Krabbe Disease

2
Pipeline Programs
2
Companies
4
Clinical Trials
0
Approved Products

Pipeline by Development Stage

Preclinical
Phase 1
Phase 1/2
Phase 2
Phase 2/3
Phase 3
On Market
0
0
2
0
0
0
0
Early DiscoveryClinical DevelopmentMarket

Competitive Landscape

2 companies ranked by most advanced pipeline stage

Forge Biologics
Forge BiologicsOH - Grove City
3 programs
2
FBX-101Phase 1/21 trial
FBX-101Phase 1/21 trial
FBX-101N/A1 trial
Active Trials
NCT06308718Terminated2Est. Apr 2025
NCT04693598Active Not Recruiting6Est. Nov 2026
NCT05739643Active Not Recruiting9Est. Nov 2026
C
CENTOGENEGermany - Rostock
1 program
Biomarker for Krabbe Disease (BioKrabbe)N/A1 trial
Active Trials
NCT01425489Withdrawn0Est. Feb 2021

Trial Timeline

Clinical trial activity over time

2021
2022
2023
2024
2025
2026
Forge BiologicsFBX-101
Forge BiologicsFBX-101
Forge BiologicsFBX-101
CENTOGENEBiomarker for Krabbe Disease (BioKrabbe)

Clinical Trials (4)

Total enrollment: 17 patients across 4 trials

Gene Transfer Clinical Trial for Infantile and Late Infantile Krabbe Disease Treated Previously With HSCT

Start: Feb 2023Est. completion: Nov 20269 patients
Phase 1/2Active Not Recruiting

Gene Transfer Clinical Trial for Krabbe Disease

Start: Nov 2021Est. completion: Nov 20266 patients
Phase 1/2Active Not Recruiting

Long-term Follow-up Study to Evaluate Safety and Efficacy of FBX-101 in Krabbe Patients

Start: Aug 2024Est. completion: Apr 20252 patients
N/ATerminated
NCT01425489CENTOGENEBiomarker for Krabbe Disease (BioKrabbe)

Biomarker for Krabbe Disease (BioKrabbe)

Start: Aug 2018Est. completion: Feb 20210
N/AWithdrawn

Phase Legend

PreclinicalLab & animal studies
Phase 1Safety & dosing
Phase 2Efficacy testing
Phase 3Large-scale trials
On MarketApproved & available

Key Insights

2 companies competing in this space