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Infections, Bacterial

31
Pipeline Programs
5
Companies
19
Clinical Trials
0
Approved Products

Pipeline by Development Stage

Preclinical
Phase 1
Phase 1/2
Phase 2
Phase 2/3
Phase 3
On Market
0
24
0
4
0
0
3
Early DiscoveryClinical DevelopmentMarket

Competitive Landscape

5 companies ranked by most advanced pipeline stage

ViiV Healthcare
ViiV HealthcareNC - Durham
30 programs
24
4
1
AVAPhase 4
Augmentin ESPhase 2
GSK2140944 LyophilePhase 2
GepotidacinPhase 2
retapamulinPhase 2
+25 more programs
Emergent BioSolutions
3 programs
2
AVAPhase 4
Sample CollectionPhase 41 trial
Collection of samplesN/A
Active Trials
NCT02177721Not Yet Recruiting100Est. Dec 2035
GSK
GSKLONDON, United Kingdom
17 programs
Antibiotic prescription during the study period between January 1, 2004 and December 31, 2009N/A1 trial
100 mg GSK investigational drugPHASE_11 trial
Cefixime test capsulePHASE_11 trial
GR37547 tabletPHASE_11 trial
GSK1322322PHASE_11 trial
+12 more programs
Active Trials
NCT01587768Completed1Est. Jul 2014
NCT00828867Completed41Est. Dec 2009
NCT03329547Withdrawn0Est. Feb 2018
+14 more trials
Human BioSciences
Human BioSciencesWV - Martinsburg
1 program
Collection of samplesN/A1 trial
Active Trials
NCT07478471Not Yet Recruiting10Est. Dec 2030
Parexel
ParexelMA - Boston
1 program
GR37547 tabletPHASE_1

Trial Timeline

Clinical trial activity over time

2021
2022
2023
2024
2025
2026
2027
2028
2029
2030
2031
Emergent BioSolutionsSample Collection
GSKAVA
GSKAugmentin ES
GSKGepotidacin
GSKGSK2140944 Lyophile
GSKGepotidacin
GSKTest formulation A
GSKCefixime test capsule
GSKGR37547 tablet
GSKGepotidacin RC Tablet
GSKGepotidacin
GSKGSK2140944
GSKGSK1322322 1000 mg containing radioactive 14C-GSK1322322
GSKGSK1322322
GSKGSK1322322

Showing 15 of 19 trials with date data

Clinical Trials (19)

Total enrollment: 1,127 patients across 19 trials

Clinical Benefit and Safety of Raxibacumab in Patients With Symptomatic Inhalational Anthrax in a Mass Exposure Scenario

Start: Jan 2027Est. completion: Dec 2035100 patients
Phase 4Not Yet Recruiting

Effect of Raxibacumab on Immunogenicity of Anthrax Vaccine Adsorbed

Start: Feb 2015Est. completion: Jun 2017573 patients
Phase 4Completed
NCT05340257GSKAugmentin ES

A Pharmacokinetics and Safety Study of Augmentin ES-600 in Children With CAP and ABRS

Start: Oct 2023Est. completion: Jul 20240
Phase 2Withdrawn
NCT03568942GSKGepotidacin

Pharmacokinetic Study of Oral Gepotidacin (GSK2140944) in Subjects With Uncomplicated Urinary Tract Infection (Acute Cystitis)

Start: Jul 2018Est. completion: Jan 201922 patients
Phase 2Completed
NCT02045797GSKGSK2140944 Lyophile

Dose-Ranging Study of GSK2140944 in the Treatment of Subjects With Suspected or Confirmed Gram-Positive Acute Bacterial Skin and Skin Structure Infections

Start: Mar 2014Est. completion: Jun 2015126 patients
Phase 2Completed
NCT03562117GSKGepotidacin

Pharmacokinetics (PK) Study of Gepotidacin (GSK2140944) in Adult Subjects With Varying Degrees of Hepatic Impairment and in Matched Control Subjects With Normal Hepatic Function

Start: Jun 2018Est. completion: Dec 201825 patients
Phase 1Completed
NCT03408392GSKTest formulation A

Bioequivalence Study Between SKF101804 Cefixime 200 Milligram (mg)/5 Milliliter (mL) Suspension Versus Cefixime 200 mg/5 mL Suspension Reference Product in Healthy Adult Subjects Under Fasting Conditions

Start: Feb 2018Est. completion: Mar 201828 patients
Phase 1Completed
NCT03329547GSKCefixime test capsule

A Bioequivalence Study of SKF101804 Cefixime Versus Cefixime Reference Formulation in Healthy Adults Under Fasting Conditions

Start: Jan 2018Est. completion: Feb 20180
Phase 1Withdrawn
NCT03150082GSKGR37547 tablet

Bioequivalence Study Between GR37547 500 Milligrams (mg) Tablet Versus Ciprofloxacin 500 mg Tablet Reference Product in Healthy Adult Subjects

Start: Aug 2017Est. completion: Aug 201726 patients
Phase 1Completed
NCT02853435GSKGepotidacin RC Tablet

To Assess Bioavailability, Food Effect and Pharmacokinetics of Gepotidacin Tablets: A Phase I, Single-Dose, 2 Part Study in Healthy Subjects.

Start: Aug 2016Est. completion: Oct 201748 patients
Phase 1Completed
NCT02729038GSKGepotidacin

Pharmacokinetic Study of Gepotidacin in Subjects With Varying Degrees of Renal Impairment and in Subjects With Normal Renal Function

Start: Jun 2016Est. completion: Jun 201732 patients
Phase 1Completed
NCT01934205GSKGSK2140944

To Evaluate Plasma and Pulmonary Pharmacokinetics of GSK2140944

Start: Sep 2013Est. completion: Dec 201322 patients
Phase 1Completed
NCT01663389GSKGSK1322322 1000 mg containing radioactive 14C-GSK1322322

A Study to Investigate the Recovery, Excretion, and Pharmacokinetics of 14C -GSK1322322 After an Intravenous and an Oral Dose

Start: Aug 2012Est. completion: Oct 20125 patients
Phase 1Completed
NCT01648179GSKGSK1322322

A Study to Assess the Relative Bioavailability of Three Formulations and Food Effect on GSK1322322 in Healthy Subjects

Start: Mar 2012Est. completion: May 201224 patients
Phase 1Completed
NCT00924911GSKGSK1322322

Relative Bioavailability Study in Healthy Subjects

Start: Apr 2009Est. completion: Jul 200920 patients
Phase 1Completed
NCT00828867GSK100 mg GSK investigational drug

Single Dose Escalation First Time in Human PK Study

Start: Nov 2008Est. completion: Dec 200941 patients
Phase 1Completed
NCT00358371GSKflucloxacillin 250 mg

Bioavailability Of Flucloxacillin Capsules (250 mg and 500 mg)

Start: Jan 2005Est. completion: Feb 200524 patients
Phase 1Completed
NCT07478471Human BioSciencesCollection of samples

Observational Study of Raxibacumab in Sporadic Cases of Systemic Anthrax

Start: May 2027Est. completion: Dec 203010 patients
N/ANot Yet Recruiting
NCT01587768GSKAntibiotic prescription during the study period between January 1, 2004 and December 31, 2009

WEUKBRE5555: IMI PROTECT(Work Package 2): Liver Injury & Antibiotics

Start: Nov 2011Est. completion: Jul 20141 patients
N/ACompleted

Phase Legend

PreclinicalLab & animal studies
Phase 1Safety & dosing
Phase 2Efficacy testing
Phase 3Large-scale trials
On MarketApproved & available

Key Insights

5 companies competing in this space

The information on this page is for informational purposes only and should not be used as a substitute for professional medical advice. Drug information is sourced from FDA, DailyMed, and other government databases. Adverse event data from FAERS does not establish causation. Always consult a healthcare professional for medical decisions.