Hypogammaglobulinemia

3
Pipeline Programs
3
Companies
5
Clinical Trials
1 recruiting
0
Approved Products

Pipeline by Development Stage

Preclinical
Phase 1
Phase 1/2
Phase 2
Phase 2/3
Phase 3
On Market
0
0
0
1
0
2
0
Early DiscoveryClinical DevelopmentMarket

Competitive Landscape

3 companies ranked by most advanced pipeline stage

Grifols
GrifolsNEW YORK, NY
3 programs
1
1
XembifyPhase 31 trial
IVIGPhase 21 trial
IVIGN/A1 trial
Active Trials
NCT02043379CompletedEst. Jun 2015
NCT00115778CompletedEst. Aug 2010
NCT05645107RecruitingEst. Jun 2026
Octapharma
OctapharmaAustria - Vienna
1 program
1
Panzyga, 10% Intravenous SolutionPhase 31 trial
Active Trials
NCT07220915Not Yet Recruiting360Est. Dec 2029
CSL Behring
CSL BehringIL - Bradley
1 program
subcutaneous immunoglobulinN/A1 trial
Active Trials
NCT03401268Completed20Est. May 2019

Trial Timeline

Clinical trial activity over time

2021
2022
2023
2024
2025
2026
2027
2028
2029
OctapharmaPanzyga, 10% Intravenous Solution
GrifolsXembify
GrifolsIVIG
CSL Behringsubcutaneous immunoglobulin
GrifolsIVIG

Clinical Trials (5)

Total enrollment: 380 patients across 5 trials

NCT07220915OctapharmaPanzyga, 10% Intravenous Solution

Supporting Weak Immune System During Autoimmune Therapy: Testing Panzyga to Prevent Infections

Start: Dec 2025Est. completion: Dec 2029360 patients
Phase 3Not Yet Recruiting

A Study to Evaluate Efficacy, Safety, and PK of XEMBIFY®+Standard Medical Treatment (SMT) Compared to Placebo+SMT to Prevent Infections in Participants With HGG and Recurrent or Severe Infections Associated With B-cell Chronic Lymphocytic Leukemia, Multiple Myeloma, and Non-Hodgkin Lymphoma

Start: Dec 2022Est. completion: Jun 2026
Phase 3Recruiting

Intravenous Immunoglobulin (IVIG) in Lung Transplantation

Start: Jun 2005Est. completion: Aug 2010
Phase 2Completed
NCT03401268CSL Behringsubcutaneous immunoglobulin

Subcutaneous Ig in Allogeneic Stem Cell Transplant Recipients

Start: Feb 2018Est. completion: May 201920 patients
N/ACompleted

Post-bypass Prophylactic IVIG in Infants and Neonates

Start: May 2014Est. completion: Jun 2015
N/ACompleted

Phase Legend

PreclinicalLab & animal studies
Phase 1Safety & dosing
Phase 2Efficacy testing
Phase 3Large-scale trials
On MarketApproved & available

Key Insights

2 late-stage (Phase 3) programs — potential near-term approvals
1 actively recruiting trials targeting 380 patients
3 companies competing in this space