MASH

1
Pipeline Programs
3
Companies
2
Clinical Trials
1 recruiting
0
Approved Products

Pipeline by Development Stage

Preclinical
Phase 1
Phase 1/2
Phase 2
Phase 2/3
Phase 3
On Market
0
0
0
0
0
1
0
Early DiscoveryClinical DevelopmentMarket

Drug Modality Breakdown

Small Molecule
1100%
+ 2 programs with unclassified modality

Competitive Landscape

3 companies ranked by most advanced pipeline stage

Sagimet Biosciences
Sagimet BiosciencesCA - San Mateo
1 program
1
DenifanstatPhase 3Small Molecule1 trial
Active Trials
NCT06594523WithdrawnEst. Dec 2030
Inventiva
InventivaDAIX, France
1 program
Global Research Initiative for Patients Screening on MASHN/A
Novo Nordisk
Novo NordiskBAGSVAERD DENMARK, Denmark
1 program
Global Research Initiative for Patients Screening on MASHN/A1 trial
Active Trials
NCT05651724Recruiting10,000Est. Mar 2031

Trial Timeline

Clinical trial activity over time

2023
2024
2025
2026
2027
2028
2029
2030
2031
Sagimet BiosciencesDenifanstat
Novo NordiskGlobal Research Initiative for Patients Screening on MASH

Clinical Trials (2)

Total enrollment: 10,000 patients across 2 trials

A Phase 3 Study Evaluating the Safety and Efficacy of Denifanstat in Patients With MASH and F2/F3 Fibrosis

Start: Mar 2025Est. completion: Dec 2030
Phase 3Withdrawn
NCT05651724Novo NordiskGlobal Research Initiative for Patients Screening on MASH

Global Research Initiative for Patients Screening on MASH

Start: Jun 2023Est. completion: Mar 203110,000 patients
N/ARecruiting

Phase Legend

PreclinicalLab & animal studies
Phase 1Safety & dosing
Phase 2Efficacy testing
Phase 3Large-scale trials
On MarketApproved & available

Key Insights

1 late-stage (Phase 3) programs — potential near-term approvals
1 actively recruiting trials targeting 10,000 patients
3 companies competing in this space