Malnutrition

Pipeline Programs

Companies

Clinical Trials

3 recruiting

Approved Products

Pipeline by Development Stage

Preclinical

Phase 1

Phase 1/2

Phase 2

Phase 2/3

Phase 3

On Market

Early DiscoveryClinical DevelopmentMarket

Drug Modality Breakdown

Small Molecule

1100%

+ 41 programs with unclassified modality

Competitive Landscape

17 companies ranked by most advanced pipeline stage

Pre

P1/2

P2/3

Mkt

AbbottABBOTT PARK, IL

12 programs

Nepro with Carb SteadyPhase 41 trial

Nutritional beverage 10003RFPhase 31 trial

medical food with AN777Phase 31 trial

A Nutrition-Focused QIP in Outpatient ClinicsN/A1 trial

A Nutrition-Focused Quality Improvement Program in Hospitalized Malnourished PatientsN/A1 trial

+7 more programs

Active Trials

NCT03628196Completed1,800Est. Mar 2020

NCT03679832Completed1,670Est. Oct 2019

NCT02052232Completed39Est. Apr 2015

+9 more trials

SandozAustria - Kundl

1 program

ImpactPhase 42 trials

Active Trials

NCT07508007Recruiting4,500Est. Mar 2028

NCT00333099Completed250Est. Sep 2011

Selva TherapeuticsCA - Del Mar

1 program

MebendazolePhase 4Small Molecule1 trial

Active Trials

NCT01314937Completed1,760Est. Jul 2013

Pediatrix TherapeuticsChina - Shanghai

1 program

Parenteral NutritionPhase 31 trial

Active Trials

NCT00120926Completed150Est. Jun 2006

Human BioSciencesWV - Martinsburg

5 programs

Canned HerringN/A1 trial

ChispuditosN/A1 trial

Personalized informationN/A1 trial

Treatment 1: ControlN/A1 trial

Wetting methodN/A1 trial

Active Trials

NCT02496247Completed1,200Est. Aug 2015

NCT01303016Unknown639Est. Dec 2011

NCT02903641Completed506Est. Sep 2016

+2 more trials

Fresenius KabiGermany - Bad Homburg

5 programs

Fresubin® powder fibreN/A1 trial

High caloric, high protein ONSN/A1 trial

Intradialytic Parenteral NutritionPHASE_41 trial

Kabiven®PHASE_41 trial

Active Trials

NCT04474886Completed88Est. Feb 2022

NCT02938247Completed20Est. Oct 2016

NCT02938234Completed20Est. Oct 2016

+2 more trials

UNION therapeuticsDenmark - Hellerup

4 programs

Nutrition Support on Outcomes and Cost-effectiveness for Patients at RiskN/A1 trial

The Impact of Perioperational Malnutrition on the Cost on Gastroenterological Cancer PatientsN/A1 trial

The school feeding interventionN/A1 trial

nutritional supportN/A1 trial

Active Trials

NCT00289380Recruiting2,000Est. Jan 2040

NCT00987883Unknown200Est. Dec 2009

NCT03263377Completed3,006Est. Jun 2013

+1 more trials

Oregon TherapeuticsFrance - Paris

2 programs

Childhood Acute Illness and Nutrition NetworkN/A1 trial

Continuous Tube FeedingsN/A1 trial

Active Trials

NCT03208725Unknown4,335Est. Oct 2020

NCT01383980Completed36Est. Aug 2017

BaxterCosta Rica - Cartago

2 programs

Measure of quadriceps thickness with ultrasonography and albumin/prealbumin levelsN/A

Parenteral NutritionN/A

Baxter InternationalDEERFIELD, IL

2 programs

Measure of quadriceps thickness with ultrasonography and albumin/prealbumin levelsN/A1 trial

Parenteral NutritionN/A1 trial

Active Trials

NCT02564159Terminated286Est. Aug 2022

NCT03926949Recruiting60Est. Jul 2026

Brixton BiosciencesMA - Cambridge

1 program

Click-MUAC prototype & regular MUAC tapeN/A1 trial

Active Trials

NCT02833740Unknown345Est. Apr 2017

Innovation PharmaceuticalsMA - Wakefield

1 program

Click-MUAC prototype & regular MUAC tapeN/A

BraccoItaly - Milan

1 program

Homestead Food Production programN/A

Heidelberg PharmaGermany - Ladenburg

1 program

Homestead Food Production programN/A1 trial

Active Trials

NCT02505711Completed2,705Est. Aug 2021

BiocorpFrance - Issoire

1 program

Nutritional statusN/A1 trial

Active Trials

NCT03926715Unknown700Est. Dec 2019

Alliance PharmaceuticalsUK - Wiltshire

1 program

Screening by mothersN/A1 trial

Active Trials

NCT01863394Completed4,429Est. Apr 2014

NovartisBASEL, Switzerland

1 program

ImpactPHASE_4

Trial Timeline

Clinical trial activity over time

2021

2022

2023

2024

2025

2026

2027

2028

2029

2030

2031

Fresenius KabiKabiven®

Selva TherapeuticsMebendazole

AbbottNepro with Carb Steady

SandozImpact

Fresenius KabiIntradialytic Parenteral Nutrition

Abbottmedical food with AN777

AbbottNutritional beverage 10003RF

Pediatrix TherapeuticsParenteral Nutrition

UNION therapeuticsnutritional support

SandozImpact

Human BioSciencesWetting method

Fresenius KabiFresubin® powder fibre

Baxter InternationalParenteral Nutrition

AbbottNutrition-Focused Quality Improvement Program (QIP) Among Community Dwelling Malnourished Patients

AbbottA Nutrition-Focused Quality Improvement Program in Hospitalized Malnourished Patients

Showing 15 of 38 trials with date data

Clinical Trials (38)

Total enrollment: 40,763 patients across 38 trials

NCT03481894 Fresenius KabiKabiven®

Study to Assess Safety and Efficacy of Kabiven® in Pediatric Patients 2 to 16 Years of Age

Start: Mar 2018Est. completion: Mar 20210

Phase 4Withdrawn

NCT01314937 Selva TherapeuticsMebendazole

The Effect of a Deworming Intervention to Improve Early Childhood Growth and Development in Resource-poor Areas

Start: Sep 2011Est. completion: Jul 20131,760 patients

Phase 4Completed

NCT00895401 AbbottNepro with Carb Steady

DaVita Assessment of Nutritional Supplement Effects (DANSE)

Start: Apr 2009160 patients

Phase 4Completed

NCT00333099 SandozImpact

INEC Study: Immuno-modulating Enteral Nutrition in Cancer

Start: May 2006Est. completion: Sep 2011250 patients

Phase 4Completed

NCT00501956 Fresenius KabiIntradialytic Parenteral Nutrition

Intradialytic Parenteral Nutrition in Hemodialysis Patients

Start: Jul 2004Est. completion: Dec 2010140 patients

Phase 4Completed

NCT01191125 Abbottmedical food with AN777

Evaluation of an Oral Nutritional Supplement Containing AN777

Start: Feb 2011Est. completion: Sep 2012331 patients

Phase 3Completed

NCT01641770 AbbottNutritional beverage 10003RF

Oral Nutritional Supplementation in Hospital Patients

Start: Oct 2010Est. completion: Oct 2011212 patients

Phase 3Completed

NCT00120926 Pediatrix TherapeuticsParenteral Nutrition

Dose Comparison of Amino Acids on Growth in Premature Neonates

Start: Aug 2005Est. completion: Jun 2006150 patients

Phase 3Completed

NCT05917418 UNION therapeuticsnutritional support

Nutritional Support on Outcomes and Cost-effectiveness for Patients at Risk

Start: Dec 2026Est. completion: Jan 2040400 patients

N/ANot Yet Recruiting

NCT07508007 SandozImpact

Impact of Implementation Strategies on Lp(a) Testing in Secondary Care Settings

Start: Nov 2025Est. completion: Mar 20284,500 patients

N/ARecruiting

NCT04036708 Human BioSciencesWetting method

Caregiver Training to Prevent Konzo Disease in Children in Democratic Republic of Congo (DRC)

Start: Apr 2021Est. completion: Aug 2022238 patients

N/ACompleted

NCT04474886 Fresenius KabiFresubin® powder fibre

Oral Nutritional Supplement for the Patient With or at Risk of Malnutrition

Start: Nov 2020Est. completion: Feb 202288 patients

N/ACompleted

NCT03926949 Baxter InternationalParenteral Nutrition

Outpatient Preoperative Parenteral Nutrition in Malnourished Surgical Patients

Start: Oct 2019Est. completion: Jul 202660 patients

N/ARecruiting

NCT04042987 AbbottNutrition-Focused Quality Improvement Program (QIP) Among Community Dwelling Malnourished Patients

Nutrition-Focused Quality Improvement Program (QIP) Among Community Dwelling Malnourished Patients

Start: Sep 2019Est. completion: Jun 20201,325 patients

N/ACompleted

NCT03679832 AbbottA Nutrition-Focused Quality Improvement Program in Hospitalized Malnourished Patients

A Nutrition-Focused Quality Improvement Program in Hospitalized Malnourished Patients

Start: Mar 2019Est. completion: Oct 20191,670 patients

N/ACompleted

NCT03628196 AbbottA Nutrition-Focused QIP in Outpatient Clinics

A Nutrition-Focused QIP in Outpatient Clinics

Start: Sep 2018Est. completion: Mar 20201,800 patients

N/ACompleted

NCT03459001 AbbottTube Feeding Product

Evaluation of a High Calorie, High Protein Tube Feeding Product in an Adult Population With or at Risk of Malnutrition

Start: Jun 2018Est. completion: Feb 201917 patients

N/ACompleted

NCT03240952 AbbottThe Nutritional Health for the Elderly Reference Centre Study (NHERC Study)

The Nutritional Health for the Elderly Reference Centre Study (NHERC Study)

Start: Aug 2017Est. completion: Jul 2018400 patients

N/ACompleted

NCT03926715 BiocorpNutritional status

Prevalence of Malnutrition in Surgery

Start: Jan 2017Est. completion: Dec 2019700 patients

N/AUnknown

NCT03011944 AbbottQuality Improvement Program

Impact of a Nutrition Quality Improvement Program on Outcomes of Malnourished Patients

Start: Dec 2016Est. completion: Mar 20181,546 patients

N/ACompleted

NCT03208725 Oregon TherapeuticsChildhood Acute Illness and Nutrition Network

Childhood Acute Illness and Nutrition Network

Start: Nov 2016Est. completion: Oct 20204,335 patients

N/AUnknown

NCT02938234 Fresenius KabiHigh caloric, high protein ONS

Tolerance and Compliance of a High Caloric, High Protein Oral Nutritional Supplement - Free Intake

Start: Sep 2016Est. completion: Oct 201620 patients

N/ACompleted

NCT02833740 Brixton BiosciencesClick-MUAC prototype & regular MUAC tape

Comparing Performance of Simplified Mid-Upper Arm Circumference Devices ("Click-MUACs") to Detect Acute Malnutrition

Start: Sep 2016Est. completion: Apr 2017345 patients

N/AUnknown

NCT02938247 Fresenius KabiHigh caloric, high protein ONS

Tolerance and Compliance of a High Caloric, High Protein Oral Nutritional Supplement - Scheduled Intake

Start: Sep 2016Est. completion: Oct 201620 patients

N/ACompleted

NCT02903641 Human BioSciencesPersonalized information

Money or Knowledge? Behavioral Aspects of Malnutrition

Start: Jul 2016Est. completion: Sep 2016506 patients

N/ACompleted

NCT02564159 Baxter InternationalMeasure of quadriceps thickness with ultrasonography and albumin/prealbumin levels

Malnutrition Screening by Muscle Ultrasound in Patients Requiring Mechanical Ventilation in Intensive Care Unit

Start: Oct 2015Est. completion: Aug 2022286 patients

N/ATerminated

NCT02464111 Human BioSciencesTreatment 1: Control

Short Term Response of Breast Milk Micronutrient Concentrations to a Lipid Based Nutrient Supplement in Guatemalan Women

Start: May 2015Est. completion: Aug 201530 patients

N/ACompleted

NCT02496247 Human BioSciencesCanned Herring

Canned Herring for Prevention of Childhood Malnutrition During the Early Rainy Season in Rural Guinea-Bissau

Start: May 2015Est. completion: Aug 20151,200 patients

N/ACompleted

NCT02505711 Heidelberg PharmaHomestead Food Production program

Food and Agricultural Approaches to Reducing Malnutrition

Start: Mar 2015Est. completion: Aug 20212,705 patients

N/ACompleted

NCT02262429 AbbottONS QIP

Quality Improvement Program (QIP) to Reduce 30-Day Readmission in Malnourished Hospitalized Patients

Start: Oct 2014Est. completion: Aug 20152,386 patients

N/ATerminated

NCT02089906 AbbottHealth and Nutrition Status of Chinese Elderly

Health and Nutrition Status of Chinese Elderly

Start: Mar 2014Est. completion: Jul 20152,834 patients

N/ACompleted

NCT02052232 AbbottExperimental protein powder sachet

Study of Protein Metabolism in Healthy Older Subjects

Start: Mar 2014Est. completion: Apr 201539 patients

N/ACompleted

NCT01863394 Alliance PharmaceuticalsScreening by mothers

Evaluation of Two Community Based Screening Strategies for Severe Acute Malnutrition in Children 6-59 Months in Mirria District, Niger

Start: May 2013Est. completion: Apr 20144,429 patients

N/ACompleted

NCT03263377 UNION therapeuticsThe school feeding intervention

The Impact on School Feeding on Children's Growth and Development

Start: Sep 2011Est. completion: Jun 20133,006 patients

N/ACompleted

NCT01383980 Oregon TherapeuticsContinuous Tube Feedings

Trial of Continuous Versus Interrupted Feeding for Intubated Intensive Care Unit Patients

Start: Aug 2011Est. completion: Aug 201736 patients

N/ACompleted

NCT01303016 Human BioSciencesChispuditos

Improving Nutrition and Health Outcomes in Intibuca, Honduras

Start: May 2010Est. completion: Dec 2011639 patients

N/AUnknown

NCT00987883 UNION therapeuticsThe Impact of Perioperational Malnutrition on the Cost on Gastroenterological Cancer Patients

The Impact of Perioperational Malnutrition on the Cost on Gastroenterological Cancer Patients

Start: Apr 2009Est. completion: Dec 2009200 patients

N/AUnknown

NCT00289380 UNION therapeuticsNutrition Support on Outcomes and Cost-effectiveness for Patients at Risk

Nutrition Support on Outcomes and Cost-effectiveness for Patients at Risk

Start: Jan 2005Est. completion: Jan 20402,000 patients

N/ARecruiting

Phase Legend

Preclinical— Lab & animal studies

Phase 1— Safety & dosing

Phase 2— Efficacy testing

Phase 3— Large-scale trials

On Market— Approved & available

Key Insights

3 late-stage (Phase 3) programs, potential near-term approvals

3 actively recruiting trials targeting 40,763 patients

20 companies competing in this space

The information on this page is for informational purposes only and should not be used as a substitute for professional medical advice. Drug information is sourced from FDA, DailyMed, and other government databases. Adverse event data from FAERS does not establish causation. Always consult a healthcare professional for medical decisions.