Lumbar Disc Herniation

2
Pipeline Programs
1
Companies
7
Clinical Trials
0
Approved Products

Pipeline by Development Stage

Preclinical
Phase 1
Phase 1/2
Phase 2
Phase 2/3
Phase 3
On Market
0
0
0
0
0
0
2
Early DiscoveryClinical DevelopmentMarket

Competitive Landscape

1 companies ranked by most advanced pipeline stage

Intrinsic Therapeutics
7 programs
2
6mm annular closure devicePhase 41 trial
BarricaidPhase 41 trial
Annular closureN/A1 trial
Annular closure deviceN/A1 trial
BarricaidN/A1 trial
+2 more programs
Active Trials
NCT05467072Unknown250Est. Oct 2025
NCT03986580Unknown55Est. Dec 2024
NCT01534065Completed45Est. Mar 2013
+4 more trials

Trial Timeline

Clinical trial activity over time

2021
2022
2023
2024
2025
2026
Intrinsic Therapeutics6mm annular closure device
Intrinsic TherapeuticsBarricaid
Intrinsic TherapeuticsAnnular closure
Intrinsic TherapeuticsIncidence of Large Annular Defects in Primary Lumbar Discectomy Patients
Intrinsic TherapeuticsAnnular closure device
Intrinsic TherapeuticsFollow up per standard of care
Intrinsic TherapeuticsBarricaid

Clinical Trials (7)

Total enrollment: 1,014 patients across 7 trials

NCT03366779Intrinsic Therapeutics6mm annular closure device

A Post Marketing Surveillance Study

Start: Jan 2018Est. completion: Dec 202420 patients
Phase 4Active Not Recruiting

A Prospective, Randomized, Multicenter Study to Demonstrate the Superiority of the Barricaid to Discectomy for Primary Lumbar Disc Herniation

Start: Dec 2010Est. completion: Jun 2025554 patients
Phase 4Unknown

PMCFU of an Annular Closure System

Start: Sep 2023Est. completion: Oct 2025250 patients
N/AUnknown
NCT03252691Intrinsic TherapeuticsIncidence of Large Annular Defects in Primary Lumbar Discectomy Patients

Incidence of Large Annular Defects in Primary Lumbar Discectomy Patients

Start: Sep 2020Est. completion: May 20210
N/AWithdrawn
NCT03986580Intrinsic TherapeuticsAnnular closure device

Study of Lumbar Discectomy With Annular Closure

Start: May 2020Est. completion: Dec 202455 patients
N/AUnknown
NCT03180749Intrinsic TherapeuticsFollow up per standard of care

Post-Marketing Clinical Follow-Up of a Spine Implant

Start: Mar 2017Est. completion: Sep 202490 patients
N/AUnknown

Barricaid EU Post Market Study for Primary Lumbar Disc Herniation

Start: Apr 2009Est. completion: Mar 201345 patients
N/ACompleted

Phase Legend

PreclinicalLab & animal studies
Phase 1Safety & dosing
Phase 2Efficacy testing
Phase 3Large-scale trials
On MarketApproved & available

Key Insights

1 companies competing in this space