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Intraventricular Hemorrhage

1
Pipeline Programs
9
Companies
10
Clinical Trials
2 recruiting
0
Approved Products

Pipeline by Development Stage

Preclinical
Phase 1
Phase 1/2
Phase 2
Phase 2/3
Phase 3
On Market
0
0
1
0
0
0
0
Early DiscoveryClinical DevelopmentMarket

Competitive Landscape

9 companies ranked by most advanced pipeline stage

Human BioSciences
Human BioSciencesWV - Martinsburg
3 programs
1
IndomethacinPhase 1/21 trial
Umbilical Cord MilkingN/A
V-DCCN/A
Active Trials
NCT02221219Completed256Est. Aug 2021
IRRAS
IRRASSweden - Stockholm
2 programs
IRRAflowN/A1 trial
IRRAflow with Active Fluid Exchange SystemN/A1 trial
Active Trials
NCT05204849Unknown58Est. Feb 2025
NCT05649904Recruiting240Est. Jan 2026
Sharp Therapeutics
Sharp TherapeuticsPA - Pittsburgh
2 programs
Umbilical Cord MilkingN/A1 trial
V-DCCN/A1 trial
Active Trials
NCT01866982Completed197Est. Jan 2018
NCT02231411Completed150Est. Aug 2016
Integra LifeSciences
Integra LifeSciencesAustralia - Clayton
1 program
CerebroFlo™ EVD CatheterN/A1 trial
Active Trials
NCT05113381Completed105Est. Jul 2025
Heidelberg Pharma
Heidelberg PharmaGermany - Ladenburg
1 program
External drainage of intraventricular hemorrhageN/A1 trial
Active Trials
NCT06510842Recruiting354Est. Jul 2029
Colorado Therapeutics
Colorado TherapeuticsCO - Louisville
1 program
Standard 30-60 Seconds Cord ClampingN/A1 trial
Active Trials
NCT02742454Unknown570Est. Dec 2023
Oregon Therapeutics
Oregon TherapeuticsFrance - Paris
1 program
Standard 30-60 Seconds Cord ClampingN/A
Genomics
GenomicsUK - Oxford
1 program
collection of CSF and bloodN/A1 trial
Active Trials
NCT02386228Terminated1Est. Dec 2016
Genentech
GenentechCA - Oceanside
1 program
AlteplasePHASE_31 trial
Active Trials
NCT00784134Completed500Est. Jan 2016

Trial Timeline

Clinical trial activity over time

2021
2022
2023
2024
2025
2026
2027
2028
2029
GenentechAlteplase
Human BioSciencesIndomethacin
Heidelberg PharmaExternal drainage of intraventricular hemorrhage
IRRASIRRAflow with Active Fluid Exchange System
IRRASIRRAflow
Integra LifeSciencesCerebroFlo™ EVD Catheter
Colorado TherapeuticsStandard 30-60 Seconds Cord Clamping
Genomicscollection of CSF and blood
Sharp TherapeuticsV-DCC
Sharp TherapeuticsUmbilical Cord Milking

Clinical Trials (10)

Total enrollment: 2,431 patients across 10 trials

NCT00784134GenentechAlteplase

Clot Lysis: Evaluating Accelerated Resolution of Intraventricular Hemorrhage Phase III

Start: Jul 2009Est. completion: Jan 2016500 patients
Phase 3Completed
NCT02221219Human BioSciencesIndomethacin

Effects of Delayed Cord Clamp and/or Indomethacin on Preterm Infant Brain Injury

Start: Aug 2014Est. completion: Aug 2021256 patients
Phase 1/2Completed
NCT06510842Heidelberg PharmaExternal drainage of intraventricular hemorrhage

Lumbar Drainage of Intraventricular Hemorrhage

Start: Jan 2025Est. completion: Jul 2029354 patients
N/ARecruiting
NCT05649904IRRASIRRAflow with Active Fluid Exchange System

AFFECT Study for Patients With Intraventricular Hemorrhage, Subarachnoid Hemorrhage, Subdural Hematoma, and Ventriculitis

Start: Feb 2023Est. completion: Jan 2026240 patients
N/ARecruiting
NCT05204849IRRASIRRAflow

ACTIVE Study - Use of ACTIVE Fluid Exchange to Treat Intraventricular Hemorrhage

Start: Jan 2022Est. completion: Feb 202558 patients
N/AUnknown
NCT05113381Integra LifeSciencesCerebroFlo™ EVD Catheter

The Purpose of This Study is to Determine Whether CerebroFlo™ EVD Catheter is Effective During the Treatment of Intraventricular Hemorrhage (IVH)

Start: Sep 2021Est. completion: Jul 2025105 patients
N/ACompleted
NCT02742454Colorado TherapeuticsStandard 30-60 Seconds Cord Clamping

VentFirst: A Multicenter RCT of Assisted Ventilation During Delayed Cord Clamping for Extremely Preterm Infants

Start: Jun 2016Est. completion: Dec 2023570 patients
N/AUnknown
NCT02386228Genomicscollection of CSF and blood

Micro Ribonucleic Acid (miRNA) Markers of Hydrocephalus in Intraventricular Hemorrhage (IVH)

Start: Mar 2015Est. completion: Dec 20161 patients
N/ATerminated
NCT02231411Sharp TherapeuticsV-DCC

Neonatal Resuscitation With Intact Cord

Start: Aug 2014Est. completion: Aug 2016150 patients
N/ACompleted
NCT01866982Sharp TherapeuticsUmbilical Cord Milking

The PREMOD Trial: A Randomized Controlled Trial of Umbilical Cord Milking vs. Delayed Cord Clamping in Premature Infants

Start: Jul 2013Est. completion: Jan 2018197 patients
N/ACompleted

Phase Legend

Preclinical— Lab & animal studies
Phase 1— Safety & dosing
Phase 2— Efficacy testing
Phase 3— Large-scale trials
On Market— Approved & available

Key Insights

2 actively recruiting trials targeting 2,431 patients
9 companies competing in this space

The information on this page is for informational purposes only and should not be used as a substitute for professional medical advice. Drug information is sourced from FDA, DailyMed, and other government databases. Adverse event data from FAERS does not establish causation. Always consult a healthcare professional for medical decisions.