Recruiting

Study of BGB-11417 in Adult Participants With Mature B-cell Malignancies

Start: Jul 2021Est. completion: Apr 2026
Phase 1Active Not Recruiting

Phase Legend

PreclinicalLab & animal studies
Phase 1Safety & dosing
Phase 2Efficacy testing
Phase 3Large-scale trials
On MarketApproved & available

Key Insights

1 actively recruiting trials targeting 78 patients
2 companies competing in this space