Hip Osteoarthritis

Pipeline Programs

Companies

Clinical Trials

2 recruiting

Approved Products

Pipeline by Development Stage

Preclinical

Phase 1

Phase 1/2

Phase 2

Phase 2/3

Phase 3

On Market

Early DiscoveryClinical DevelopmentMarket

On Market (1)

Approved therapies currently available

RECLASTApproved

zoledronic acid

Novartis

intravenous2007

Competitive Landscape

14 companies ranked by most advanced pipeline stage

Pre

P1/2

P2/3

Mkt

Zimmer BiometFL - Jacksonville

6 programs

TaperlocPhase 41 trial

Femoral StemN/A1 trial

G7 Dual Mobility with Vivacit-E bearingN/A1 trial

G7 Freedom Constrained LinersN/A1 trial

Taperloc Complete Microplasty stemN/A1 trial

+1 more programs

Active Trials

NCT01883492Terminated153Est. Mar 2019

NCT05548972Enrolling By Invitation358Est. Aug 2037

NCT04093739Withdrawn0Est. Dec 2029

+3 more trials

StrykerCA - San Jose

4 programs

zoledronic acidPhase 4

Insignia uncemented Hip StemN/A1 trial

Manual Total Hip ReplacementN/A

Symax uncemented hip stemN/A1 trial

Active Trials

NCT05144191Active Not Recruiting313Est. Apr 2034

NCT03469687Completed80Est. Oct 2010

Nordic PharmaFrance - Paris

2 programs

zoledronic acidPhase 4

Manual Total Hip ReplacementN/A1 trial

Active Trials

NCT05507073Unknown50Est. Dec 2024

NovartisBASEL, Switzerland

1 program

zoledronic acidPHASE_4

SandozAustria - Kundl

1 program

zoledronic acidPhase 41 trial

Active Trials

NCT01218035Completed49Est. Jun 2011

MedactaSwitzerland - Castel San Pietro

2 programs

MPact CupN/A1 trial

total hip arthroplastyN/A1 trial

Active Trials

NCT03897595Completed187Est. Mar 2022

NCT04199390Completed130Est. Oct 2019

Anika TherapeuticsMA - Bedford

1 program

CingalN/A1 trial

Active Trials

NCT04084704Completed100Est. Jun 2023

BiocorpFrance - Issoire

1 program

Conventional Home-based Rehabilitation PlanN/A1 trial

Active Trials

NCT04176315Terminated38Est. Dec 2020

Innovation PharmaceuticalsMA - Wakefield

1 program

Full revisionN/A1 trial

Active Trials

NCT04541693Active Not Recruiting8Est. Dec 2027

EmbodyVA - Norfolk

1 program

H1 Hip Resurfacing ArthroplastyN/A1 trial

Active Trials

NCT03326804Active Not Recruiting250Est. Mar 2033

CorinUK - Cirencester

1 program

MiniHipN/A1 trial

Active Trials

NCT02174965Unknown50Est. Sep 2022

Colorado TherapeuticsCO - Louisville

1 program

PRPN/A1 trial

Active Trials

NCT01920152Completed38Est. Dec 2019

Next ScienceAustralia - Sydney

1 program

XPERIENCE Advanced Surgical IrrigationN/A1 trial

Active Trials

NCT05543941Recruiting7,600Est. Dec 2027

One BiosciencesFrance - Paris

1 program

total hip arthroplastyN/A

Trial Timeline

Clinical trial activity over time

2021

2022

2023

2024

2025

2026

2027

2028

2029

2030

2031

Sandozzoledronic acid

Zimmer BiometTaperloc

Zimmer BiometZ1 Femoral Hip System

Next ScienceXPERIENCE Advanced Surgical Irrigation

Zimmer BiometG7 Dual Mobility with Vivacit-E bearing

Zimmer BiometG7 Freedom Constrained Liners

StrykerInsignia uncemented Hip Stem

Nordic PharmaManual Total Hip Replacement

Anika TherapeuticsCingal

BiocorpConventional Home-based Rehabilitation Plan

Innovation PharmaceuticalsFull revision

Medactatotal hip arthroplasty

EmbodyH1 Hip Resurfacing Arthroplasty

Zimmer BiometTaperloc Complete Microplasty stem

Colorado TherapeuticsPRP

Showing 15 of 19 trials with date data

Clinical Trials (19)

Total enrollment: 9,659 patients across 19 trials

NCT01218035 Sandozzoledronic acid

Efficacy of Zoledronic Acid in Enhancement of Early Stability of Cementless Primary Hip Prosthesis

Start: May 2007Est. completion: Jun 201149 patients

Phase 4Completed

NCT02321683 Zimmer BiometTaperloc

Evaluation of a New Coating in Cement Less Femoral Stems

Start: Dec 2003Est. completion: Dec 200855 patients

Phase 4Completed

NCT07104279 Zimmer BiometZ1 Femoral Hip System

Z1 Hip System: Post-Market Clinical Follow Up Study

Start: Oct 2025Est. completion: Aug 2031150 patients

N/ARecruiting

NCT05543941 Next ScienceXPERIENCE Advanced Surgical Irrigation

Evaluating XPERIENCE™ Advanced Surgical Irrigation

Start: Apr 2023Est. completion: Dec 20277,600 patients

N/ARecruiting

NCT05548972 Zimmer BiometG7 Dual Mobility with Vivacit-E bearing

G7 Dual Mobility With Vivacit-E or Longevity PMCF

Start: Mar 2023Est. completion: Aug 2037358 patients

N/AEnrolling By Invitation

NCT04093739 Zimmer BiometG7 Freedom Constrained Liners

MDR - G7 Neutral and G7 Freedom Constrained Neutral Acetabular Liners

Start: Apr 2022Est. completion: Dec 20290

N/AWithdrawn

NCT05144191 StrykerInsignia uncemented Hip Stem

Insignia™ Hip Stem Outcomes Study

Start: Feb 2022Est. completion: Apr 2034313 patients

N/AActive Not Recruiting

NCT05507073 Nordic PharmaManual Total Hip Replacement

A Comparison of Impingement Free Range of Motion With CT Scan After Manual and Robotic Total Hip Replacement

Start: Apr 2021Est. completion: Dec 202450 patients

N/AUnknown

NCT04084704 Anika TherapeuticsCingal

A Prospective Evaluation of the Cingal Injection for Hip Osteoarthritis

Start: Sep 2020Est. completion: Jun 2023100 patients

N/ACompleted

NCT04176315 BiocorpConventional Home-based Rehabilitation Plan

Usability and Effectiveness of ReHub in Patients After Total Hip Arthroplasty

Start: Dec 2019Est. completion: Dec 202038 patients

N/ATerminated

NCT04541693 Innovation PharmaceuticalsFull revision

REDAPT Revision Hip System With RSA

Start: Jan 2019Est. completion: Dec 20278 patients

N/AActive Not Recruiting

NCT04199390 Medactatotal hip arthroplasty

Physical Therapy Following Total Hip Arthroplasty

Start: Jul 2018Est. completion: Oct 2019130 patients

N/ACompleted

NCT03326804 EmbodyH1 Hip Resurfacing Arthroplasty

H1 Hip Resurfacing Arthroplasty

Start: Sep 2017Est. completion: Mar 2033250 patients

N/AActive Not Recruiting

NCT03409666 Zimmer BiometTaperloc Complete Microplasty stem

Randomized Controlled RSA Study Comparing the Taperloc Complete Versus the Taperloc Complete Microplasty.

Start: May 2017Est. completion: Nov 202050 patients

N/ACompleted

NCT01920152 Colorado TherapeuticsPRP

Platelet Rich Plasma vs Hyaluronic-Acid in Hip OA (Osteoarthritis)

Start: Aug 2013Est. completion: Dec 201938 patients

N/ACompleted

NCT01883492 Zimmer BiometFemoral Stem

A Prospective Multi-center Study on Total Hip Arthroplasty With E1

Start: Mar 2013Est. completion: Mar 2019153 patients

N/ATerminated

NCT03897595 MedactaMPact Cup

Assess the Mid-term Performance of the Mpact Cup in Subjects Requiring Total Hip Arthroplasty

Start: Oct 2012Est. completion: Mar 2022187 patients

N/ACompleted

NCT02174965 CorinMiniHip

Wear and Migration in the Corin Mini-Hip/Metafix and ECIMA Polyethylene

Start: Sep 2012Est. completion: Sep 202250 patients

N/AUnknown

NCT03469687 StrykerSymax uncemented hip stem

Symax International Study

Start: Nov 2004Est. completion: Oct 201080 patients

N/ACompleted

Phase Legend

Preclinical— Lab & animal studies

Phase 1— Safety & dosing

Phase 2— Efficacy testing

Phase 3— Large-scale trials

On Market— Approved & available

Key Insights

2 actively recruiting trials targeting 9,659 patients

15 companies competing in this space

The information on this page is for informational purposes only and should not be used as a substitute for professional medical advice. Drug information is sourced from FDA, DailyMed, and other government databases. Adverse event data from FAERS does not establish causation. Always consult a healthcare professional for medical decisions.