Hemophagocytic Lymphohistiocytoses
2
Pipeline Programs
1
Companies
2
Clinical Trials
1
Approved Products
Pipeline by Development Stage
Preclinical
Phase 1
Phase 1/2
Phase 2
Phase 2/3
Phase 3
On Market
0
0
0
0
1
0
1
Early DiscoveryClinical DevelopmentMarket
On Market (1)
Approved therapies currently available
U
GAMIFANTApproved
emapalumab-lzsg
Unknown CompanyInterferon gamma Blocker [EPC]injection2018
Competitive Landscape
1 companies ranked by most advanced pipeline stage
Swedish Orphan BiovitrumMA - Waltham
2 programs1
Emapalumab-LzsgPhase 2/31 trial
Blood Draws Data CollectionN/A1 trial
Active Trials
Trial Timeline
Clinical trial activity over time
2021
2022
2023
2024
2025
2026
Swedish Orphan BiovitrumEmapalumab-Lzsg
Swedish Orphan BiovitrumBlood Draws Data Collection
Clinical Trials (2)
A Study to Evaluate the Efficacy, Safety and Pharmacokinetics of Emapalumab in Adult Patients With HLH
Start: Jun 2020Est. completion: Jun 2021
Phase 2/3Terminated
Evaluation of IFNγ and Inflammatory Mediators in Patients With Hemophagocytic Lymphohistiocytosis
Start: Dec 2016Est. completion: Oct 2019
N/ACompleted
Phase Legend
Preclinical— Lab & animal studies
Phase 1— Safety & dosing
Phase 2— Efficacy testing
Phase 3— Large-scale trials
On Market— Approved & available
Key Insights
1 companies competing in this space