Lung Transplant

1
Pipeline Programs
3
Companies
13
Clinical Trials
1 recruiting
0
Approved Products

Pipeline by Development Stage

Preclinical
Phase 1
Phase 1/2
Phase 2
Phase 2/3
Phase 3
On Market
0
0
0
0
0
1
0
Early DiscoveryClinical DevelopmentMarket

Competitive Landscape

3 companies ranked by most advanced pipeline stage

Sanofi
SanofiPARIS, France
1 program
1
thymoglobulinPhase 35 trials
Active Trials
NCT03099122Completed115Est. Nov 2019
NCT02137876Withdrawn0Est. Mar 2018
NCT01239563Unknown40Est. May 2016
+2 more trials
XVIVO
XVIVOSweden - Mölndal
2 programs
XPS™ with Steen Solution™N/A1 trial
XVIVO Perfusion SystemN/A1 trial
Active Trials
NCT01365429UnknownEst. Dec 2020
NCT05101460RecruitingEst. Apr 2029
Allergy Therapeutics
Allergy TherapeuticsUK - West Sussex
1 program
Blood DrawN/A1 trial
Active Trials
NCT02631720CompletedEst. Nov 2019

Trial Timeline

Clinical trial activity over time

2021
2022
2023
2024
2025
2026
2027
2028
2029
Sanofithymoglobulin
Sanofithymoglobulin
Sanofithymoglobulin
Sanofithymoglobulin
Sanofithymoglobulin
Sanofithymoglobulin
Sanofithymoglobulin
XVIVOXVIVO Perfusion System
Allergy TherapeuticsBlood Draw
Sanofithymoglobulin
XVIVOXPS™ with Steen Solution™
Sanofithymoglobulin
Sanofithymoglobulin

Clinical Trials (13)

Total enrollment: 293 patients across 13 trials

NCT03099122Sanofithymoglobulin

A Study of Thymoglobuline® Induction Therapy in Adult Recipients of Donated After Cardiac Death Kidney Transplant

Start: Aug 2017Est. completion: Nov 2019115 patients
Phase 4Completed
NCT00706680Sanofithymoglobulin

Thymoglobulin in Calcineurin Inhibitor and Steroid Minimization Protocol

Start: Feb 2008Est. completion: Jun 200930 patients
Phase 4Unknown
NCT01239563Sanofithymoglobulin

Thymoglobulin Induction in Kidney Transplant Recipients

Start: Jan 2011Est. completion: May 201640 patients
Phase 3Unknown
NCT01157949Sanofithymoglobulin

A Study to Compare the Effectiveness of a Drug That Suppresses the Immune System Called Thymoglobulin® in Preventing the Development of a Disease That Affects the Majority of Heart Transplant Recipients Called Cardiac Allograft Vasculopathy (CAV)

Start: Nov 2010Est. completion: Jan 20180
Phase 3Withdrawn
NCT00592306Sanofithymoglobulin

Intraoperative Versus Postoperative Thymoglobulin in Lung Transplantation

Start: Jan 2006Est. completion: Sep 20100
Phase 3Withdrawn
NCT00709592Sanofithymoglobulin

Reduced Intensity Total Body Irradiation + Thymoglobulin Followed by Allogeneic PBSCT

Start: Jul 2008Est. completion: Jun 201742 patients
Phase 2Completed
NCT00545519Sanofithymoglobulin

A Phase I Study Of Thymoglobulin In Patients With Relapsed Or Refractory Multiple Myeloma

Start: Oct 2006Est. completion: Mar 20086 patients
Phase 1Completed
NCT05101460XVIVOXVIVO Perfusion System

An All Comers Registry For Normothermic Ex Vivo Lung Perfusion (EVLP) as Assessment of Donor Lungs for Transplant

Start: Oct 2019Est. completion: Apr 2029
N/ARecruiting

CLAD Phenotype Specific Risk Factors and Mechanisms

Start: Dec 2015Est. completion: Nov 2019
N/ACompleted
NCT02137876Sanofithymoglobulin

Effects of Thymoglobulin on Human B Cells

Start: Apr 2014Est. completion: Mar 20180
N/AWithdrawn
NCT01365429XVIVOXPS™ with Steen Solution™

Novel Lung Trial: Normothermic Ex Vivo Lung Perfusion (Evlp) As An Assessment Of Extended/Marginal Donor Lungs

Start: May 2011Est. completion: Dec 2020
N/AUnknown
NCT00842699Sanofithymoglobulin

Characterization of Immunological Profile of Renal Transplant Patients Undergoing Induction Treatment With Thymoglobulin vs. IL-2 Receptor Antagonist Basiliximab

Start: Sep 2008Est. completion: Mar 201140 patients
N/ACompleted
NCT00476229Sanofithymoglobulin

Thymoglobulin and Total Lymphoid Irradiation for Hematologic Malignancies

Start: Jun 2006Est. completion: May 200920 patients
N/ACompleted

Phase Legend

PreclinicalLab & animal studies
Phase 1Safety & dosing
Phase 2Efficacy testing
Phase 3Large-scale trials
On MarketApproved & available

Key Insights

1 late-stage (Phase 3) programs — potential near-term approvals
1 actively recruiting trials targeting 293 patients
3 companies competing in this space