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Guillain-Barré Syndrome

4
Pipeline Programs
5
Companies
10
Clinical Trials
1 recruiting
0
Approved Products

Pipeline by Development Stage

Preclinical
Phase 1
Phase 1/2
Phase 2
Phase 2/3
Phase 3
On Market
0
1
0
0
0
3
0
Early DiscoveryClinical DevelopmentMarket

Drug Modality Breakdown

Monoclonal Antibody
1100%
+ 4 programs with unclassified modality

Competitive Landscape

5 companies ranked by most advanced pipeline stage

Annexon Biosciences
Annexon BiosciencesCA - Brisbane
1 program
1
ANX005Phase 35 trials
Active Trials
NCT07020819Recruiting30Est. Jun 2028
NCT04691570Completed6Est. Jan 2023
NCT04569435Completed17Est. Apr 2024
+2 more trials
Japan Blood Products Organization
1 program
1
GB-0998Phase 31 trial
Active Trials
NCT02342184Completed21Est. Sep 2015
Nihon Pharmaceutical
1 program
1
NPB-01Phase 31 trial
Active Trials
NCT02221271Completed22Est. Aug 2015
Cellenkos
CellenkosTX - Houston
1 program
1
CK0801Phase 11 trial
Active Trials
NCT03773328Withdrawn0Est. Feb 2027
Chugai Pharma
Chugai PharmaJapan - Tokyo
1 program
CrovalimabPHASE_3Monoclonal Antibody

Trial Timeline

Clinical trial activity over time

2021
2022
2023
2024
2025
2026
2027
2028
Annexon BiosciencesANX005
Annexon BiosciencesANX005
Nihon PharmaceuticalNPB-01
Japan Blood Products OrganizationGB-0998
Annexon BiosciencesANX005
Annexon BiosciencesANX005
Annexon BiosciencesANX005
CellenkosCK0801
Annexon BiosciencesANX005
Annexon BiosciencesANX005

Clinical Trials (10)

Total enrollment: 407 patients across 10 trials

An Open Label Clinical Study to Evaluate Tanruprubart (Also Commonly Known as ANX005) in Participants With Guillain-Barré Syndrome (FORWARD Study)

Start: Sep 2025Est. completion: Jun 202830 patients
Phase 3Recruiting

Efficacy and Safety of ANX005 in Subjects With Guillain-Barré Syndrome

Start: Dec 2020Est. completion: Apr 2024242 patients
Phase 3Completed

Phase III Clinical Trial of NPB-01 in Patients With Guillain-Barré Syndrome

Start: Oct 2014Est. completion: Aug 201522 patients
Phase 3Completed

Efficacy and Safety Study of GB-0998 for Guillain-Barré Syndrome

Start: Aug 2014Est. completion: Sep 201521 patients
Phase 3Completed

Safety, Tolerability, Pharmacokinetics and Pharmacodynamics of ANX005 in Participants With Warm Autoimmune Hemolytic Anemia (wAIHA)

Start: Nov 2021Est. completion: Jan 20236 patients
Phase 2Completed

Study of ANX005 in Adults With Amyotrophic Lateral Sclerosis (ALS)

Start: Jan 2021Est. completion: Apr 202417 patients
Phase 2Completed

An Open Label Study of ANX005 in Subjects With, or at Risk for, Manifest Huntington's Disease

Start: Aug 2020Est. completion: Jan 202228 patients
Phase 2Completed

A Clinical Trial of CK0801 (a New Drug) In Patients With Treatment-Resistant Guillain-Barré Syndrome (GBS)

Start: Nov 2022Est. completion: Feb 20270
Phase 1Withdrawn

A Clinical Study of ANX005 and IVIG in Subjects With Guillain Barré Syndrome (GBS)

Start: Jan 2020Est. completion: May 202114 patients
Phase 1Completed

Single Dose Study of ANX005 in Healthy Volunteers

Start: Dec 2016Est. completion: Jun 201827 patients
Phase 1Terminated

Related Jobs

Phase Legend

PreclinicalLab & animal studies
Phase 1Safety & dosing
Phase 2Efficacy testing
Phase 3Large-scale trials
On MarketApproved & available

Key Insights

3 late-stage (Phase 3) programs, potential near-term approvals
1 actively recruiting trials targeting 407 patients
5 companies competing in this space

The information on this page is for informational purposes only and should not be used as a substitute for professional medical advice. Drug information is sourced from FDA, DailyMed, and other government databases. Adverse event data from FAERS does not establish causation. Always consult a healthcare professional for medical decisions.