Immunosuppression

6
Pipeline Programs
4
Companies
5
Clinical Trials
1
Approved Products

Pipeline by Development Stage

Preclinical
Phase 1
Phase 1/2
Phase 2
Phase 2/3
Phase 3
On Market
0
1
0
0
0
0
5
Early DiscoveryClinical DevelopmentMarket

Drug Modality Breakdown

Vaccine
2100%
+ 4 programs with unclassified modality

On Market (1)

Approved therapies currently available

Astellas
PROGRAFApproved
tacrolimus
Astellas
oral2018

Competitive Landscape

4 companies ranked by most advanced pipeline stage

Astellas
AstellasChina - Shenyang
3 programs
2
Once Daily TacrolimusPhase 41 trial
TacrolimusPhase 41 trial
The Differential Effects of 3 Different ImmunosuppressiveN/A1 trial
Active Trials
NCT00729248Completed12Est. Jan 2010
NCT01702207Completed36Est. Dec 2017
NCT00299221Completed150Est. Dec 2009
Abbott
AbbottABBOTT PARK, IL
1 program
1
Virosomal influenza vaccinePhase 4Vaccine1 trial
Active Trials
NCT00783380Completed304Est. Mar 2008
Boehringer Ingelheim
Boehringer IngelheimINGELHEIM, Germany
1 program
1
Virosomal influenza vaccinePhase 4Vaccine
Sandoz
SandozAustria - Kundl
1 program
1
Hydroxychloroquine Sulfate Tablets, 200 mgPhase 11 trial
Active Trials
NCT00946790CompletedEst. Dec 1993

Trial Timeline

Clinical trial activity over time

2021
2022
2023
2024
2025
2026
AstellasOnce Daily Tacrolimus
AbbottVirosomal influenza vaccine
AstellasTacrolimus
SandozHydroxychloroquine Sulfate Tablets, 200 mg
AstellasThe Differential Effects of 3 Different Immunosuppressive

Clinical Trials (5)

Total enrollment: 502 patients across 5 trials

NCT01702207AstellasOnce Daily Tacrolimus

Evaluation Of Switching From Twice Daily Tacrolimus To Once Daily Formulation On Cardiovascular Risk

Start: Oct 2012Est. completion: Dec 201736 patients
Phase 4Completed
NCT00783380AbbottVirosomal influenza vaccine

Influenza Vaccination in Immunocompromized Patients

Start: Oct 2005Est. completion: Mar 2008304 patients
Phase 4Completed

Safety Outcomes of Lower Immunosuppression Versus Traditional Immunosuppression in Heart Transplant Recipients

Start: Apr 2004Est. completion: Dec 2009150 patients
Phase 4Completed
NCT00946790SandozHydroxychloroquine Sulfate Tablets, 200 mg

To Demonstrate the Relative Bioavailability of Hydroxychloroquine Sulfate, 200 mg Tablets

Start: Jul 1993Est. completion: Dec 1993
Phase 1Completed
NCT00729248AstellasThe Differential Effects of 3 Different Immunosuppressive

The Differential Effects of 3 Different Immunosuppressive

Start: Jul 2008Est. completion: Jan 201012 patients
N/ACompleted

Phase Legend

PreclinicalLab & animal studies
Phase 1Safety & dosing
Phase 2Efficacy testing
Phase 3Large-scale trials
On MarketApproved & available

Key Insights

4 companies competing in this space