Lumbar Degenerative Disc Disease

0
Pipeline Programs
2
Companies
3
Clinical Trials
0
Approved Products

Pipeline by Development Stage

Preclinical
Phase 1
Phase 1/2
Phase 2
Phase 2/3
Phase 3
On Market
0
0
0
0
0
0
0
Early DiscoveryClinical DevelopmentMarket

Competitive Landscape

2 companies ranked by most advanced pipeline stage

Globus Medical
Globus MedicalAUDUBON, PA
2 programs
Open PLIFN/A1 trial
TRIUMPH® Lumbar Artificial DiscN/A1 trial
Active Trials
NCT01640977CompletedEst. Sep 2014
NCT01198470Completed20Est. Dec 2016
Bioventus
BioventusDURHAM, NC
1 program
Exospine shamN/A1 trial
Active Trials
NCT00744861Terminated328Est. May 2012

Trial Timeline

Clinical trial activity over time

2021
2022
2023
2024
2025
2026
Globus MedicalOpen PLIF
Globus MedicalTRIUMPH® Lumbar Artificial Disc
BioventusExospine sham

Clinical Trials (3)

Total enrollment: 348 patients across 3 trials

NCT01640977Globus MedicalOpen PLIF

A Prospective Non-concurrent Controlled Evaluation of Open and MAS® PLIF

Start: Jun 2012Est. completion: Sep 2014
N/ACompleted
NCT01198470Globus MedicalTRIUMPH® Lumbar Artificial Disc

TRIUMPH Lumbar Artificial Disc IDE: A Pilot Study

Start: Sep 2010Est. completion: Dec 201620 patients
N/ACompleted
NCT00744861BioventusExospine sham

Ultrasound as Adjunct Therapy for Increasing Fusion Success After Lumbar Surgery

Start: Sep 2008Est. completion: May 2012328 patients
N/ATerminated

Phase Legend

Preclinical— Lab & animal studies
Phase 1— Safety & dosing
Phase 2— Efficacy testing
Phase 3— Large-scale trials
On Market— Approved & available

Key Insights

2 companies competing in this space