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Left Atrial Appendage Exclusion

2
Pipeline Programs
2
Companies
2
Clinical Trials
0
Approved Products

Pipeline by Development Stage

Preclinical
Phase 1
Phase 1/2
Phase 2
Phase 2/3
Phase 3
On Market
0
0
0
1
0
0
1
Early DiscoveryClinical DevelopmentMarket

Competitive Landscape

2 companies ranked by most advanced pipeline stage

AtriCure
AtriCureCA - Pleasanton
2 programs
1
1
AtriClip LAA Exclusion SystemPhase 4
AtriCure LAA Exclusion SystemPhase 21 trial
Active Trials
NCT00779857Completed70Est. Oct 2011
Medtronic
MedtronicNJ - Phillipsburg
1 program
Penditure™ Left Atrial AppendageN/A1 trial
Active Trials
NCT06203054Active Not Recruiting198Est. Feb 2029

Trial Timeline

Clinical trial activity over time

2021
2022
2023
2024
2025
2026
2027
2028
2029
AtriCureAtriCure LAA Exclusion System
MedtronicPenditure™ Left Atrial Appendage

Clinical Trials (2)

Total enrollment: 268 patients across 2 trials

NCT00779857AtriCureAtriCure LAA Exclusion System

AtriCure Exclusion of the LAA in Patients Undergoing Concomitant Cardiac Surgery

Start: Sep 2008Est. completion: Oct 201170 patients
Phase 2Completed
NCT06203054MedtronicPenditure™ Left Atrial Appendage

CLIP-IT Post-Market Study

Start: Feb 2024Est. completion: Feb 2029198 patients
N/AActive Not Recruiting

Phase Legend

PreclinicalLab & animal studies
Phase 1Safety & dosing
Phase 2Efficacy testing
Phase 3Large-scale trials
On MarketApproved & available

Key Insights

2 companies competing in this space

The information on this page is for informational purposes only and should not be used as a substitute for professional medical advice. Drug information is sourced from FDA, DailyMed, and other government databases. Adverse event data from FAERS does not establish causation. Always consult a healthcare professional for medical decisions.