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Hearing Loss

7
Pipeline Programs
19
Companies
50
Clinical Trials
8 recruiting
0
Approved Products

Pipeline by Development Stage

Preclinical
Phase 1
Phase 1/2
Phase 2
Phase 2/3
Phase 3
On Market
0
3
0
2
0
0
2
Early DiscoveryClinical DevelopmentMarket

Competitive Landscape

18 companies ranked by most advanced pipeline stage

Advanced Bionics
Advanced BionicsCA - Valencia
12 programs
2
HiRes 90K Bionic Ear SystemPhase 41 trial
HiResolution Bionic Ear SystemPhase 41 trial
Cochlear Implant HeadpieceN/A
Cochlear Implant Sound Processor - Naída Q90N/A
Cochlear implant processor Sky CITM M90N/A1 trial
+7 more programs
Active Trials
NCT06400992Recruiting20Est. Jun 2027
NCT02189798Terminated67Est. Mar 2022
NCT02811549Completed24Est. Mar 2020
+6 more trials
Sound Pharmaceuticals
6 programs
2
1
EbselenPhase 21 trial
Noise ReductionPhase 11 trial
SPI-1005Phase 11 trial
Current Primary Care Referral ProcessN/A1 trial
Current Primary Care Referral ProcessN/A1 trial
+1 more programs
Active Trials
NCT03662256Completed155Est. Feb 2020
NCT03309553Completed1,481Est. Feb 2020
NCT04777669Unknown100Est. Mar 2023
+2 more trials
Sensorion
SensorionFrance - Montpellier
1 program
1
SENS-401Phase 21 trial
Active Trials
NCT05258773Completed28Est. May 2024
Otologic Pharmaceutics
Otologic PharmaceuticsOK - Oklahoma City
1 program
1
HPN-07Phase 11 trial
Active Trials
NCT02259595Completed32Est. Feb 2015
Cochlear
CochlearAustralia - Macquarie Park
41 programs
A New Sound ProcessorN/A1 trial
Active Osseointegrated Steady-State Implant SystemN/A1 trial
Baha® flange fixtureN/A1 trial
Bass and TrebleN/A1 trial
CI532 cochlear implantN/A1 trial
+36 more programs
Active Trials
NCT02934373Withdrawn0
NCT04754477Completed20Est. Mar 2022
NCT05058066Completed51Est. Sep 2020
+38 more trials
Oticon
OticonDenmark - Smørum
10 programs
Abbreviated Profile Hearing Aid BenefitN/A1 trial
Abbreviated Profile of Hearing Aid BenefitN/A1 trial
BAHSN/A1 trial
Device AN/A1 trial
Pediatric Performance and Satisfaction of Oticon Medical Ponto on Softband.N/A1 trial
+5 more programs
Active Trials
NCT04279236Completed64Est. Dec 2024
NCT04310202Completed50Est. Dec 2023
NCT06421766Completed234Est. Sep 2024
+6 more trials
Colorado Therapeutics
Colorado TherapeuticsCO - Louisville
4 programs
HA-HCPN/A1 trial
Hearing AidsN/A1 trial
Hearing AidsN/A1 trial
augmentative and alternative communication technologyN/A1 trial
Active Trials
NCT06689865Recruiting280Est. Mar 2029
NCT03345654Completed42Est. Nov 2024
NCT05653999Completed36Est. May 2025
+1 more trials
Alliance Pharmaceuticals
2 programs
Baha sound processor BA400N/A1 trial
Remote fittingN/A
Active Trials
NCT04611698Completed1Est. Dec 2017
Oregon Therapeutics
Oregon TherapeuticsFrance - Paris
1 program
Audiobooks for hearing loss AppN/A1 trial
Active Trials
NCT04231396Completed27Est. Sep 2021
Human BioSciences
Human BioSciencesWV - Martinsburg
1 program
Auditory-Cognitive TrainingN/A1 trial
Active Trials
NCT05176561Enrolling By Invitation30Est. Apr 2027
Gateway Biotechnology
1 program
Distortion product otoacoustic emissionsN/A1 trial
Active Trials
NCT04322747Withdrawn0Est. Feb 2022
Philips
PhilipsNetherlands - Amsterdam
1 program
Ear-worn prototype devicesN/A1 trial
Active Trials
NCT05350046Completed30Est. Apr 2023
Relief Therapeutics
Relief TherapeuticsSwitzerland - Geneva
1 program
Lyric Hearing Aid- Experimental DesignN/A1 trial
Active Trials
NCT05274165Completed25Est. Sep 2022
Physical Sciences
Physical SciencesMA - Andover
1 program
Objective speech response detectionN/A1 trial
Active Trials
NCT03279367Completed20Est. Sep 2018
Connect Biopharma
Connect BiopharmaSAN DIEGO, CA
1 program
Remote fittingN/A1 trial
Active Trials
NCT02589561Completed60Est. Dec 2016
Purdue Pharma
Purdue PharmaCT - Stamford
1 program
Sudden Sound Reduction SettingN/A1 trial
Active Trials
NCT06340919Unknown60Est. May 2025
Envoy Medical
Envoy MedicalMN - White Bear Lake
1 program
The Esteem Hearing ImplantN/A1 trial
Active Trials
NCT02666222Completed51Est. Mar 2015
Knight Therapeutics
Knight TherapeuticsQC - Montréal
1 program
Autologous Human Umbilical Cord BloodPHASE_11 trial
Active Trials
NCT01343394Withdrawn0Est. Apr 2016

Trial Timeline

Clinical trial activity over time

2021
2022
2023
2024
2025
2026
2027
2028
2029
Advanced BionicsHiResolution Bionic Ear System
Advanced BionicsHiRes 90K Bionic Ear System
Sound PharmaceuticalsEbselen
SensorionSENS-401
Sound PharmaceuticalsNoise Reduction
Otologic PharmaceuticsHPN-07
Knight TherapeuticsAutologous Human Umbilical Cord Blood
Sound PharmaceuticalsSPI-1005
CochlearCochlear Nucleus Nexa Cochlear implant
OticonThe Sentio System: Post-market Evaluation of Safety and Performance in Adolescents
OticonPonto implantation
CochlearCochlear implant
Advanced BionicsCochlear implant processor Sky CITM M90
Colorado TherapeuticsHA-HCP
CochlearCochlear™ Remote care

Showing 15 of 49 trials with date data

Clinical Trials (50)

Total enrollment: 3,575 patients across 50 trials

NCT00424307Advanced BionicsHiResolution Bionic Ear System

Bilateral Cochlear Implant Benefit in Young Children

Start: Jan 2007Est. completion: Apr 201260 patients
Phase 4Unknown
NCT00205881Advanced BionicsHiRes 90K Bionic Ear System

Bilateral Benefit in Adult Users of the HiRes 90K Bionic Ear System

Start: Oct 2004Est. completion: May 200932 patients
Phase 4Completed

SPI-1005 in Adults Receiving Cochlear Implant

Start: Aug 2025Est. completion: Dec 202540 patients
Phase 2Recruiting

Evaluation of the Presence of SENS-401 in the Perilymph

Start: Aug 2022Est. completion: May 202428 patients
Phase 2Completed

Removing Background Talker Noise for Cochlear Implant Users

Start: Apr 2020Est. completion: Mar 2023100 patients
Phase 1Unknown

Study to Determine the Safety, Tolerability, and Pharmacokinetic Profile of HPN-07 and HPN-07 Plus NAC

Start: Oct 2014Est. completion: Feb 201532 patients
Phase 1Completed
NCT01343394Knight TherapeuticsAutologous Human Umbilical Cord Blood

Safety of Autologous Human Umbilical Cord Blood Mononuclear Fraction to Treat Acquired Hearing Loss in Children

Start: Apr 2011Est. completion: Apr 20160
Phase 1Withdrawn

Study to Evaluate the Safety and Pharmacokinetics of SPI-1005

Start: May 2006Est. completion: Aug 200632 patients
Phase 1Completed
NCT02934373CochlearA New Sound Processor

Evaluation of Subjective Ratings on a New Sound Processor and Compatible Products

0
N/AWithdrawn
NCT07338864CochlearCochlear Nucleus Nexa Cochlear implant

A Study to Evaluate Clinical Benefit, Performance and Safety of Cochlear Implants in Adults

Start: May 2026Est. completion: Sep 202866 patients
N/ANot Yet Recruiting
NCT06844071OticonThe Sentio System: Post-market Evaluation of Safety and Performance in Adolescents

The Sentio System: Post-market Evaluation of Safety and Performance in Adolescents

Start: Aug 2025Est. completion: Aug 202725 patients
N/ARecruiting
NCT06930781OticonPonto implantation

Evaluation of Clinical Outcomes of Ponto Procedures Performed in Settings Outside the Main Operating Room (i.e. Out-of-OR)

Start: May 2025Est. completion: Dec 2026270 patients
N/ARecruiting
NCT06598059CochlearCochlear implant

Safety and Efficacy of a Drug Eluting Slim Modiolar Electrode Array

Start: Jan 2025Est. completion: Sep 202656 patients
N/AActive Not Recruiting
NCT06400992Advanced BionicsCochlear implant processor Sky CITM M90

Investigation of Sky Automatic Technologies in Pediatrics

Start: Dec 2024Est. completion: Jun 202720 patients
N/ARecruiting

Innovations in Hearing Accessibility and Technology (IHAT) Study

Start: Nov 2024Est. completion: Mar 2029280 patients
N/ARecruiting
NCT05552118CochlearCochlear™ Remote care

Speech Performance and Clinic Efficiency With Remote Care Compared With Standard of Care in Adults With a Cochlear Implant in the First 12 Months Post-activation

Start: Mar 2024Est. completion: Sep 2026148 patients
N/AActive Not Recruiting

Retrospective Study of Outcomes With 3 mm Implant for Percutaneous BAHS Procedures

Start: Mar 2024Est. completion: Sep 2024234 patients
N/ACompleted
NCT06100393CochlearInvestigational Pre-Processing Algorithm

New Algorithms to Signal Processing for Speech Enhancement in Adult Cochlear Implant Recipients.

Start: Feb 2024Est. completion: Oct 2026150 patients
N/ARecruiting
NCT06340919Purdue PharmaSudden Sound Reduction Setting

Hearing Aid Algorithms for Sudden Sounds

Start: Feb 2024Est. completion: May 202560 patients
N/AUnknown
NCT06098482CochlearMobile Research App

An Investigation to Validate Speech Perception Assessment for Adult Cochlear Recipients Using a Mobile Research App

Start: Feb 2024Est. completion: May 202746 patients
N/ARecruiting
NCT06173687CochlearThe impedance measurement task using the Mobile Research App

Multi-center Study to Examine Changes to the Environment Surrounding the Electrodes in the Cochlea and to Capture the Most Challenging Listening Environments Experienced by Persons With a Cochlear Implant

Start: Jan 2024Est. completion: Oct 202451 patients
N/ACompleted

A Study Evaluating the Application of Hearing Aid Technologies to Signal Processing for Adult Cochlear Implant Recipients

Start: Sep 2023Est. completion: Jun 2026150 patients
N/AActive Not Recruiting

Individually-guided Hearing Aid Fitting

Start: Sep 2023Est. completion: Nov 202442 patients
N/ACompleted
NCT06638840OticonPediatric Performance and Satisfaction of Oticon Medical Ponto on Softband.

Pediatric Performance and Satisfaction of Oticon Medical Ponto on Softband.

Start: Jul 2023Est. completion: Oct 202464 patients
N/ACompleted
NCT05859568Advanced BionicsPinna-located Microphone

Baseline Performance and Fitting Parameters for Sonova Products

Start: Apr 2023Est. completion: Apr 202820 patients
N/AEnrolling By Invitation
NCT05709223CochlearCategorical loudness scaling based fitting using the Nexus Research System.

Comparing the Performance of a Categorical Loudness Scaling Based Fitting With a Behavioural Fitting in Adults With a Nucleus Cochlear Implant 3 Months Post-activation

Start: Mar 2023Est. completion: Feb 202517 patients
N/ACompleted

Assessing Speech Perception and Amplification Benefit During Infancy

Start: Mar 2023Est. completion: May 202536 patients
N/ACompleted

Telemonitoring in Cochlear Implant Patient Care

Start: Dec 2022Est. completion: Jun 202578 patients
N/ARecruiting
NCT05350046PhilipsEar-worn prototype devices

Development of Physical Activity Features for Ear-worn Devices

Start: Jul 2022Est. completion: Apr 202330 patients
N/ACompleted
NCT05176561Human BioSciencesAuditory-Cognitive Training

Auditory-Cognitive Training to Optimize Outcomes for Older CI Users

Start: May 2022Est. completion: Apr 202730 patients
N/AEnrolling By Invitation
NCT05356221OticonPonto Sound processor

Cross-sectional Evaluation of the Subjective Performance and Satisfaction With Ponto Sound Processors

Start: Apr 2022Est. completion: Sep 2024170 patients
N/ACompleted
NCT05274165Relief TherapeuticsLyric Hearing Aid- Experimental Design

Evaluation of New Fitting Characteristics for Extended Wear Hearing Aid Technology

Start: Mar 2022Est. completion: Sep 202225 patients
N/ACompleted

Investigation of an Updated Bone-anchored Sound Processor

Start: Sep 2021Est. completion: Dec 202115 patients
N/ACompleted
NCT04322747Gateway BiotechnologyDistortion product otoacoustic emissions

Hearing Changes After Surgery

Start: Sep 2021Est. completion: Feb 20220
N/AWithdrawn

Evaluation of Remote Fitting in Adult and Pediatric Users of the HiResolution Bionic Ear System

Start: Aug 2021Est. completion: May 202219 patients
N/ACompleted

Internet Auditory Rehabilitation: Follow-up to Adult Hearing Screening

Start: Aug 2021Est. completion: Dec 202331 patients
N/ACompleted
NCT04754477CochlearActive Osseointegrated Steady-State Implant System

Long Term Clinical Investigation to Evaluate Clinical Performance, Safety and Patient Reported Outcomes of an Active Osseointegrated Steady-State Implant System

Start: May 2021Est. completion: Mar 202220 patients
N/ACompleted
NCT04231396Oregon TherapeuticsAudiobooks for hearing loss App

Audiobooks for Hearing Loss App as Auditory Training

Start: Feb 2021Est. completion: Sep 202127 patients
N/ACompleted
NCT04310202OticonAbbreviated Profile of Hearing Aid Benefit

Multi-Centre Study on the Performance of the Ponto BHX Implant System (in Adult Patients)

Start: Jan 2021Est. completion: Dec 202350 patients
N/ACompleted
NCT05270876CochlearCochlear Implant and sound processor device fitting paradigm or diagnostic/measurement technique

Innovations in Clinical Care of CE Approved Nucleus Cochlear Implant Recipients

Start: Oct 2020Est. completion: Mar 202320 patients
N/ACompleted
NCT04559282CochlearNew Sound Processor

Home Test of New Sound Processor

Start: Sep 2020Est. completion: Nov 202016 patients
N/ACompleted
NCT04279236OticonAbbreviated Profile Hearing Aid Benefit

Multi-Center Study on Performance of the Ponto Implant System Using Minimally Invasive Ponto Surgery (in Adult Patients)

Start: Jun 2020Est. completion: Dec 202464 patients
N/ACompleted

Sound Processing Innovations in Adult and Paediatric Cochlear Implant Recipients.

Start: Jan 2020Est. completion: Mar 20238 patients
N/ACompleted
NCT04237207Advanced BionicsNaída Cochlear Implant Q90 sound processor

Clinical Evaluation of a Cochlear Implant Sound Processor

Start: Dec 2019Est. completion: Oct 202022 patients
N/ACompleted
NCT04041700CochlearOsia 2 system

Clinical Performance, Safety and Patient Reported Outcomes of an Active Osseointegrated Steady-State Implant System

Start: Aug 2019Est. completion: Sep 202029 patients
N/ACompleted
NCT05058066CochlearBaha® flange fixture

10-year Follow-up of a Wide Diameter Bone Anchored Hearing Implant

Start: Jun 2019Est. completion: Sep 202051 patients
N/ACompleted
NCT03662256Sound PharmaceuticalsCurrent Primary Care Referral Process

Reducing Childhood Hearing Loss in Rural Alaska Through a Preschool Screening and Referral Process Using Mobile Health and Telemedicine

Start: Sep 2018Est. completion: Feb 2020155 patients
N/ACompleted
NCT03279367Physical SciencesObjective speech response detection

Optimisation of Hearing Aid Fitting

Start: Dec 2017Est. completion: Sep 201820 patients
N/ACompleted
NCT03072862CochlearCommercial Nucleus Cochlear Implant Systems

Evaluation of the Benefits for Overall Health Following Cochlear Implant Treatment in the Elderly Population

Start: Nov 2017Est. completion: Mar 2022100 patients
N/ACompleted
NCT03410017CochlearFunctional Listening Index

FLI Normative Study

Start: Nov 2017Est. completion: Dec 2018536 patients
N/ACompleted

Phase Legend

PreclinicalLab & animal studies
Phase 1Safety & dosing
Phase 2Efficacy testing
Phase 3Large-scale trials
On MarketApproved & available

Key Insights

8 actively recruiting trials targeting 3,575 patients
19 companies competing in this space

The information on this page is for informational purposes only and should not be used as a substitute for professional medical advice. Drug information is sourced from FDA, DailyMed, and other government databases. Adverse event data from FAERS does not establish causation. Always consult a healthcare professional for medical decisions.