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Malocclusion

0
Pipeline Programs
2
Companies
6
Clinical Trials
1 recruiting
0
Approved Products

Pipeline by Development Stage

Preclinical
Phase 1
Phase 1/2
Phase 2
Phase 2/3
Phase 3
On Market
0
0
0
0
0
0
0
Early DiscoveryClinical DevelopmentMarket

Competitive Landscape

2 companies ranked by most advanced pipeline stage

Align Technology
4 programs
InvisalignN/A3 trials
InvisalignN/A1 trial
Invisalign SystemN/A
Movement Enhancement TechniqueN/A1 trial
Active Trials
NCT06662279Recruiting36Est. Jan 2026
NCT02603289Completed287Est. Aug 2020
NCT02376829Completed164Est. Nov 2021
+2 more trials
Solventum
SolventumMN - St. Paul
1 program
Clear AlignerN/A1 trial
Active Trials
NCT03141788Completed52Est. Oct 2019

Trial Timeline

Clinical trial activity over time

2021
2022
2023
2024
2025
2026
Align TechnologyInvisalign
SolventumClear Aligner
Align TechnologyInvisalign
Align TechnologyInvisalign
Align TechnologyInvisalign
Align TechnologyMovement Enhancement Technique

Clinical Trials (6)

Total enrollment: 882 patients across 6 trials

NCT06662279Align TechnologyInvisalign

Hyrax Vs. Invisalign Palatal Expander Clinical Study

Start: Oct 2024Est. completion: Jan 202636 patients
N/ARecruiting
NCT03141788SolventumClear Aligner

Evaluation of Clear Aligner Trays to Straighten Teeth

Start: Jan 2017Est. completion: Oct 201952 patients
N/ACompleted
NCT02603289Align TechnologyInvisalign

One Week Aligner Evaluation

Start: Sep 2015Est. completion: Aug 2020287 patients
N/ACompleted
NCT02550938Align TechnologyInvisalign

Primer Aligner Study

Start: May 2015Est. completion: Sep 2020253 patients
N/ACompleted
NCT02376829Align TechnologyInvisalign

Class II Correction Study Using the Invisalign System

Start: Mar 2015Est. completion: Nov 2021164 patients
N/ACompleted
NCT02087163Align TechnologyMovement Enhancement Technique

The Use of Clear Aligners With Movement Enhancement Techniques

Start: Feb 2014Est. completion: Apr 201990 patients
N/ACompleted

Phase Legend

Preclinical— Lab & animal studies
Phase 1— Safety & dosing
Phase 2— Efficacy testing
Phase 3— Large-scale trials
On Market— Approved & available

Key Insights

1 actively recruiting trials targeting 882 patients
2 companies competing in this space

The information on this page is for informational purposes only and should not be used as a substitute for professional medical advice. Drug information is sourced from FDA, DailyMed, and other government databases. Adverse event data from FAERS does not establish causation. Always consult a healthcare professional for medical decisions.