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Glioblastom WHO Grade 4

2
Pipeline Programs
2
Companies
4
Clinical Trials
2 recruiting
0
Approved Products

Pipeline by Development Stage

Preclinical
Phase 1
Phase 1/2
Phase 2
Phase 2/3
Phase 3
On Market
0
2
0
0
0
0
0
Early DiscoveryClinical DevelopmentMarket

Competitive Landscape

2 companies ranked by most advanced pipeline stage

Alpheus Medical
Alpheus MedicalMN - Chanhassen
1 program
1
5-ALAPhase 13 trials
Active Trials
NCT07862647Recruiting30Est. Mar 2028
NCT07225621Recruiting103Est. Dec 2028
NCT06665724Completed16Est. Feb 2026
Biocorp
BiocorpFrance - Issoire
1 program
1
Lu-177 labeled 6A10-Fab-fragmentsPhase 11 trial
Active Trials
NCT05533242Terminated10Est. Sep 2026

Trial Timeline

Clinical trial activity over time

2024
2025
2026
2027
2028
Alpheus Medical5-ALA
Alpheus Medical5-ALA
Alpheus Medical5-ALA
BiocorpLu-177 labeled 6A10-Fab-fragments

Clinical Trials (4)

Total enrollment: 159 patients across 4 trials

Adjuvant Temozolomide ± 5-Aminolevulinic Acid + Low Intensity Diffuse Ultrasound Sonodynamic Therapy System for Newly Diagnosed Glioblastoma

Start: Jan 2026Est. completion: Dec 2028103 patients
Phase 2Recruiting

TMZ + RT + 5-ALA + LIDU SDT System for Newly Diagnosed Butterfly Glioma

Start: Oct 2026Est. completion: Mar 202830 patients
Phase 1Recruiting

Clinical Trial Evaluating Safety of 5-Aminolevulinic Acid (5-ALA) Combined With CV01 Delivery of Ultrasound for Sonodynamic Therapy (SDT) in Patients With Newly Diagnosed High-Grade Glioma (HGG) Prior to Resection and Standard Adjuvant Therapy (ALA SDT GLIOMA 401)

Start: Jan 2025Est. completion: Feb 202616 patients
Phase 1Completed
NCT05533242BiocorpLu-177 labeled 6A10-Fab-fragments

Radioimmunotherapy With Lu-177 Labeled 6A10 Fab-fragments in Patients With Glioblastoma After Standard Treatment

Start: Jan 2024Est. completion: Sep 202610 patients
Phase 1Terminated

Phase Legend

Preclinical— Lab & animal studies
Phase 1— Safety & dosing
Phase 2— Efficacy testing
Phase 3— Large-scale trials
On Market— Approved & available

Key Insights

2 actively recruiting trials targeting 159 patients
2 companies competing in this space

The information on this page is for informational purposes only and should not be used as a substitute for professional medical advice. Drug information is sourced from FDA, DailyMed, and other government databases. Adverse event data from FAERS does not establish causation. Always consult a healthcare professional for medical decisions.