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Knee Arthroplasty

1
Pipeline Programs
3
Companies
5
Clinical Trials
0
Approved Products

Pipeline by Development Stage

Preclinical
Phase 1
Phase 1/2
Phase 2
Phase 2/3
Phase 3
On Market
0
0
0
0
0
0
1
Early DiscoveryClinical DevelopmentMarket

Competitive Landscape

3 companies ranked by most advanced pipeline stage

Zimmer Biomet
Zimmer BiometFL - Jacksonville
2 programs
1
Computer assistPhase 41 trial
Oxford Partial KneeN/A1 trial
Active Trials
NCT00759616Completed156Est. Jun 2009
NCT00300326Terminated7Est. Jan 2012
Stryker
StrykerCA - San Jose
2 programs
Non-MAKO® Robot Assisted Total Knee ArthroplastyN/A1 trial
Total Knee ArthroplastyN/A1 trial
Active Trials
NCT01705366Terminated316Est. Sep 2018
NCT01705886Completed62Est. Oct 2023
Innovation Pharmaceuticals
1 program
Active tDCS StimulationN/A1 trial
Active Trials
NCT07351578Not Yet Recruiting70Est. Dec 2027

Trial Timeline

Clinical trial activity over time

2021
2022
2023
2024
2025
2026
2027
Zimmer BiometComputer assist
Innovation PharmaceuticalsActive tDCS Stimulation
StrykerTotal Knee Arthroplasty
StrykerNon-MAKO® Robot Assisted Total Knee Arthroplasty
Zimmer BiometOxford Partial Knee

Clinical Trials (5)

Total enrollment: 611 patients across 5 trials

Computer-assisted Total Knee Arthroplasty (TKA) With Zimmer LPS Flex Knee System

Start: Jan 2006Est. completion: Jan 20127 patients
Phase 4Terminated

Knee Arthroplasty Recovery With Transcranial Direct Current Stimulation

Start: May 2026Est. completion: Dec 202770 patients
N/ANot Yet Recruiting
NCT01705886StrykerTotal Knee Arthroplasty

Clinical and Economic Comparison of Robot Assisted Versus Manual Knee Replacement

Start: Oct 2012Est. completion: Oct 202362 patients
N/ACompleted
NCT01705366StrykerNon-MAKO® Robot Assisted Total Knee Arthroplasty

Clinical Outcomes of Knee Replacement

Start: Oct 2012Est. completion: Sep 2018316 patients
N/ATerminated
NCT00759616Zimmer BiometOxford Partial Knee

Outcome Analysis of the Oxford Partial Knee Arthroplasty

Start: Apr 2003Est. completion: Jun 2009156 patients
N/ACompleted

Phase Legend

PreclinicalLab & animal studies
Phase 1Safety & dosing
Phase 2Efficacy testing
Phase 3Large-scale trials
On MarketApproved & available

Key Insights

3 companies competing in this space

The information on this page is for informational purposes only and should not be used as a substitute for professional medical advice. Drug information is sourced from FDA, DailyMed, and other government databases. Adverse event data from FAERS does not establish causation. Always consult a healthcare professional for medical decisions.