Long-chain Fatty Acid Oxidation Disorders (LC-FAOD)

3
Pipeline Programs
1
Companies
2
Clinical Trials
1
Approved Products

Pipeline by Development Stage

Preclinical
Phase 1
Phase 1/2
Phase 2
Phase 2/3
Phase 3
On Market
0
0
0
1
0
1
1
Early DiscoveryClinical DevelopmentMarket

On Market (1)

Approved therapies currently available

Ultragenyx Pharmaceutical
DOJOLVIApproved
triheptanoin
Ultragenyx Pharmaceutical
Medium-chain Triglyceride [EPC]oral2020

Competitive Landscape

1 companies ranked by most advanced pipeline stage

Ultragenyx Pharmaceutical
2 programs
1
1
1
TriheptanoinPhase 31 trial
UX007Phase 21 trial
Active Trials
NCT01886378Completed29Est. Aug 2016
NCT05933200Active Not Recruiting69Est. Aug 2027

Trial Timeline

Clinical trial activity over time

2021
2022
2023
2024
2025
2026
2027
Ultragenyx PharmaceuticalTriheptanoin
Ultragenyx PharmaceuticalUX007

Clinical Trials (2)

Total enrollment: 98 patients across 2 trials

A Study to Determine the Effect of Triheptanoin Compared With Even-Chain MCT on MCEs in Pediatric Patients With LC-FAOD

Start: Feb 2023Est. completion: Aug 202769 patients
Phase 3Active Not Recruiting

A Study of UX007 (Triheptanoin) in Participants With Long-Chain Fatty Acid Oxidation Disorders (LC-FAOD)

Start: Feb 2014Est. completion: Aug 201629 patients
Phase 2Completed

Phase Legend

PreclinicalLab & animal studies
Phase 1Safety & dosing
Phase 2Efficacy testing
Phase 3Large-scale trials
On MarketApproved & available

Key Insights

1 late-stage (Phase 3) programs — potential near-term approvals
1 companies competing in this space