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Lyme Borreliosis

5
Pipeline Programs
2
Companies
4
Clinical Trials
0
Approved Products

Pipeline by Development Stage

Preclinical
Phase 1
Phase 1/2
Phase 2
Phase 2/3
Phase 3
On Market
0
0
0
4
0
1
0
Early DiscoveryClinical DevelopmentMarket

Competitive Landscape

2 companies ranked by most advanced pipeline stage

Pfizer
PfizerNEW YORK, NY
3 programs
2
1
VLA15Phase 31 trial
VLA15Phase 21 trial
VLA15Phase 21 trial
Active Trials
NCT03970733Completed246Est. Mar 2022
NCT03769194Completed572Est. Oct 2020
NCT07226882Active Not Recruiting207Est. Jan 2028
Valneva
ValnevaAustria - Vienna
2 programs
2
VLA15Phase 21 trial
VLA15Phase 2
Active Trials
NCT04801420Completed625Est. Jul 2025

Trial Timeline

Clinical trial activity over time

2021
2022
2023
2024
2025
2026
2027
2028
PfizerVLA15
ValnevaVLA15
PfizerVLA15
PfizerVLA15

Clinical Trials (4)

Total enrollment: 1,650 patients across 4 trials

NCT07226882PfizerVLA15

A Study to Learn About Different Dosing Schedules of a Lyme Disease Vaccine in Healthy Adults

Start: Nov 2025Est. completion: Jan 2028207 patients
Phase 3Active Not Recruiting
NCT04801420ValnevaVLA15

Phase 2 Study Of VLA15, A Vaccine Candidate Against Lyme Borreliosis, In A Healthy Pediatric And Adult Study Population

Start: Mar 2021Est. completion: Jul 2025625 patients
Phase 2Completed
NCT03970733PfizerVLA15

Alternative Schedule Study For VLA15, a Vaccine Candidate Against Lyme Borreliosis

Start: Jul 2019Est. completion: Mar 2022246 patients
Phase 2Completed
NCT03769194PfizerVLA15

Immunogenicity and Safety Study of a Vaccine Against Lyme Borreliosis, in Healthy Adults Aged 18 to 65 Years. Randomized, Controlled, Observer-blind Phase 2 Study.

Start: Dec 2018Est. completion: Oct 2020572 patients
Phase 2Completed

Phase Legend

Preclinical— Lab & animal studies
Phase 1— Safety & dosing
Phase 2— Efficacy testing
Phase 3— Large-scale trials
On Market— Approved & available

Key Insights

1 late-stage (Phase 3) programs, potential near-term approvals
2 companies competing in this space

The information on this page is for informational purposes only and should not be used as a substitute for professional medical advice. Drug information is sourced from FDA, DailyMed, and other government databases. Adverse event data from FAERS does not establish causation. Always consult a healthcare professional for medical decisions.