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Hearing Loss, Sensorineural

2
Pipeline Programs
11
Companies
18
Clinical Trials
1 recruiting
0
Approved Products

Pipeline by Development Stage

Preclinical
Phase 1
Phase 1/2
Phase 2
Phase 2/3
Phase 3
On Market
0
1
0
1
0
0
0
Early DiscoveryClinical DevelopmentMarket

Competitive Landscape

10 companies ranked by most advanced pipeline stage

AudioCure Pharma
AudioCure PharmaGermany - Berlin
1 program
1
AC102Phase 21 trial
Active Trials
NCT05776459Active Not Recruiting210Est. Jul 2026
Oregon Therapeutics
Oregon TherapeuticsFrance - Paris
1 program
1
FludrocortisonePhase 11 trial
Active Trials
NCT01186185Terminated5Est. Mar 2016
Cochlear
CochlearAustralia - Macquarie Park
7 programs
CI532N/A1 trial
CP950 OTE Sound processorN/A1 trial
Cochlear ImplantN/A1 trial
Cochlear implantationN/A1 trial
Cochlear™ Nucleus® SystemN/A1 trial
+2 more programs
Active Trials
NCT03007472Completed96Est. Mar 2020
NCT03613909Completed23Est. Nov 2016
NCT04987021Completed15Est. Jan 2022
+4 more trials
Oticon
OticonDenmark - Smørum
3 programs
Neuro 1 & Neuro 2N/A1 trial
Neuro ZtiN/A1 trial
PupillometryN/A1 trial
Active Trials
NCT03756337Completed20Est. Jan 2020
NCT02941627Completed53Est. Nov 2019
NCT05586555Terminated13Est. Nov 2023
iotaMotion
iotaMotionIA - Iowa City
2 programs
iotaSOFT Insertion SystemN/A1 trial
iotaSOFT Insertion System with AIMN/A1 trial
Active Trials
NCT06106373Completed20Est. Jul 2025
NCT06664710Recruiting10Est. Aug 2025
Colorado Therapeutics
Colorado TherapeuticsCO - Louisville
1 program
CROSN/A1 trial
Active Trials
NCT03867396Completed40Est. Feb 2021
Syneos Health
Syneos HealthNC - Morrisville
1 program
Cochlear implantationN/A
International Stem Cell
1 program
High frequency pure tone audiometryN/A1 trial
Active Trials
NCT04270916Suspended46Est. Sep 2020
Innovation Pharmaceuticals
1 program
uAudN/A1 trial
Active Trials
NCT05043207Unknown250Est. Dec 2024
Biogen
BiogenCAMBRIDGE, MA
1 program
PF-04958242PHASE_11 trial
Active Trials
NCT01518920Completed44Est. Feb 2013

Trial Timeline

Clinical trial activity over time

2021
2022
2023
2024
2025
2026
2027
2028
AudioCure PharmaAC102
Oregon TherapeuticsFludrocortisone
BiogenPF-04958242
CochlearStandard Electrical Categorical Loudness Scaling task
CochlearCochlear™ Nucleus® System
CochlearProgram using default MAP
iotaMotioniotaSOFT Insertion System with AIM
OticonPupillometry
Innovation PharmaceuticalsuAud
iotaMotioniotaSOFT Insertion System
CochlearCochlear Implant
International Stem CellHigh frequency pure tone audiometry
OticonNeuro 1 & Neuro 2
CochlearCochlear implantation
Colorado TherapeuticsCROS

Showing 15 of 18 trials with date data

Clinical Trials (18)

Total enrollment: 936 patients across 18 trials

NCT05776459AudioCure PharmaAC102

Efficacy and Safety of AC102 Compared to Steroids in Adults With Idiopathic Sudden Sensorineural Hearing Loss (ISSNHL)

Start: Oct 2022Est. completion: Jul 2026210 patients
Phase 2Active Not Recruiting
NCT01186185Oregon TherapeuticsFludrocortisone

Fludrocortisone for Sudden Hearing Loss

Start: Aug 2012Est. completion: Mar 20165 patients
Phase 1Terminated
NCT01518920BiogenPF-04958242

A Study Of The Effects Of PF-04958242 In Subjects With Age-Related Hearing Loss

Start: Dec 2011Est. completion: Feb 201344 patients
Phase 1Completed
NCT07077070CochlearStandard Electrical Categorical Loudness Scaling task

Investigating Electrical Categorical Loudness Scaling Using a Mobile Research App in Experienced Adult Cochlear Implant Participants

Start: Oct 2025Est. completion: Dec 202520 patients
N/ACompleted
NCT06293482CochlearCochlear™ Nucleus® System

Safety and Effectiveness of Cochlear Implantation in an Expanded Adult Population

Start: Sep 2024Est. completion: Oct 202850 patients
N/AActive Not Recruiting
NCT06298396CochlearProgram using default MAP

Investigating Stimulation Parameter and Electrode Mode Changes on Speech Perception in Experienced Adult Cochlear Implant Recipients

Start: May 2024Est. completion: Dec 202420 patients
N/ACompleted
NCT06664710iotaMotioniotaSOFT Insertion System with AIM

Evaluation of the Automated Integration of a Robotics and ECochG System for Use With Cochlear Implant Surgery

Start: Jan 2024Est. completion: Aug 202510 patients
N/ARecruiting
NCT05586555OticonPupillometry

A Monocentric Study Evaluating Pupillometry as an Objective Measurement for CI Fittings

Start: May 2023Est. completion: Nov 202313 patients
N/ATerminated
NCT05043207Innovation PharmaceuticalsuAud

A Study Protocol for the Validation of UAud in a Clinical Setting.

Start: Sep 2022Est. completion: Dec 2024250 patients
N/AUnknown
NCT06106373iotaMotioniotaSOFT Insertion System

iotaSOFT Pediatric Study

Start: May 2022Est. completion: Jul 202520 patients
N/ACompleted
NCT04987021CochlearCochlear Implant

An Actual Use, Open-label Study Assessing Usability of Remote Assist to Program Cochlear Implant Recipients

Start: Aug 2021Est. completion: Jan 202215 patients
N/ACompleted
NCT04270916International Stem CellHigh frequency pure tone audiometry

Prevalence and Impact on QoL From Ototoxicity in Cancer Survivors

Start: Feb 2020Est. completion: Sep 202046 patients
N/ASuspended
NCT03756337OticonNeuro 1 & Neuro 2

Neuro 1 vs. Neuro 2 Sound Processors

Start: Nov 2019Est. completion: Jan 202020 patients
N/ACompleted
NCT03382769CochlearCochlear implantation

Hearing Loss in Older Adults Study

Start: Mar 2019Est. completion: Jan 20201 patients
N/ATerminated
NCT03867396Colorado TherapeuticsCROS

Evaluation of Speech-in-noise Performance in Cochlear Implant Recipients With a CROS Device on the Contralateral Ear

Start: Jan 2019Est. completion: Feb 202140 patients
N/ACompleted
NCT03007472CochlearCI532

Clinical Evaluation of the Cochlear Nucleus CI532 Cochlear Implant in Adults

Start: Feb 2017Est. completion: Mar 202096 patients
N/ACompleted
NCT02941627OticonNeuro Zti

The Neuro Zti Cochlear Implant System Efficacy and Safety in Adults

Start: Feb 2017Est. completion: Nov 201953 patients
N/ACompleted
NCT03613909CochlearCP950 OTE Sound processor

Acceptance of the CP950 Sound Processor

Start: Nov 2015Est. completion: Nov 201623 patients
N/ACompleted

Phase Legend

Preclinical— Lab & animal studies
Phase 1— Safety & dosing
Phase 2— Efficacy testing
Phase 3— Large-scale trials
On Market— Approved & available

Key Insights

1 actively recruiting trials targeting 936 patients
11 companies competing in this space

The information on this page is for informational purposes only and should not be used as a substitute for professional medical advice. Drug information is sourced from FDA, DailyMed, and other government databases. Adverse event data from FAERS does not establish causation. Always consult a healthcare professional for medical decisions.