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Healthy Adult Subjects

21
Pipeline Programs
15
Companies
32
Clinical Trials
1 recruiting
0
Approved Products

Pipeline by Development Stage

Preclinical
Phase 1
Phase 1/2
Phase 2
Phase 2/3
Phase 3
On Market
0
21
0
0
0
0
0
Early DiscoveryClinical DevelopmentMarket

Drug Modality Breakdown

Small Molecule
1100%
+ 30 programs with unclassified modality

Competitive Landscape

15 companies ranked by most advanced pipeline stage

Ono Pharmaceutical
Ono PharmaceuticalJapan - Osaka
9 programs
9
ONO-2952Phase 11 trial
ONO-2952Phase 11 trial
ONO-4053Phase 11 trial
ONO-4053Phase 11 trial
ONO-6950Phase 11 trial
+4 more programs
Active Trials
NCT01613703Completed16
NCT01364441Completed48
NCT01537172Completed80Est. Aug 2012
+6 more trials
Biocorp
BiocorpFrance - Issoire
2 programs
2
FG-4592Phase 11 trial
RoxadustatPhase 1Small Molecule1 trial
Active Trials
NCT01376063Completed20Est. Jun 2010
NCT03960489Completed24Est. Oct 2019
Yunovia
YunoviaKorea - Hwaseong
2 programs
2
ID110521156Phase 1
ID110521156Phase 1
Ildong Pharmaceutical
2 programs
2
ID110521156Phase 11 trial
ID110521156Phase 11 trial
Active Trials
NCT06063291Completed36Est. Jul 2024
NCT06635226Recruiting36Est. Jun 2025
Prevail Therapeutics
2 programs
2
PegilodecakinPhase 11 trial
PegilodecakinPhase 11 trial
Active Trials
NCT03267732Completed24Est. Oct 2017
NCT03381547Completed12Est. Feb 2018
Kashiv BioSciences
Kashiv BioSciencesNJ - Piscataway
1 program
1
ADL-018 AutoinjectorPhase 11 trial
Active Trials
NCT06929052Completed150Est. Aug 2025
Alvotech
AlvotechLUXEMBOURG, Luxembourg
1 program
1
AVT05Phase 11 trial
Active Trials
NCT05632211Completed336Est. Oct 2023
Microbiotix
MicrobiotixMA - Worcester
1 program
1
MBX-400Phase 11 trial
Active Trials
NCT01433835Completed48Est. Sep 2012
Bausch Health
Bausch HealthQUEBEC, Quebec, Canada
1 program
1
methylnaltrexonePhase 11 trial
Active Trials
NCT01366378Completed18Est. Feb 2007
Connect Biopharma
Connect BiopharmaSAN DIEGO, CA
3 programs
CBP-174PHASE_11 trial
CBP-307PHASE_11 trial
Test drugPHASE_11 trial
Active Trials
NCT04811469Completed74Est. May 2022
NCT05040113Completed6Est. Oct 2021
NCT05917782Completed324Est. Oct 2023
Biogen
BiogenCAMBRIDGE, MA
2 programs
BIIB118PHASE_11 trial
OmaveloxolonePHASE_15 trials
Active Trials
NCT02691702Completed97Est. Jan 2017
NCT07019064Completed52Est. Aug 2025
NCT06054893Active Not Recruiting33Est. Nov 2030
+3 more trials
Fulcrum Therapeutics
2 programs
FTX-6058/placebo oral capsulePHASE_11 trial
Losmapimod 15 mg oral tabletPHASE_11 trial
Active Trials
NCT04586985Completed109Est. Nov 2022
NCT05002231Completed18Est. Oct 2021
Thea Pharma
Thea PharmaMA - Waltham
1 program
T2309N/A1 trial
Active Trials
NCT04596605CompletedEst. Mar 2021
IQVIA
IQVIADURHAM, NC
1 program
AVT05PHASE_1
Eli Lilly and Company
Eli Lilly and CompanyINDIANAPOLIS, IN
1 program
PegilodecakinPHASE_1

Trial Timeline

Clinical trial activity over time

2021
2022
2023
2024
2025
2026
2027
2028
2029
2030
BiogenOmaveloxolone
Kashiv BioSciencesADL-018 Autoinjector
Ildong PharmaceuticalID110521156
BiogenOmaveloxolone
Ildong PharmaceuticalID110521156
Connect BiopharmaTest drug
BiogenOmaveloxolone
BiogenOmaveloxolone
AlvotechAVT05
Connect BiopharmaCBP-307
Fulcrum TherapeuticsLosmapimod 15 mg oral tablet
Connect BiopharmaCBP-174
Fulcrum TherapeuticsFTX-6058/placebo oral capsule
BiocorpRoxadustat
BiogenOmaveloxolone

Showing 15 of 32 trials with date data

Clinical Trials (32)

Total enrollment: 1,967 patients across 32 trials

NCT07019064BiogenOmaveloxolone

A Study to Learn How BIIB141 (Omaveloxolone) is Processed in the Body When Taken as Capsules Compared to Sprinkled on Yogurt in Healthy Adults Aged 18 to 55

Start: Jun 2025Est. completion: Aug 202552 patients
Phase 1Completed
NCT06929052Kashiv BioSciencesADL-018 Autoinjector

A Comparative Pharmacokinetic Study of ADL-018 Autoinjector Compared to A Pre-filled Syringe in Healthy Subjects.

Start: Jan 2025Est. completion: Aug 2025150 patients
Phase 1Completed

Safety, Tolerability, Pharmacokinetics and Pharmacodynamics of ID110521156 in Healthy Adult Subjects

Start: Nov 2024Est. completion: Jun 202536 patients
Phase 1Recruiting
NCT06054893BiogenOmaveloxolone

A Study to Find Out How BIIB141 (Omaveloxolone) is Processed in the Body and to Learn More About Its Safety in Participants With Friedreich's Ataxia Aged 2 to 15 Years Old

Start: Jul 2024Est. completion: Nov 203033 patients
Phase 1Active Not Recruiting

Single Ascending Oral Dose Phase 1 Study of ID110521156 in Healthy Adult Subjects

Start: Nov 2023Est. completion: Jul 202436 patients
Phase 1Completed

A Study to Evaluate the Pharmacokinetics Similarity of CBP-201 in Healthy Adult Chinese Subjects

Start: Jul 2023Est. completion: Oct 2023324 patients
Phase 1Completed
NCT05927649BiogenOmaveloxolone

A TQTc Study for Omaveloxolone

Start: Jul 2023Est. completion: Sep 202330 patients
Phase 1Completed
NCT05909644BiogenOmaveloxolone

An Open-label DDI Study of Omaveloxolone in Healthy Subjects

Start: Jul 2023Est. completion: Aug 202320 patients
Phase 1Completed

A Study to Investigate the PK, Safety, and Tolerability Between AVT05, US and EU Simponi® in Healthy Adult Participants

Start: Dec 2022Est. completion: Oct 2023336 patients
Phase 1Completed

A Study On Human Mass Balance And Biotransformation

Start: Sep 2021Est. completion: Oct 20216 patients
Phase 1Completed
NCT05002231Fulcrum TherapeuticsLosmapimod 15 mg oral tablet

Relative Bioavailability and Food Effect Study of Losmapimod 15 mg Tablets

Start: Aug 2021Est. completion: Oct 202118 patients
Phase 1Completed

Safety, Tolerability and Pharmacokinetics of CBP-174 in Healthy Adults

Start: May 2021Est. completion: May 202274 patients
Phase 1Completed
NCT04586985Fulcrum TherapeuticsFTX-6058/placebo oral capsule

Safety, Tolerability and Pharmacokinetics of FTX-6058

Start: Oct 2020Est. completion: Nov 2022109 patients
Phase 1Completed

A Study to Assess the Relative Bioavailability of Roxadustat Following a Single Dose of Pediatric Azo Dye-free Tablet Formulation and Pediatric Azo Dye-free Mini-tablet Formulation Compared to a Single Dose of Azo Dye-containing Tablet Formulation in Healthy Adult Subjects

Start: Jul 2019Est. completion: Oct 201924 patients
Phase 1Completed
NCT04008186BiogenOmaveloxolone

A Clinical Drug-Drug Interaction (DDI) Study With Omaveloxolone

Start: Jun 2019Est. completion: Aug 201961 patients
Phase 1Completed
NCT03664453BiogenOmaveloxolone

A Pharmacokinetic Study of Omaveloxolone in Healthy Volunteers

Start: Oct 2018Est. completion: Nov 201832 patients
Phase 1Completed

A 3-Way Crossover Study to Evaluate the Pharmacokinetics in Participants After Dosing With Pegilodecakin (LY3500518)

Start: Dec 2017Est. completion: Feb 201812 patients
Phase 1Completed

A Study to Evaluate the Pharmacokinetics in Participants After Dosing With Pegilodecakin (LY3500518)

Start: Sep 2017Est. completion: Oct 201724 patients
Phase 1Completed

Multiple Dose Study Of BIIB118 (PF-05251749) In Healthy Volunteers

Start: Mar 2016Est. completion: Jan 201797 patients
Phase 1Completed

ONO-2952 Single-dose PET Study in Healthy Adult Subjects

Start: Aug 201216 patients
Phase 1Completed

A Phase I Study to Evaluate Safety, Tolerability and Pharmacokinetics of ONO-4053 in Healthy Volunteers

Start: Jan 2012Est. completion: Aug 201280 patients
Phase 1Completed

Single Dose Escalation Study of ONO-9054 in Healthy Volunteers

Start: Jan 201248 patients
Phase 1Completed

Safety and Pharmacokinetics of Single Oral Doses of MBX-400 in Healthy Volunteers

Start: Sep 2011Est. completion: Sep 201248 patients
Phase 1Completed

Safety, Tolerability, Pharmacokinetics and Pharmacodynamics of ONO-6950 in Healthy Adult Subjects

Start: Jul 201124 patients
Phase 1Completed

A Phase I Study to Evaluate Safety, Tolerability and Pharmacokinetics of ONO-4053 in Healthy Volunteers

Start: Jun 201115 patients
Phase 1Terminated

Single-Dose Study to Evaluate the Safety, Tolerability, and Pharmacokinetics of ONO-2952 in Healthy Adult Subjects

Start: May 201148 patients
Phase 1Completed

Study to Evaluate the Safety, Tolerability, Pharmacokinetics and Pharmacodynamics of ONO-6950 in Healthy Adult Subjects

Start: Jan 201156 patients
Phase 1Completed

ONO-7746 Study in Healthy Adult Subject

Start: Apr 201072 patients
Phase 1Completed

Study to Investigate the Interaction Between FG-4592 and Rosiglitazone in Healthy Adult Subjects

Start: Mar 2010Est. completion: Jun 201020 patients
Phase 1Completed

ONO-7746 Study in Healthy Adult Subjects

Start: Aug 200948 patients
Phase 1Completed
NCT01366378Bausch Healthmethylnaltrexone

Effect of Cimetidine on the Single-Dose PK of IV- Administered MNTX

Start: Jan 2007Est. completion: Feb 200718 patients
Phase 1Completed

Gastrointestinal Tolerance Assessment of T2309

Start: Jul 2020Est. completion: Mar 2021
N/ACompleted

Phase Legend

PreclinicalLab & animal studies
Phase 1Safety & dosing
Phase 2Efficacy testing
Phase 3Large-scale trials
On MarketApproved & available

Key Insights

1 actively recruiting trials targeting 1,967 patients
15 companies competing in this space

The information on this page is for informational purposes only and should not be used as a substitute for professional medical advice. Drug information is sourced from FDA, DailyMed, and other government databases. Adverse event data from FAERS does not establish causation. Always consult a healthcare professional for medical decisions.