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Hysterectomy

4
Pipeline Programs
10
Companies
13
Clinical Trials
0
Approved Products

Pipeline by Development Stage

Preclinical
Phase 1
Phase 1/2
Phase 2
Phase 2/3
Phase 3
On Market
0
1
0
1
0
2
0
Early DiscoveryClinical DevelopmentMarket

Drug Modality Breakdown

Small Molecule
2100%
+ 7 programs with unclassified modality

Competitive Landscape

9 companies ranked by most advanced pipeline stage

Sharp Therapeutics
Sharp TherapeuticsPA - Pittsburgh
1 program
1
etoricoxibPhase 3Small Molecule
MSD
MSDIreland - Ballydine
1 program
1
etoricoxibPhase 3Small Molecule1 trial
Active Trials
NCT00373464Completed126Est. Mar 2007
Alkermes
AlkermesDUBLIN 4, Ireland
1 program
1
N1539Phase 22 trials
Active Trials
NCT01436032Terminated50Est. Mar 2012
NCT01084161Completed486Est. Jan 2011
Intuitive Surgical
Intuitive SurgicalCA - Sunnyvale
1 program
1
IS-001Phase 11 trial
Active Trials
NCT03006237Completed24Est. Dec 2017
Bayer
BayerLEVERKUSEN, Germany
1 program
Hysteroscopic device placement including EssureN/A1 trial
Active Trials
NCT02532361Completed10,578Est. Dec 2015
Verona Pharma
Verona PharmaUK - London
1 program
Robotic-assisted hysterectomyN/A1 trial
Active Trials
NCT06138197Completed150Est. Dec 2024
Human BioSciences
Human BioSciencesWV - Martinsburg
1 program
TestosteroneN/A1 trial
Active Trials
NCT00494208Completed270Est. Dec 2009
Innovation Pharmaceuticals
1 program
personal narrative bookN/A1 trial
Active Trials
NCT07430488Not Yet Recruiting156Est. Jan 2028
Johnson & Johnson
Johnson & JohnsonNEW BRUNSWICK, NJ
1 program
MorphinePHASE_35 trials
Active Trials
NCT00803283Terminated2Est. Dec 2008
NCT00766506Terminated108Est. Sep 2008
NCT00478023Completed854Est. Apr 2008
+2 more trials

Trial Timeline

Clinical trial activity over time

2021
2022
2023
2024
2025
2026
2027
2028
Johnson & JohnsonMorphine
Johnson & JohnsonMorphine
Johnson & JohnsonMorphine
AlkermesN1539
Johnson & JohnsonMorphine
Johnson & JohnsonMorphine
MSDetoricoxib
AlkermesN1539
Intuitive SurgicalIS-001
Innovation Pharmaceuticalspersonal narrative book
Verona PharmaRobotic-assisted hysterectomy
BayerHysteroscopic device placement including Essure
Human BioSciencesTestosterone

Clinical Trials (13)

Total enrollment: 13,500 patients across 13 trials

An Efficacy and Safety Study to Compare Fentanyl Ionsys and Routine Care With Intravenous (IV) Morphine Patient-controlled Analgesia (PCA) in Participants Who Have Undergone Elective Major Abdominal or Orthopedic Surgery

Start: May 2008Est. completion: Sep 2008108 patients
Phase 4Terminated

A Study to Compare Patient-controlled Pain Medications Delivered Either Through the Skin or Intravenously

Start: Jun 2004Est. completion: Apr 2005657 patients
Phase 4Completed

An Efficacy and Safety Study of Transdermal Therapeutic System (TTS)-Fentanyl in Thai Participants With Chronic Non-Malignant Pain

Start: Apr 2004Est. completion: Mar 200839 patients
Phase 4Completed

Efficacy, Safety and Tolerability Study of N1539 in Subjects After Abdominal Laparoscopic Surgery

Start: Oct 2011Est. completion: Mar 201250 patients
Phase 3Terminated

A Study to Compare Safety and Efficacy of Osmotic Release Oral Syytem (OROS) Hydromorphone Hydrochloride (HCl) With Morphine Sustain Release (SR) in Participants With Cancer Pain

Start: Nov 2008Est. completion: Dec 20082 patients
Phase 3Terminated

A Study to Evaluate the Efficacy and Safety of Tapentadol (CG5503) in the Treatment of Acute Pain After Abdominal Hysterectomy

Start: May 2007Est. completion: Apr 2008854 patients
Phase 3Completed
NCT00373464MSDetoricoxib

Etoricoxib for Routine Post-operative Pain Prophylaxis in Laparoscopic Surgery

Start: Mar 2006Est. completion: Mar 2007126 patients
Phase 3Completed

Study to Evaluate the Efficacy, Safety and Tolerability of N1539

Start: Mar 2010Est. completion: Jan 2011486 patients
Phase 2Completed

IS-001 Injection Phase-1 Safety, Tolerance and Pharmacokinetics

Start: Dec 2016Est. completion: Dec 201724 patients
Phase 1Completed

Effect of Reading a Personal Narrative Book on Emotional Regulation in Women of Childbearing Age Undergoing Hysterectomy (RELIEF)

Start: Apr 2026Est. completion: Jan 2028156 patients
N/ANot Yet Recruiting
NCT06138197Verona PharmaRobotic-assisted hysterectomy

Comparison of Three Robotic Platforms for Hysterectomy

Start: Jan 2024Est. completion: Dec 2024150 patients
N/ACompleted
NCT02532361BayerHysteroscopic device placement including Essure

Proportion of Hysterectomy After Female Sterilization

Start: Aug 2015Est. completion: Dec 201510,578 patients
N/ACompleted

TDSM- Testosterone Dose Response in Surgically Menopausal Women

Start: Jan 2009Est. completion: Dec 2009270 patients
N/ACompleted

Phase Legend

PreclinicalLab & animal studies
Phase 1Safety & dosing
Phase 2Efficacy testing
Phase 3Large-scale trials
On MarketApproved & available

Key Insights

2 late-stage (Phase 3) programs, potential near-term approvals
10 companies competing in this space

The information on this page is for informational purposes only and should not be used as a substitute for professional medical advice. Drug information is sourced from FDA, DailyMed, and other government databases. Adverse event data from FAERS does not establish causation. Always consult a healthcare professional for medical decisions.