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Klinefelter Syndrome

4
Pipeline Programs
3
Companies
6
Clinical Trials
1 recruiting
0
Approved Products

Pipeline by Development Stage

Preclinical
Phase 1
Phase 1/2
Phase 2
Phase 2/3
Phase 3
On Market
0
0
0
0
0
0
4
Early DiscoveryClinical DevelopmentMarket

Competitive Landscape

3 companies ranked by most advanced pipeline stage

Colorado Therapeutics
Colorado TherapeuticsCO - Louisville
5 programs
3
Fenofibrate 145 mgPhase 41 trial
Testosterone Cypionate 200 Milligram/Milliliter Injectable SolutionPhase 41 trial
testosterone cypionate 200mg/mlPhase 41 trial
Assessments of Development and GrowthN/A1 trial
Testosterone gel 1%N/A1 trial
Active Trials
NCT03396562Recruiting300Est. Mar 2028
NCT01585831Completed48Est. Oct 2017
NCT05498090Unknown44Est. Aug 2025
+2 more trials
Human BioSciences
Human BioSciencesWV - Martinsburg
2 programs
1
Testosterone Cypionate 200 Milligram/Milliliter Injectable SolutionPhase 4
Adaptation Among Adolescents and Adults With Klinefelter SyndromeN/A
Genome & Company
Genome & CompanyKorea - Suwon
1 program
Adaptation Among Adolescents and Adults With Klinefelter SyndromeN/A1 trial
Active Trials
NCT00896272Completed302Est. Jan 2015

Trial Timeline

Clinical trial activity over time

2021
2022
2023
2024
2025
2026
2027
2028
Colorado TherapeuticsFenofibrate 145 mg
Colorado TherapeuticsTestosterone Cypionate 200 Milligram/Milliliter Injectable Solution
Colorado Therapeuticstestosterone cypionate 200mg/ml
Colorado TherapeuticsAssessments of Development and Growth
Colorado TherapeuticsTestosterone gel 1%
Genome & CompanyAdaptation Among Adolescents and Adults With Klinefelter Syndrome

Clinical Trials (6)

Total enrollment: 786 patients across 6 trials

NCT05498090Colorado TherapeuticsFenofibrate 145 mg

Interrogating Fatty Acid Metabolism Impairment and Clinical Correlates in Males with Klinefelter Syndrome

Start: Nov 2022Est. completion: Aug 202544 patients
Phase 4Unknown
NCT03325647Colorado TherapeuticsTestosterone Cypionate 200 Milligram/Milliliter Injectable Solution

TESTO: Testosterone Effects on Short-Term Outcomes in Infants With XXY

Start: Nov 2017Est. completion: May 202172 patients
Phase 4Completed
NCT02408445Colorado Therapeuticstestosterone cypionate 200mg/ml

Body Composition in Infants With Klinefelter Syndrome and Effects of Testosterone Treatment

Start: May 2015Est. completion: Jan 202020 patients
Phase 4Completed
NCT03396562Colorado TherapeuticsAssessments of Development and Growth

The eXtroardinarY Babies Study: Natural History of Health and Neurodevelopment in Infants and Young Children With Sex Chromosome Trisomy

Start: Sep 2017Est. completion: Mar 2028300 patients
N/ARecruiting
NCT01585831Colorado TherapeuticsTestosterone gel 1%

Study of Psychological and Motor Effects of Testosterone in Adolescents With XXY/Klinefelter Syndrome

Start: Mar 2012Est. completion: Oct 201748 patients
N/ACompleted
NCT00896272Genome & CompanyAdaptation Among Adolescents and Adults With Klinefelter Syndrome

Adaptation Among Adolescents and Adults With Klinefelter Syndrome

Start: May 2009Est. completion: Jan 2015302 patients
N/ACompleted

Phase Legend

Preclinical— Lab & animal studies
Phase 1— Safety & dosing
Phase 2— Efficacy testing
Phase 3— Large-scale trials
On Market— Approved & available

Key Insights

1 actively recruiting trials targeting 786 patients
3 companies competing in this space

The information on this page is for informational purposes only and should not be used as a substitute for professional medical advice. Drug information is sourced from FDA, DailyMed, and other government databases. Adverse event data from FAERS does not establish causation. Always consult a healthcare professional for medical decisions.