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Infective Endocarditis

0
Pipeline Programs
6
Companies
5
Clinical Trials
0
Approved Products

Pipeline by Development Stage

Preclinical
Phase 1
Phase 1/2
Phase 2
Phase 2/3
Phase 3
On Market
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0
0
0
0
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Early DiscoveryClinical DevelopmentMarket

Competitive Landscape

6 companies ranked by most advanced pipeline stage

CytoSorbents
CytoSorbentsPRINCETON, NJ
2 programs
CytoSorbN/A1 trial
hemoadsorber for removal of cytokinesN/A1 trial
Active Trials
NCT03945708Completed20Est. Dec 2020
NCT03266302Completed288Est. Dec 2020
AngioDynamics
AngioDynamicsChina - Hong Kong
1 program
AngioVac SystemN/A1 trial
Active Trials
NCT07282002Not Yet Recruiting30Est. Mar 2027
Biocorp
BiocorpFrance - Issoire
1 program
Cryopreserved Aortic HomograftN/A1 trial
Active Trials
NCT05253469Enrolling By Invitation760Est. Dec 2026
NoRD Bio
NoRD BioMA - Cambridge
1 program
Cryopreserved Aortic HomograftN/A
Thermo Fisher Scientific
1 program
hemoadsorber for removal of cytokinesN/A
Merck & Co.
Merck & Co.RAHWAY, NJ
1 program
daptomycinPHASE_41 trial
Active Trials
NCT00638157Terminated24Est. Nov 2011

Trial Timeline

Clinical trial activity over time

2021
2022
2023
2024
2025
2026
2027
Merck & Co.daptomycin
AngioDynamicsAngioVac System
CytoSorbentsCytoSorb
CytoSorbentshemoadsorber for removal of cytokines
BiocorpCryopreserved Aortic Homograft

Clinical Trials (5)

Total enrollment: 1,122 patients across 5 trials

NCT00638157Merck & Co.daptomycin

Phase 4 Efficacy and Safety Study of Cubicin® With and Without Combination Therapy in S. Aureus Infective Endocarditis (SAIE)

Start: Feb 2009Est. completion: Nov 201124 patients
Phase 4Terminated
NCT07282002AngioDynamicsAngioVac System

Percutaneous AngioVac Vegetation Extraction (PAVE) to Remove Right Heart Vegetations in Patients With Infective Endocarditis

Start: Apr 2026Est. completion: Mar 202730 patients
N/ANot Yet Recruiting
NCT03945708CytoSorbentsCytoSorb

Does Whole Blood Adsorber During CPB Reduce Vasoactive Drugs Postoperatively in Endocarditis Patients Undergoing Valve Surgery?

Start: May 2019Est. completion: Dec 202020 patients
N/ACompleted
NCT03266302CytoSorbentshemoadsorber for removal of cytokines

Hemoadsorption for Prevention of Vasodilatory Shock in Cardiac Surgery Patients With Infective Endocarditis

Start: Jan 2018Est. completion: Dec 2020288 patients
N/ACompleted
NCT05253469BiocorpCryopreserved Aortic Homograft

Infective Endocarditis Surgery Using Conventional Prosthetic Valves Versus Cryopreserved Aortic Homograft

Start: Jan 2005Est. completion: Dec 2026760 patients
N/AEnrolling By Invitation

Phase Legend

Preclinical— Lab & animal studies
Phase 1— Safety & dosing
Phase 2— Efficacy testing
Phase 3— Large-scale trials
On Market— Approved & available

Key Insights

6 companies competing in this space

The information on this page is for informational purposes only and should not be used as a substitute for professional medical advice. Drug information is sourced from FDA, DailyMed, and other government databases. Adverse event data from FAERS does not establish causation. Always consult a healthcare professional for medical decisions.