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Malnutrition

6
Pipeline Programs
20
Companies
49
Clinical Trials
3 recruiting
0
Approved Products

Pipeline by Development Stage

Preclinical
Phase 1
Phase 1/2
Phase 2
Phase 2/3
Phase 3
On Market
0
0
0
0
0
3
3
Early DiscoveryClinical DevelopmentMarket

Drug Modality Breakdown

Small Molecule
1100%
+ 41 programs with unclassified modality

Competitive Landscape

17 companies ranked by most advanced pipeline stage

Abbott
AbbottABBOTT PARK, IL
12 programs
2
1
Nepro with Carb SteadyPhase 41 trial
Nutritional beverage 10003RFPhase 31 trial
medical food with AN777Phase 31 trial
A Nutrition-Focused QIP in Outpatient ClinicsN/A1 trial
A Nutrition-Focused Quality Improvement Program in Hospitalized Malnourished PatientsN/A1 trial
+7 more programs
Active Trials
NCT03628196Completed1,800Est. Mar 2020
NCT03679832Completed1,670Est. Oct 2019
NCT02052232Completed39Est. Apr 2015
+9 more trials
Sandoz
SandozAustria - Kundl
1 program
1
ImpactPhase 42 trials
Active Trials
NCT07508007Recruiting4,500Est. Mar 2028
NCT00333099Completed250Est. Sep 2011
Selva Therapeutics
Selva TherapeuticsCA - Del Mar
1 program
1
MebendazolePhase 4Small Molecule1 trial
Active Trials
NCT01314937Completed1,760Est. Jul 2013
Pediatrix Therapeutics
Pediatrix TherapeuticsChina - Shanghai
1 program
1
Parenteral NutritionPhase 31 trial
Active Trials
NCT00120926Completed150Est. Jun 2006
Human BioSciences
Human BioSciencesWV - Martinsburg
5 programs
Canned HerringN/A1 trial
ChispuditosN/A1 trial
Personalized informationN/A1 trial
Treatment 1: ControlN/A1 trial
Wetting methodN/A1 trial
Active Trials
NCT02496247Completed1,200Est. Aug 2015
NCT01303016Unknown639Est. Dec 2011
NCT02903641Completed506Est. Sep 2016
+2 more trials
Fresenius Kabi
Fresenius KabiGermany - Bad Homburg
5 programs
Fresubin® powder fibreN/A1 trial
High caloric, high protein ONSN/A1 trial
High caloric, high protein ONSN/A1 trial
Intradialytic Parenteral NutritionPHASE_41 trial
Kabiven®PHASE_41 trial
Active Trials
NCT04474886Completed88Est. Feb 2022
NCT02938234Completed20Est. Oct 2016
NCT02938247Completed20Est. Oct 2016
+2 more trials
UNION therapeutics
UNION therapeuticsDenmark - Hellerup
4 programs
Nutrition Support on Outcomes and Cost-effectiveness for Patients at RiskN/A1 trial
The Impact of Perioperational Malnutrition on the Cost on Gastroenterological Cancer PatientsN/A1 trial
The school feeding interventionN/A1 trial
nutritional supportN/A1 trial
Active Trials
NCT00289380Recruiting2,000Est. Jan 2040
NCT00987883Unknown200Est. Dec 2009
NCT03263377Completed3,006Est. Jun 2013
+1 more trials
Oregon Therapeutics
Oregon TherapeuticsFrance - Paris
2 programs
Childhood Acute Illness and Nutrition NetworkN/A1 trial
Continuous Tube FeedingsN/A1 trial
Active Trials
NCT03208725Unknown4,335Est. Oct 2020
NCT01383980Completed36Est. Aug 2017
Baxter International
2 programs
Measure of quadriceps thickness with ultrasonography and albumin/prealbumin levelsN/A
Parenteral NutritionN/A
Baxter
BaxterCosta Rica - Cartago
2 programs
Measure of quadriceps thickness with ultrasonography and albumin/prealbumin levelsN/A1 trial
Parenteral NutritionN/A5 trials
Active Trials
NCT02564159Terminated286Est. Aug 2022
NCT05439174Unknown1,200Est. Mar 2023
NCT04168749Unknown200Est. May 2020
+3 more trials
Brixton Biosciences
Brixton BiosciencesMA - Cambridge
1 program
Click-MUAC prototype & regular MUAC tapeN/A1 trial
Active Trials
NCT02833740Unknown345Est. Apr 2017
Innovation Pharmaceuticals
1 program
Click-MUAC prototype & regular MUAC tapeN/A
Bracco
BraccoItaly - Milan
1 program
Homestead Food Production programN/A
Heidelberg Pharma
Heidelberg PharmaGermany - Ladenburg
1 program
Homestead Food Production programN/A1 trial
Active Trials
NCT02505711Completed2,705Est. Aug 2021
Biocorp
BiocorpFrance - Issoire
1 program
Nutritional statusN/A1 trial
Active Trials
NCT03926715Unknown700Est. Dec 2019
Alliance Pharmaceuticals
1 program
Screening by mothersN/A1 trial
Active Trials
NCT01863394Completed4,429Est. Apr 2014
Novartis
NovartisBASEL, Switzerland
1 program
ImpactPHASE_4

Trial Timeline

Clinical trial activity over time

2021
2022
2023
2024
2025
2026
2027
2028
2029
2030
2031
Fresenius KabiKabiven®
Selva TherapeuticsMebendazole
AbbottNepro with Carb Steady
BaxterParenteral Nutrition
SandozImpact
Fresenius KabiIntradialytic Parenteral Nutrition
BaxterParenteral Nutrition
Abbottmedical food with AN777
AbbottNutritional beverage 10003RF
Pediatrix TherapeuticsParenteral Nutrition
BaxterParenteral Nutrition
UNION therapeuticsnutritional support
SandozImpact
BaxterParenteral Nutrition
Human BioSciencesWetting method

Showing 15 of 49 trials with date data

Clinical Trials (49)

Total enrollment: 48,147 patients across 49 trials

NCT03481894Fresenius KabiKabiven®

Study to Assess Safety and Efficacy of Kabiven® in Pediatric Patients 2 to 16 Years of Age

Start: Mar 2018Est. completion: Mar 20210
Phase 4Withdrawn
NCT01314937Selva TherapeuticsMebendazole

The Effect of a Deworming Intervention to Improve Early Childhood Growth and Development in Resource-poor Areas

Start: Sep 2011Est. completion: Jul 20131,760 patients
Phase 4Completed
NCT00895401AbbottNepro with Carb Steady

DaVita Assessment of Nutritional Supplement Effects (DANSE)

Start: Apr 2009160 patients
Phase 4Completed
NCT00512122BaxterParenteral Nutrition

Impact of Early Parenteral Nutrition Completing Enteral Nutrition in Adult Critically Ill Patients

Start: Aug 2007Est. completion: Dec 20264,640 patients
Phase 4Active Not Recruiting
NCT00333099SandozImpact

INEC Study: Immuno-modulating Enteral Nutrition in Cancer

Start: May 2006Est. completion: Sep 2011250 patients
Phase 4Completed
NCT00501956Fresenius KabiIntradialytic Parenteral Nutrition

Intradialytic Parenteral Nutrition in Hemodialysis Patients

Start: Jul 2004Est. completion: Dec 2010140 patients
Phase 4Completed
NCT01579097BaxterParenteral Nutrition

Comparative Phase 3 Trial to Assess the Safety and Efficacy of Triple-chamber Parenteral Nutrition Formulation

Start: Dec 2011Est. completion: Jan 2013458 patients
Phase 3Completed
NCT01191125Abbottmedical food with AN777

Evaluation of an Oral Nutritional Supplement Containing AN777

Start: Feb 2011Est. completion: Sep 2012331 patients
Phase 3Completed
NCT01641770AbbottNutritional beverage 10003RF

Oral Nutritional Supplementation in Hospital Patients

Start: Oct 2010Est. completion: Oct 2011212 patients
Phase 3Completed
NCT00120926Pediatrix TherapeuticsParenteral Nutrition

Dose Comparison of Amino Acids on Growth in Premature Neonates

Start: Aug 2005Est. completion: Jun 2006150 patients
Phase 3Completed
NCT04051840BaxterParenteral Nutrition

Safely and Efficacy of ClinOleic-based Lipid Parenteral Nutrition

Start: Jul 2017Est. completion: Jun 2020200 patients
Phase 1Unknown
NCT05917418UNION therapeuticsnutritional support

Nutritional Support on Outcomes and Cost-effectiveness for Patients at Risk

Start: Dec 2026Est. completion: Jan 2040400 patients
N/ANot Yet Recruiting
NCT07508007SandozImpact

Impact of Implementation Strategies on Lp(a) Testing in Secondary Care Settings

Start: Nov 2025Est. completion: Mar 20284,500 patients
N/ARecruiting
NCT05439174BaxterParenteral Nutrition

Impact of IDPN on Nutrition Markers in Patients Receiving ICHD

Start: Jul 2022Est. completion: Mar 20231,200 patients
N/AUnknown
NCT04036708Human BioSciencesWetting method

Caregiver Training to Prevent Konzo Disease in Children in Democratic Republic of Congo (DRC)

Start: Apr 2021Est. completion: Aug 2022238 patients
N/ACompleted
NCT04474886Fresenius KabiFresubin® powder fibre

Oral Nutritional Supplement for the Patient With or at Risk of Malnutrition

Start: Nov 2020Est. completion: Feb 202288 patients
N/ACompleted
NCT04168749BaxterParenteral Nutrition

Efficacy and Safety of Industrially Prepared 3 Chamber Bag Parenteral Nutrition for Premature Infant

Start: Nov 2019Est. completion: May 2020200 patients
N/AUnknown
NCT03926949BaxterParenteral Nutrition

Outpatient Preoperative Parenteral Nutrition in Malnourished Surgical Patients

Start: Oct 2019Est. completion: Jul 202660 patients
N/ARecruiting
NCT04042987AbbottNutrition-Focused Quality Improvement Program (QIP) Among Community Dwelling Malnourished Patients

Nutrition-Focused Quality Improvement Program (QIP) Among Community Dwelling Malnourished Patients

Start: Sep 2019Est. completion: Jun 20201,325 patients
N/ACompleted
NCT03679832AbbottA Nutrition-Focused Quality Improvement Program in Hospitalized Malnourished Patients

A Nutrition-Focused Quality Improvement Program in Hospitalized Malnourished Patients

Start: Mar 2019Est. completion: Oct 20191,670 patients
N/ACompleted
NCT03628196AbbottA Nutrition-Focused QIP in Outpatient Clinics

A Nutrition-Focused QIP in Outpatient Clinics

Start: Sep 2018Est. completion: Mar 20201,800 patients
N/ACompleted
NCT03459001AbbottTube Feeding Product

Evaluation of a High Calorie, High Protein Tube Feeding Product in an Adult Population With or at Risk of Malnutrition

Start: Jun 2018Est. completion: Feb 201917 patients
N/ACompleted
NCT03240952AbbottThe Nutritional Health for the Elderly Reference Centre Study (NHERC Study)

The Nutritional Health for the Elderly Reference Centre Study (NHERC Study)

Start: Aug 2017Est. completion: Jul 2018400 patients
N/ACompleted
NCT06200324BaxterParenteral Nutrition

Clinical Outcomes of Ready-to-Use Parenteral Nutrition in Low Birth Weight Newborns in Colombia 2017-2023

Start: Mar 2017Est. completion: Mar 2023284 patients
N/ACompleted
NCT03926715BiocorpNutritional status

Prevalence of Malnutrition in Surgery

Start: Jan 2017Est. completion: Dec 2019700 patients
N/AUnknown
NCT03011944AbbottQuality Improvement Program

Impact of a Nutrition Quality Improvement Program on Outcomes of Malnourished Patients

Start: Dec 2016Est. completion: Mar 20181,546 patients
N/ACompleted
NCT03208725Oregon TherapeuticsChildhood Acute Illness and Nutrition Network

Childhood Acute Illness and Nutrition Network

Start: Nov 2016Est. completion: Oct 20204,335 patients
N/AUnknown
NCT02938247Fresenius KabiHigh caloric, high protein ONS

Tolerance and Compliance of a High Caloric, High Protein Oral Nutritional Supplement - Scheduled Intake

Start: Sep 2016Est. completion: Oct 201620 patients
N/ACompleted
NCT02833740Brixton BiosciencesClick-MUAC prototype & regular MUAC tape

Comparing Performance of Simplified Mid-Upper Arm Circumference Devices ("Click-MUACs") to Detect Acute Malnutrition

Start: Sep 2016Est. completion: Apr 2017345 patients
N/AUnknown
NCT02938234Fresenius KabiHigh caloric, high protein ONS

Tolerance and Compliance of a High Caloric, High Protein Oral Nutritional Supplement - Free Intake

Start: Sep 2016Est. completion: Oct 201620 patients
N/ACompleted
NCT02903641Human BioSciencesPersonalized information

Money or Knowledge? Behavioral Aspects of Malnutrition

Start: Jul 2016Est. completion: Sep 2016506 patients
N/ACompleted
NCT02828150BaxterParenteral Nutrition

Integrative Parenteral Nutrition in Cancer Patients

Start: Jul 2016Est. completion: Dec 2017131 patients
N/ACompleted
NCT02564159BaxterMeasure of quadriceps thickness with ultrasonography and albumin/prealbumin levels

Malnutrition Screening by Muscle Ultrasound in Patients Requiring Mechanical Ventilation in Intensive Care Unit

Start: Oct 2015Est. completion: Aug 2022286 patients
N/ATerminated
NCT02496247Human BioSciencesCanned Herring

Canned Herring for Prevention of Childhood Malnutrition During the Early Rainy Season in Rural Guinea-Bissau

Start: May 2015Est. completion: Aug 20151,200 patients
N/ACompleted
NCT02464111Human BioSciencesTreatment 1: Control

Short Term Response of Breast Milk Micronutrient Concentrations to a Lipid Based Nutrient Supplement in Guatemalan Women

Start: May 2015Est. completion: Aug 201530 patients
N/ACompleted
NCT02505711Heidelberg PharmaHomestead Food Production program

Food and Agricultural Approaches to Reducing Malnutrition

Start: Mar 2015Est. completion: Aug 20212,705 patients
N/ACompleted
NCT02262429AbbottONS QIP

Quality Improvement Program (QIP) to Reduce 30-Day Readmission in Malnourished Hospitalized Patients

Start: Oct 2014Est. completion: Aug 20152,386 patients
N/ATerminated
NCT02052232AbbottExperimental protein powder sachet

Study of Protein Metabolism in Healthy Older Subjects

Start: Mar 2014Est. completion: Apr 201539 patients
N/ACompleted
NCT02066363BaxterParenteral Nutrition

Study of Parenteral Nutrition to Patients With Gastrointestinal Cancer

Start: Mar 2014Est. completion: Aug 201747 patients
N/ATerminated
NCT02089906AbbottHealth and Nutrition Status of Chinese Elderly

Health and Nutrition Status of Chinese Elderly

Start: Mar 2014Est. completion: Jul 20152,834 patients
N/ACompleted
NCT01986153BaxterParenteral Nutrition

Essential Fatty Acid Status & Immune Function in Parenteral Nutrition Patients

Start: Dec 2013Est. completion: Nov 201460 patients
N/ACompleted
NCT01863394Alliance PharmaceuticalsScreening by mothers

Evaluation of Two Community Based Screening Strategies for Severe Acute Malnutrition in Children 6-59 Months in Mirria District, Niger

Start: May 2013Est. completion: Apr 20144,429 patients
N/ACompleted
NCT04085484BaxterParenteral Nutrition

Effects of Two Different Parenteral Nutrition Regimes on Nutrient Intakes, Growth and Plasma Electrolytes in Very Low Birth Weight Infants

Start: Jan 2013Est. completion: Nov 2020134 patients
N/ACompleted
NCT01772927BaxterParenteral Nutrition

Clinical Tolerance of Numeta 13%

Start: Jan 2013Est. completion: Jul 201330 patients
N/AUnknown
NCT03263377UNION therapeuticsThe school feeding intervention

The Impact on School Feeding on Children's Growth and Development

Start: Sep 2011Est. completion: Jun 20133,006 patients
N/ACompleted
NCT01383980Oregon TherapeuticsContinuous Tube Feedings

Trial of Continuous Versus Interrupted Feeding for Intubated Intensive Care Unit Patients

Start: Aug 2011Est. completion: Aug 201736 patients
N/ACompleted
NCT01303016Human BioSciencesChispuditos

Improving Nutrition and Health Outcomes in Intibuca, Honduras

Start: May 2010Est. completion: Dec 2011639 patients
N/AUnknown
NCT00987883UNION therapeuticsThe Impact of Perioperational Malnutrition on the Cost on Gastroenterological Cancer Patients

The Impact of Perioperational Malnutrition on the Cost on Gastroenterological Cancer Patients

Start: Apr 2009Est. completion: Dec 2009200 patients
N/AUnknown
NCT00289380UNION therapeuticsNutrition Support on Outcomes and Cost-effectiveness for Patients at Risk

Nutrition Support on Outcomes and Cost-effectiveness for Patients at Risk

Start: Jan 2005Est. completion: Jan 20402,000 patients
N/ARecruiting

Phase Legend

Preclinical— Lab & animal studies
Phase 1— Safety & dosing
Phase 2— Efficacy testing
Phase 3— Large-scale trials
On Market— Approved & available

Key Insights

3 late-stage (Phase 3) programs, potential near-term approvals
3 actively recruiting trials targeting 48,147 patients
20 companies competing in this space

The information on this page is for informational purposes only and should not be used as a substitute for professional medical advice. Drug information is sourced from FDA, DailyMed, and other government databases. Adverse event data from FAERS does not establish causation. Always consult a healthcare professional for medical decisions.