Lysosomal Storage Diseases

1
Pipeline Programs
2
Companies
2
Clinical Trials
0
Approved Products

Pipeline by Development Stage

Preclinical
Phase 1
Phase 1/2
Phase 2
Phase 2/3
Phase 3
On Market
0
0
0
0
0
1
0
Early DiscoveryClinical DevelopmentMarket

Competitive Landscape

2 companies ranked by most advanced pipeline stage

Orchard Therapeutics
1 program
1
OTL-200Phase 31 trial
Active Trials
NCT04283227Active Not RecruitingEst. Mar 2031
C
CENTOGENEGermany - Rostock
1 program
Lyso-Gb1 as a Long-term Prognostic Biomarker in Gaucher DiseaseN/A1 trial
Active Trials
NCT02416661Completed299Est. Jan 2021

Trial Timeline

Clinical trial activity over time

2021
2022
2023
2024
2025
2026
2027
2028
2029
2030
2031
Orchard TherapeuticsOTL-200
CENTOGENELyso-Gb1 as a Long-term Prognostic Biomarker in Gaucher Disease

Clinical Trials (2)

Total enrollment: 299 patients across 2 trials

OTL-200 in Patients With Late Juvenile Metachromatic Leukodystrophy (MLD)

Start: Jan 2022Est. completion: Mar 2031
Phase 3Active Not Recruiting
NCT02416661CENTOGENELyso-Gb1 as a Long-term Prognostic Biomarker in Gaucher Disease

Lyso-Gb1 as a Long-term Prognostic Biomarker in Gaucher Disease

Start: Aug 2018Est. completion: Jan 2021299 patients
N/ACompleted

Phase Legend

PreclinicalLab & animal studies
Phase 1Safety & dosing
Phase 2Efficacy testing
Phase 3Large-scale trials
On MarketApproved & available

Key Insights

1 late-stage (Phase 3) programs — potential near-term approvals
2 companies competing in this space