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Infectious Disease

4
Pipeline Programs
7
Companies
10
Clinical Trials
1 recruiting
0
Approved Products

Pipeline by Development Stage

Preclinical
Phase 1
Phase 1/2
Phase 2
Phase 2/3
Phase 3
On Market
0
2
1
0
0
0
1
Early DiscoveryClinical DevelopmentMarket

Drug Modality Breakdown

Small Molecule
150%
Vaccine
150%
+ 7 programs with unclassified modality

Competitive Landscape

7 companies ranked by most advanced pipeline stage

Relief Therapeutics
Relief TherapeuticsSwitzerland - Geneva
1 program
1
7-valent pneumococcal conjugated vaccinePhase 4Vaccine1 trial
Active Trials
NCT02040402Completed100Est. Dec 2010
Gangagen
GangagenIndia - Bangalore
1 program
1
P128-0.1 mgPhase 1/21 trial
Active Trials
NCT01746654Completed74Est. Dec 2015
MSD
MSDIreland - Ballydine
2 programs
1
MK-7655Phase 1
Pharmacist-led InterventionN/A
Sharp Therapeutics
Sharp TherapeuticsPA - Pittsburgh
2 programs
1
MK-7655Phase 1
Pharmacist-led InterventionN/A
Labcorp
LabcorpBURLINGTON, NC
1 program
District health information packageN/A1 trial
Active Trials
NCT01003587Unknown594Est. Jul 2016
Merck & Co.
Merck & Co.RAHWAY, NJ
1 program
MK-7655PHASE_15 trials
Active Trials
NCT03969901Completed115Est. May 2024
NCT03583333Completed274Est. Jul 2022
NCT03230916Completed47Est. Aug 2020
+2 more trials
FUJIFILM Pharma
FUJIFILM PharmaMA - Cambridge
1 program
favipiravirPHASE_1Small Molecule1 trial
Active Trials
NCT06024421Recruiting39Est. Nov 2027

Trial Timeline

Clinical trial activity over time

2021
2022
2023
2024
2025
2026
2027
Relief Therapeutics7-valent pneumococcal conjugated vaccine
Merck & Co.MK-7655
Merck & Co.MK-7655
Merck & Co.MK-7655
Merck & Co.MK-7655
GangagenP128-0.1 mg
FUJIFILM Pharmafavipiravir
Merck & Co.MK-7655
Merck & Co.MK-7655
LabcorpDistrict health information package

Clinical Trials (10)

Total enrollment: 1,912 patients across 10 trials

NCT02040402Relief Therapeutics7-valent pneumococcal conjugated vaccine

Immunogenicity of 3+1 Versus 2+1 Schedule for PCV7

Start: Feb 2009Est. completion: Dec 2010100 patients
Phase 4Completed

Imipenem/Cilastatin/Relebactam (MK-7655A) Versus Piperacillin/Tazobactam in Participants With Hospital-Acquired or Ventilator-Associated Bacterial Pneumonia (MK-7655A-016)

Start: Sep 2018Est. completion: Jul 2022274 patients
Phase 3Completed

Efficacy and Safety of Imipenem+Cilastatin/Relebactam (MK-7655A) in Japanese Participants With Complicated Intra-abdominal Infection or Complicated Urinary Tract Infection (MK-7655A-017)

Start: Oct 2017Est. completion: Sep 201883 patients
Phase 3Completed

Imipenem/Relebactam/Cilastatin Versus Piperacillin/Tazobactam for Treatment of Participants With Bacterial Pneumonia (MK-7655A-014)

Start: Nov 2015Est. completion: Apr 2019537 patients
Phase 3Completed

Safety, Tolerability, Efficacy and Pharmacokinetics of Imipenem/Cilastatin/Relebactam (MK-7655A) in Pediatric Participants With Gram-negative Bacterial Infection (MK-7655A-021)

Start: Oct 2019Est. completion: May 2024115 patients
Phase 2/3Completed

Safety & Efficacy of an Antibacterial Protein Molecule Applied Topically to the Nostrils of Volunteers and Patients

Start: Dec 2012Est. completion: Dec 201574 patients
Phase 1/2Completed

Evaluation of Tolerance and Pharmacokinetic Profile of High Doses of Favipiravir in Healthy Volunteers

Start: May 2024Est. completion: Nov 202739 patients
Phase 1Recruiting

A Pharmacokinetics Study of MK-7655A in Pediatric Participants With Gram-negative Infections (MK-7655A-020)

Start: Nov 2017Est. completion: Aug 202047 patients
Phase 1Completed

A Single-Dose Study to Investigate the Pharmacokinetics of MK-7655 in Participants With Impaired Renal Function (MK-7655-005)

Start: Jan 2011Est. completion: Mar 201249 patients
Phase 1Completed
NCT01003587LabcorpDistrict health information package

Promoting Evidence-Based Decision-Making in India: District Evaluation Study on Health

Start: Jul 2009Est. completion: Jul 2016594 patients
N/AUnknown

Phase Legend

PreclinicalLab & animal studies
Phase 1Safety & dosing
Phase 2Efficacy testing
Phase 3Large-scale trials
On MarketApproved & available

Key Insights

1 actively recruiting trials targeting 1,912 patients
7 companies competing in this space

The information on this page is for informational purposes only and should not be used as a substitute for professional medical advice. Drug information is sourced from FDA, DailyMed, and other government databases. Adverse event data from FAERS does not establish causation. Always consult a healthcare professional for medical decisions.