High Blood Pressure

Pipeline Programs

Companies

Clinical Trials

Approved Products

Pipeline by Development Stage

Preclinical

Phase 1

Phase 1/2

Phase 2

Phase 2/3

Phase 3

On Market

Early DiscoveryClinical DevelopmentMarket

Drug Modality Breakdown

Small Molecule

1100%

+ 5 programs with unclassified modality

Competitive Landscape

4 companies ranked by most advanced pipeline stage

Pre

P1/2

P2/3

Mkt

SandozAustria - Kundl

3 programs

Aliskiren and HCTZPhase 4

AliskirenPhase 2

NadololPHASE_1Small Molecule

CVRxMN - Minneapolis

1 program

BAROSTIM NEO SystemN/A1 trial

Active Trials

NCT01471834Active Not Recruiting40Est. Aug 2026

Human BioSciencesWV - Martinsburg

1 program

Whey ProteinN/A1 trial

Active Trials

NCT00659672Completed35Est. Feb 2009

EisaiChina - Liaoning

1 program

BunazosinPHASE_41 trial

Active Trials

NCT00130156Completed93Est. Mar 2009

Trial Timeline

Clinical trial activity over time

2021

2022

2023

2024

2025

2026

EisaiBunazosin

CVRxBAROSTIM NEO System

Human BioSciencesWhey Protein

Clinical Trials (3)

Total enrollment: 168 patients across 3 trials

NCT00130156 EisaiBunazosin

Effects of Combination Therapy With Alpha-1 Blocker (Bunazosin or Doxazosin) in the Treatment of Patients With Mild to Moderate Essential Hypertension

Start: Oct 2005Est. completion: Mar 200993 patients

Phase 4Completed

NCT01471834 CVRxBAROSTIM NEO System

Verification of the Efficacy and Safety of the BAROSTIM NEO System in the Treatment of Drug Resistant Hypertension

Start: Jun 2011Est. completion: Aug 202640 patients

N/AActive Not Recruiting

NCT00659672 Human BioSciencesWhey Protein

Effect of Whey Protein on Blood Pressure

Start: Sep 2008Est. completion: Feb 200935 patients

N/ACompleted

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Phase Legend

Preclinical— Lab & animal studies

Phase 1— Safety & dosing

Phase 2— Efficacy testing

Phase 3— Large-scale trials

On Market— Approved & available

Key Insights

5 companies competing in this space

The information on this page is for informational purposes only and should not be used as a substitute for professional medical advice. Drug information is sourced from FDA, DailyMed, and other government databases. Adverse event data from FAERS does not establish causation. Always consult a healthcare professional for medical decisions.